Differential diagnosis of endogenous psychoses in relation to a symptom catalog

The paper introduces a catalog of symptoms to promote in the field of endogenous psychoses differentiated diagnosis, at the same time constituting a prognosis. Symptoms should be more minutely differentiated than is customary in psychiatric questionnaires. Manic-depressive disorders and purely phasal psychoses are distinguished solely in the clinical evaluation. Thus benign cycloid psychoses can be distinguished from malignant unsystematic schizophrenia.     

Some suggestions on epileptic psychoses, their differential diagnosis and therapy

From a present point of view, some clinical suggestions are put forward concerning the symptomatology, differential diagnostics, and therapy of psychotic states in epileptic patients (twilight states, states of emotional deterioration and epileptic psychoses proper).     

Catamnestic surveys on somato-psychosocial development in childhood and adolescence of patients with unipolar depressive and bipolar manic-depressive psychoses

The somatic and psychosocial development of 80 subjects with manifest affective-phasic psychoses is studied retrospectively and compared with that of an identically sized control group consisting of neuropsychiatrically healthy subjects. Statistically significant differences were found particularly in the answers to questions dealing with social situation and social adaptability. Achievement at school and vocational qualifications were lower among the parents of the patients than among those of the healthy subjects. Characteristic features of the patients' childhood and adolescence were transient depression, often for no apparent cause, and maladaption, and vocational wishes were fulfilled less often than among the controls. The patients experienced greater difficulty in settling in to a new group due to their contact difficulties.     

Differential diagnosis of cluttering and stuttering in Bulgaria

Fifteen stutterers, primarily children, who visited the Medical Pedagogical Department at the University of Blagoevgrad were evaluated for a variety of criteria used in Bulgaria to differentiate cluttering, stuttering, and mixed cluttering and stuttering. The same battery of tests was administered to all subjects. Based on these criteria, five subjects were diagnosed as clutterers, six as stutterers, and four as mixed. Daly's (1992–1993) Checklist for Possible Cluttering, Experimental Edition was also utilized to classify the subjects. Differences between the differential diagnostic criteria used by Bulgarian logopedists and other authors are discussed.     

Determination of similarity and dissimilarity of endogenous psychoses in monozygotic twins based on a differential diagnosis

The frequently published opinion that endogenous psychoses in monozygotic twins often show a marked lack of similarity could not be confirmed by the results of studies performed by the author and his associates. In general, differenting diagnosis allows the particular syndrome, on which the establishment of the respective diagnosis is based, to be nearly always observed in either partner. On the other hand, changes of mood, which are accessory symptoms, often show a different picture which may perhaps be regarded as being due to the fact that monozygotic twins often differ in their respective temperaments. The course and severity of the disease also usually show considerable differences which may in part be due to additional affections.     

Differential diagnosis of malingering and factitious disorder with physical symptoms

The present article attempts to clarify the difficult diagnostic discrimination between malingering and factitious disorder with physical symptoms. It is proposed that diagnostic evaluations focusing on the patient's observed symptomatology will be limited in their accuracy and utility. Instead, a longitudinal approach is needed to include the course of the disorder over time, its response to treatment, and the proposed etiology of the disorder. It is hoped that with a better understanding of these two disorders, prompt and accurate diagnosis can lay the foundation for effective management of both malingering and factitious disorders.     

Determinants of tonic and phasic reactions in transswitching

Forty-eight college students were assigned randomly to four groups in a 2 × 2 factorial arrangement of phasic conditional stimuli (samevs. different) and tonic conditional stimuli (samevs. different) to receive 2 days of classical conditioning with a transswitching procedure. Tonic stimuli were a 5-minute projected white triangle or circle; phasic stimuli were a 5-second red or green square superimposed over the tonic stimuli. There were six tonic stimulus segments each day, separated by 20-second periods of no stimulus, three containing six trials of the phasic stimulus paired with shock and three containing six trials of the phasic stimulus alone, in the counterbalanced order. Tonic responding at the onset of the tonic stimuli or during brief periods following its onset were recorded, along with phasic responses to the phasic stimuli. Responses included magnitude of skin conductance responses, frequency of unelicited skin conductance responses, and tonic heart rate. Both skin conductance measures of responding to the tonic stimuli differentiated significantly between positive and negative tonic segments during Day 2, but only in the group with two different tonic stimuli and one phasic stimulus (“standard” transswitching). This supported the hypothesis that tonic stimulus differentiation would be absent when two different phasic stimuli were present. The heart rate data did not support this hypothesis, showing tonic differentiation in both groups with two tonic stimuli. Phasic differentiation controlled by the different phasic stimuli was observed on Day 1; on Day 2, phasic differentiation was present only in the group with two tonic and one phasic stimuli and the group with one tonic and two phasic stimuli. The results were interpreted to mean that temporal contiguity between the tonic stimuli and shock or no shock is not sufficient to establish tonic response differentiation in transswitching.     

Differential diagnosis between apraxia and dysarthria based on acoustic analysis

Acoustic analysis provides objective quantitative measures of speech that enable a comprehensive and accurate understanding of motor disorders and complement the traditional measures. This paper aims to distinguish between normal and pathological speech, more specifically between apraxia of speech and spastic dysarthria in native Spanish speaking patients using acoustic parameters. Participants (4 aphasic with apraxia of speech, 4 with spastic dysarthria, and 15 without speech disorders) performed three different tasks: repeating the syllable sequence [pa-ta-ka], repeating the isolated syllable [pa] and repeating the vowel sequence [i-u]. The results showed that the normative values of motor control, in general, coincide with those obtained in previous research on native English speakers. They also show that damage to motor control processes results in a decrease in the rate of alternating and sequential movements and an increase in the inter-syllabic time for both types of movements. A subset of the acoustic parameters analyzed, those that measure motor planning processes, enable differentiation between normal population and apraxic and dysarthric patients, and between the latter. The differences between the pathological groups support the distinction between motor planning and motor programming as described by van der Merwe's model of sensorimotor processing (1997).     

Karl Bonhoeffer and the concept of symptomatic psychoses

Against the background of the lifetime of Karl Bonhoeffer, March 31, 1868 to December 4, 1948, and the eighty-year-old concept of symptomatic psychoses, a sketch of the latter is set out and its present significance in symptomatology and research followed up.     

Bipolarity, monopolarity and "dichotomous functional decay" as principles of differential diagnosis and "functional pathology" of endogenous psychoses

On the basis of Leonhard's Classification of the endogenous psychoses an attempt is made to trace the phenomenology of the monopolar and bipolar affective psychoses as well as Leonhard's "unsystematic schizophrenias" to three different functional anomalies. The differential diagnosis between the "cycloid psychoses" and the "unsystematic schizophrenias" as well as the problem of the so-called schizoaffective psychoses connected with them, is of particular interest. The arrangement to "functional areas" seems to be suitable.