Disclosing individual genetic results to research participants

Investigators and institutional review boards should integrate plans about the appropriate disclosure of individual genetic results when designing research studies. The ethical principles of beneficence, respect, reciprocity, and justice provide justification for routinely offering certain results to research participants. We propose a result-evaluation approach that assesses the expected information and the context of the study in order to decide whether results should be offered. According to this approach, the analytic validity and the clinical utility of a specific result determine whether it should be offered routinely. Different results may therefore require different decisions even within the same study. We argue that the threshold of clinical utility for disclosing a result in a research study should be lower than the threshold used for clinical use of the same result. The personal meaning of a result provides additional criteria for evaluation. Finally, the context of the study allows for a more nuanced analysis by addressing the investigators' capabilities for appropriate disclosure, participants' alternative access to the result, and their relationship with the investigators. This analysis shows that the same result may require different decisions in different contexts.     

Autism: from research to practice

Autism is the most commonly studied of a spectrum of developmental disorders that are believed to be neurobiologically based but which, at this point, for lack of good biomarkers, are defined purely by behavior. In the last 20 years, the definition of autism has shifted in emphasis from extreme aloofness and positive signs of abnormality in repetitive and sensorimotor behaviors to a greater awareness of the importance of more subtle reciprocal social communication deficits as core features. Standard diagnostic instruments were developed for research purposes to acquire information both through caregiver interviews and direct clinical observation. Use of these instruments in clinical practice resulted in major improvements, which in turn affected research results. These results yielded further improvements that led to changes in clinical practice over time. The synergism between research and clinical practice in the understanding of autism is discussed.     

Applied orienting response research: Some examples

The development of orienting response (OR) theory has not been accompanied by many applications of the concept—most research still appears to be lab-based and “pure,” rather than “applied.” We present some examples from our own work in which the OR perspective has been applied in a wider context. These cover the exploration of processing deficits in autistic children, aspects of the “repression” of anxiety in elite athletes, and the locus of alcohol effects. Such applications of the OR concept in real-life situations seem a logical and, indeed,necessary step in the evolution of this area of psychophysiology. With a Comment by E. N. Sokolov     

Embracing complexity in research on learning from examples and from problem solving

This contribution is a commentary to a special issue titled “Example-based learning: New theoretical perspectives and advances to a contemporary instructional approach” published in Applied Cognitive Psychology (2020). In the commentary, the presented research is discussed with respect to three extensions compared with previous research, namely, theoretical frameworks, learning scenarios and domains. It concludes with some suggestions for methodological advancements.     

The practice research network: Research into practice,practice into research

The purpose of the broader project on which this report is based was to utilize a Practice Research Network, an alternative to traditional clinical studies to 1) identify demographically one practice group, namely professional counselors in the United States, 2) describe their practice patterns, and 3) identify their client population and the efficacy of their clinical work through client outcomes based on actual client reports. This article describes the development of one such nation‐wide Practice Research Network (PRN) and provides some preliminary findings for each phase of the project. Use of the PRN model can help overcome the traditional “research to practice” gap and provide research results into community practice thus integrating outcomes measures into the daily practice of mental health professionals. During the early phases of this project, a software program was developed upon which the participating practitioners could identify the data elements within the parameters of the focus on their agreed‐upon research interests, enter data following client visits over time, and by comparing their own composite profiles and effectiveness with those of other participating practitioners who had clients presenting with similar diagnoses, could alter their own service delivery patterns, therapeutic interventions, or approaches while working with the clients and thereby improve the efficacy of their service. By participating, the practitioners benefited by access to downloadable and printable reports on profiles of 1) their specific clients, 2) their service delivery patterns, and 3) the outcomes or efficacy by their clients’ direct feedback. They were also able to compare these results with the composite data from other practitioners.     

Microcontrolled stepping motors in behavior research: Two application examples

An inexpensive microprocessor-based motor controller is described. Two examples of research applications are discussed, and a listing of a motor control program is included. Some comparisons are made between the conventional methods of laboratory motion control and the microcontrolled stepping motor approach.     

Developmental phenomenology: examples from social cognition

Continental Philosophy Review - We explore relationships between phenomenology and developmental psychology through an in-depth analysis of a particular problem in social cognition: the most...     

Brief therapy in adult psychiatry: results from fifteen years of practice

We report the outcomes from our solution-focused brief therapy outpatient clinic in adult mental health. A questionnaire was sent to clients and their family doctors one year after they ceased to attend. Seventy-five clients were referred, of whom fifty-three were seen and forty-one traced at follow-up. Thirty-one (76%) reported a good outcome, with an overall average of 5.02 sessions, 20% attending only one session. Combining these data with our previous studies, 170 referrals were received of whom 136 attended and 118 were traced. Good outcome was reported by eighty-three clients (70%) with a mean of 4.03 sessions per case. There was no significant difference between the groups in solving additional problems or seeking further professional help. New problems were significantly less common in the 'good outcome' group. Long-standing problems did less well. In all three studies there were no significant differences in outcome between socioeconomic groups.     

Regression away from the mean: Theory and examples

Using a standard repeated measures model with arbitrary true score distribution and normal error variables, we present some fundamental closed-form results which explicitly indicate the conditions under which regression effects towards (RTM) and away from the mean are expected. Specifically, we show that for skewed and bimodal distributions many or even most cases will show a regression effect that is in expectation away from the mean, or that is not just towards but actually beyond the mean. We illustrate our results in quantitative detail with typical examples from experimental and biometric applications, which exhibit a clear regression away from the mean (‘egression from the mean’) signature. We aim not to repeal cautionary advice against potential RTM effects, but to present a balanced view of regression effects, based on a clear identification of the conditions governing the form that regression effects take in repeated measures designs.     

Measurement of individual differences: lessons from memory assessment in research and clinical practice

An examination of test manuals and published research indicates that widely used memory tests (e.g., Verbal Paired Associates and Word List tests of the Wechsler Memory Scale, Rey Auditory Verbal Learning Test, and California Verbal Learning Test) are afflicted by severe ceiling effects. In the present study, the true extent of memory ability in healthy young adults was tested by giving 208 college undergraduates verbal paired-associate and verbal learning tests of various lengths; the findings demonstrate that healthy adults can remember much more than is suggested by the normative data for the memory tests just mentioned. The findings highlight the adverse effects of low ceilings in memory assessment and underscore the severe consequences of ceiling effects on score distributions, means, standard deviations, and all variability-dependent indices, such as reliability, validity, and correlations with other tests. The article discusses the optimal test lengths for verbal paired-associate and verbal list-learning tests, shows how to identify ceiling-afflicted data in published research, and explains how proper attention to this phenomenon can improve future research and clinical practice.     

Reflexive action research: Developing knowledge through practice

This paper gives an overview of different ways of conducting counselling and psychotherapy research. An approach to research is described which overcomes the research‐practice gap: reflexive action research. It is argued that this approach to research is particularly appropriate and relevant for practitioners since it draws upon skills and awareness necessary for clinical work, and can complement positivist methods of research which are already well established in the profession. The wider use of systematic clinical case studies is suggested as a means of promoting the reflexive action research approach. Further consideration of issues of validity and reliability is required on the part of those intending to apply this approach within the field of therapy research.     

Attachment theory and systemic practice: research update

Attachment theory offers a way of thinking about the dyadic relationships within the family system. Family systems theory and therapy can contribute to attachment theory, as dyadic relationships do not exist in isolation but within the context of other relationships. Research at the interface between systemic practice and attachment theory is reviewed with examination of the central role they may play together in the developing understanding of family relationships.