Clinical risk factors for the generation of life events in major depression.

This study examines the relationship of anxiety disorder and dysthymia comorbidity to the generation of life events prior to major depression episode onset in a cross-sectional community sample of 76 women. Those with comorbid anxiety and dysthymia experienced higher rates of events that were at least partly dependent on their own behavior but did not differ from those without these clinical risk factors on independent life events outside of their control. This relationship remained significant even after controlling for overall severity of depression and demographic covariates. The implications of these results for understanding the increased rates of major depression onset and recurrence among those with comorbid anxiety and dysthymia are discussed as avenues of future research.     

Attributions for negative life events and depression: the role of perceived control

Although perceptions of control occupied a central role in the development of learned helplessness theory, recent helplessness research has not considered controllability judgments when relating attributions to depression. Supporting the importance of this construct, the research discussed in this article found evidence that judgments of control interact with other attributions in predicting depression. Specifically, in a prospective study of stress and well-being in adolescence, internal, stable, and global attributions for negative events attributed to uncontrollable causes were found to be positively related to increases in depression (as predicted by the reformulated helplessness theory), but internal and global attributions for negative events attributed to controllable causes were found to be inversely related to increases in depression. The discussion considers the implications of the findings for understanding the nature of the relation between attributions for naturally occurring life events and depression.     

Inventorying stressful life events as risk factors for psychopathology: Toward resolution of the problem of intracategory variability

An explosion of research on life events has occurred since the publication of the Holmes and Rahe checklist in 1967. Despite criticism, especially of their use in research on psychopathology, such economical inventories have remained dominant. Most of the problems of reliability and validity with traditional inventories can be traced to the intracategory variability of actual events reported in their broad checklist categories. The purposes of this review are, first, to examine how this problem has been addressed within the tradition of economical checklist approaches; second, to determine how it has been dealt with by far less widely used and far less economical labor-intensive interview and narrative-rating approaches; and, third, to assess the prospects for relatively economical, as well as reliable and valid, solutions.     

Life events and depression in adolescence: relationship loss as a prospective risk factor for first onset of major depressive disorder

Although stressful life events have consistently been linked to the onset of major depressive disorder (MDD), most research has not distinguished 1st episodes from recurrences. In a large epidemiologic sample of older adolescents (N = 1,470) assessed at 2 time points, the risk conferred by a recent romantic break-up was examined as a predictor of 1st onset versus recurrence of MDD. Results indicated a heightened likelihood of 1st onset of MDD during adolescence if a recent break-up had been reported; in contrast, a recent break-up did not predict recurrence of depression. These results held for both genders and remained significant after controlling for gender. Additional analyses to determine the discriminant validity and specificity of these findings strongly supported the recent break-up as a significant risk factor for a 1st episode of MDD during adolescence. Implications of these findings and subsequent research directions are discussed.     

Event-specific attributions and daily life events as predictors of depression symptom change

A prospective study was conducted to investigate whether event-specific attributions, either alone or in interaction with daily life events predict depression symptom change, and whether this is affected by systematic variation in intertest intervals. Baseline measures of attributional style, event-specific attributions, life events, and depression were administered to 96 adults enrolled in a cigarette-smoking cessation program who were readministered the event-specific attributions, life events, and depression measures 2, 4, 6, and 8 weeks later. Results indicated that (a) the interaction between event-specific attributions and life events was a better predictor of depression symptom change than were event-specific attributions alone; (b) event-specific attributions and life events demonstrated a tendency to predict depression symptom change over 2 and 4 weeks but not over 6 and 8 weeks; (c) the stability and globality of event-specific attributions was associated with the number of reported life events; and (d) baseline attributional style predicted event-specific attributions 2, 4, 6, and 8 weeks later.     

Suicide, schizophrenia, and schizoid-type psychosis: role of life events and childhood factors

The first objective was to identify the provoking events of suicide in patients with schizophrenia or schizoid-type disorder, and to assess the humiliation component of these events. The second objective was to verify if quality of care during childhood is a vulnerability factor for suicide in patients with schizophrenia or schizoid-type psychosis. Thirty-three cases of suicide with a diagnosis of schizophrenia or schizoid-type psychosis were compared with 34 living patients with a similar diagnosis. The psychological autopsy method was used. The assessments were made with the Structured Clinical Interview for the Diagnostic and Statistical Manual for Axis I mental disorders, the Life Events and Difficulties Schedule, and the Child Experiences and Child Abuse Interview. The suicide group (SG) experienced more often a recent severe event, usually of a humiliation nature, than the control group (CG). It also experienced more severe events associated with aggressive behavior or with psychiatric impairment. Contrary to expectations, the CG had worse scores than the SG for quality of care during childhood. In conclusion, suicide in schizophrenia is related both to environmental stress and to psychiatric impairment.     

Congruence of personality and life events in depression

Consistent with the personality-event congruence hypothesis, highly sociotropic depressed patients (n = 19) reported more recent negative interpersonal events than negative autonomy events and more negative interpersonal events than did highly autonomous depressed patients (n = 22), for whom the hypothesis was not supported. There was no evidence of such congruence among nondepressed schizophrenic patients (n = 44). In a second study, there was significant personality-event congruence in dysphoric students (n = 26) but not in nondysphoric students (n = 56). Both the high-sociotropy and high-autonomy dysphoric groups separately yielded nonsignificant trends consistent with congruence. These findings add to the growing support for the importance of the sociotropy construct in depression and weaker support for the autonomy construct or its measurement, and they suggest that the congruence effect does not generalize to all psychopathologies.     

The role of childhood abuse and neglect in the sensitization to stressful life events in adolescent depression

This study examined the role of childhood abuse and neglect in sensitizing adolescents to the effects of proximal stressful life events in a cross-sectional sample of 103 depressed and nondepressed adolescents. Consistent with hypotheses, adolescents with a history of childhood abuse and/or neglect reported a lower level of threat of stressful life events prior to episode onset than that reported by those without. This effect was specific to those on their 1st episode of depression and was specific to independent events (i.e., stressors outside of adolescents' control). Further, this effect was robust when controlling for level of chronic difficulties, which was higher in those with childhood abuse and/or neglect. The authors suggest that childhood abuse and/or neglect may be an important risk factor that sensitizes individuals to the effects of acute independent life events.     

Rumination as a common mechanism relating depressive risk factors to depression

Rumination was examined as a potential common mechanism linking risk factors with depression. Initially nondepressed individuals (N = 137) were assessed for presence of a ruminative response style and 4 other hypothesized risk factors for depression. They were followed for 2.5 years. Negative cognitive styles, self-criticism, dependency, neediness, and history of past depression were all significantly associated with rumination. Rumination mediated the predictive relationships of all risk factors except dependency with the number of prospective Diagnostic and Statistical Manual of Mental Disorders (3rd ed., rev.; American Psychiatric Association, 1987) major depressive episodes (MDEs; definite and subthreshold) during the follow-up period. In contrast, private self-consciousness did not mediate any relationships between risk factors and subsequent MDEs. Thus, rumination, as a special kind of self-focus, may act as a general proximal mechanism through which other vulnerability factors affect depression.     

Religiousness and depression: evidence for a main effect and the moderating influence of stressful life events

The association between religiousness and depressive symptoms was examined with meta-analytic methods across 147 independent investigations (N = 98,975). Across all studies, the correlation between religiousness and depressive symptoms was -.096, indicating that greater religiousness is mildly associated with fewer symptoms. The results were not moderated by gender, age, or ethnicity, but the religiousness-depression association was stronger in studies involving people who were undergoing stress due to recent life events. The results were also moderated by the type of measure of religiousness used in the study, with extrinsic religious orientation and negative religious coping (e.g., avoiding difficulties through religious activities, blaming God for difficulties) associated with higher levels of depressive symptoms, the opposite direction of the overall findings.     

Characterizing the role of strategic disposition and orientation to risk in wayfinding

Although digital navigation systems are becoming ubiquitous, they generally only select routes based on relatively simple criteria (length and time) and fail to adequately consider the preferred strategy of the user. In order to account for these strategies, care must be taken to solicit not only simple preferences, but also deeper issues such as overall strategic disposition and attitudes toward risk. Hallmarks of true strategy include schematic, general, conditional and conscious consideration of the impact of important variables on the achievement of one’s goals. Factor analysis of a 40-item questionnaire isolated five questions that well-account for the strategic disposition of individuals. Additionally, attitudes about risk were explored in pedestrian and driving contexts. This analysis suggests that within the individual, attitudes about risk are relatively fixed, yet the manifestation of risk-seeking behavior is dependent on the mode of travel.     

Anger, anxiety, and depression as risk factors for cardiovascular disease: the problems and implications of overlapping affective dispositions

Several recent reviews have identified 3 affective dispositions--depression, anxiety, and anger-hostility--as putative risk factors for coronary heart disease. There are, however, mixed and negative results. Following a critical summary of epidemiological findings, the present article discusses the construct and measurement overlap among the 3 negative affects. Recognition of the overlap necessitates the development of more complex affect-disease models and has implications for the interpretation of prior studies, statistical analyses, prevention, and intervention in health psychology and behavioral medicine. The overlap among the 3 negative dispositions also leaves open the possibility that a general disposition toward negative affectivity may be more important for disease risk than any specific negative affect.     

The role of life events in the onset of panic disorder

Twenty-five panic disorder patients and fifteen obsessive-compulsive patients are compared with regard to a number of Life Events over the last 12 months prior to onset of the disorder and additionally over the total life course up until onset of the disorder. Panic Disorder patients do not differ from obsessive-compulsive disorder patients in terms of the number of life events, they experience during the last year prior to onset of their disorder. However, over the total life course, Panic Disorder patients do seem to be exposed to more Life Events than obsessive-compulsive disorder patients. The findings are discussed in light of the existing literature.     

Neighborhood context, personality, and stressful life events as predictors of depression among African American women

The authors tested neighborhood context, negative life events, and negative affectivity as predictors of the onset of major depression among 720 African American women. Neighborhood-level economic disadvantage (e.g., percentage of residents below the poverty line) and social disorder (e.g., delinquency, drug use) predicted the onset of major depression when controlling for individual-level demographic characteristics. Neighborhood-level disadvantage/disorder interacted with negative life events, such that women who experienced recent negative life events and lived in high disadvantage/disorder neighborhoods were more likely to become depressed than were those who lived in more benign settings, both concurrently and over a 2-year period. Neighborhood disadvantage/disorder can be viewed as a vulnerability factor that increases susceptibility to depression following the experience of negative life events.     

The mediation component of the hopelessness depression in relation to negative life events

A necessary test of the mediational processes component of the hopelessness theory of depression is to test whether the individuals who have negative attributional style and experience negative life events are likely to make negative attributions for the negative events they confront. The present study, using undergraduate students, find that the negative attributional style do not predict negative attributions subjects made for the negative life events they experience within a period of 3 months. However, subjects' negative attributions for the negative life events coupled with the experience of a high number of negative life events predicted their depressive symptomatology. The depressive symptomatology is found not to be mediated through hopelessness. The findings are discussed in relation to the hopelessness theory of depression.     

Moods and Memories: Elation, depression, and the remembering of the events of one's life

Three experiments investigated the influence of current mood states on the remembering of past events of one's own life. In the first and the second experiment, participants were induced to experience either the mood state of elation or the mood state of depression. They then reported events and experiences that had occurred during the previous week. In the first and the second experiments, using converging methods for assessing memory for past events, participants differentially reported past events and experiences whose affective quality was congruent with their current mood states: participants in elated mood states preferentially reported pleasant events and happy experiences, and participants in depressed mood states preferentially reported unpleasant events and unhappy experiences. Additional evidence from the second experiment suggests that the differential remembering of affectively positive or affectively negative events requires that, at the time of the remembering of these events, participants actually experience the mood states of elation or depression and not simply attempt to remember past events that could account for elation or depression. In the third experiment, designed to assess the plausibility of “experimental demand” interpretations of these findings, participants who experienced ostensibly effective mood inductions that were actually ineffective failed to manifest differential remembering of affectively positive and affectively negative events. Implications of this series of experiments for understanding the mechanisms that may link moods and memories, as well as the intrapersonal and the interpersonal consequences of mood states, are discussed.     

The enduring impact of borderline personality pathology: risk for threatening life events in later middle-age

Both neuroticism and borderline personality disorder (BPD) are associated with increased frequency of stressful life events in young adults. It is not clear, however, whether this effect extends to later life because BPD is apparently diminished in frequency and severity when people reach middle adulthood. This issue was examined in a representative, community sample of men and women between the ages of 55 and 64 (N = 1,234). Ten DSM-IV PDs and neuroticism were assessed at baseline using a semistructured interview (SIDP-IV) and questionnaire (NEO-PI-R). Life events were measured 6 months later with a self-report questionnaire (LTE-Q) followed by a telephone interview. BPD features and neuroticism predicted increased frequency of life events, based on both self and interviewer-adjusted reports of negative life events. Avoidant and paranoid PD features predicted decreased frequency of negative life events. Approximately 42% of events reported on the LTE-Q were discounted following the telephone interview; higher scores on BPD symptoms were associated with more adjustments to self-report of threatening experiences. These findings indicate that symptoms of BPD and neuroticism continue to have a harmful impact on the lives of older adults.     

The role of recent life events in the onset of obsessive-compulsive disorder

Although many investigations into the onset of obsessive-compulsive disorder (OCD) suggest the occurrence of potential life events as triggering factors, such an association has not been well studied to date. The purpose of the present paper is to review the literature on OCD onset in order to determine whether OCD is triggered by recent life events, what specific events may serve as triggers, and the clinical and research implications of these factors. Overall, the available studies do not consistently support the theory that OCD is triggered by specific antecedent life events. However, there is a body of evidence to support the theory that the specific life events of pregnancy and birth of a child can trigger OCD. This apparent association has led to the investigation of certain neurohormonal factors, including changes in estrogen or oxytocin levels, that may be of etiopathogenetic significance in OCD. Confirming such associations may allow clinicians to provide more targeted preventive and therapeutic interventions.