Structural Stability within the Lateral Cerebellar Nucleus of the Rat Following Complex Motor Learning

Complex motor learning, but not mere motor activity, has been previously shown to induce structural modifications within the cerebellar cortex. The present experiment examined whether similar changes occur within one of the primary output targets of the region of the cerebellar cortex in which these structural changes were described, the lateral cerebellar nucleus (LCN; dentate nucleus). Adult female rats were randomly allocated to one of three training conditions. Acrobatic condition (AC) rats were trained to complete a complex motor learning task consisting of a series of elevated obstacles while motor control (MC) condition animals were forced to traverse a flat obstacle-free runway equal in length to the AC task. Inactive condition (IC) animals received no motor training. Unbiased stereological techniques and electron microscopy were used to obtain estimates of synapse number and postsynaptic density (PSD) length within the LCN. Results showed that neither synapse number nor PSD length was significantly altered as a function of training condition. These results indicate that complex motor skill learning is associated with structural plasticity within the cerebellar cortex and with structural stability within the lateral cerebellar nucleus.     

Benefits of Blocked Over Serial Feedback on Complex Motor Skill Learning

The effects of blocked versus serial feedback (FB) on the learning of a complex motor skill-the production of slalom-type movements on a ski-simulator-were examined. FB was given about force onset, which is considered to be a measure of movement efficiency; relatively late force onsets characterize expert performance. One group of participants (blocked FB; n = 10) received FB about 1 foot per day; for example, for the right foot on Days 1 and 3 and for the left foot on Days 2 and 4. For another group (serial FB; n = 10), the foot about which FB was received was switched on consecutive trials on each of 4 days of practice. Learning was assessed on no-FB trials at the beginning of Days 2, 3, and 4, and on Day 5. Even though there were no differences between groups in force onset, the blocked FB group produced significantly larger movement amplitudes and higher movement frequencies than the serial FB group on the retention test on Day 5. Thus, contrary to the learning of more simple skills (e.g., T. D. Lee & H. Carnahan, 1990), constantly changing the movement component that FB is provided about did not seem to be beneficial for the learning of more complex skills. The findings add to the increasing evidence showing that practice variables that have been shown to enhance the learning of simple skills can actually be detrimental to the learning of complex skills.     

Effect of Analogy Instructions with an Internal Focus on Learning a Complex Motor Skill

This study examined the effects of an analogy in learning breaststroke swimming. Two groups of participants had 20 lessons on how to increase their stroke length. The participants in the experimental condition received an analogy with an internal focus of attention. Inter-limb coordination showed qualitative changes in this group: a greater increase in swimming efficiency (i.e., a coordination closer to anti-phase [?50° before learning and ?125° after] and a 10% decrease in the time spent in-phase). The findings showed that an internal focus of attention induced by analogy could be beneficial in improving the quality of inter-limb swimming coordination.     

Variability of Practice and Contextual Interference in Motor Skill Learning

The purpose of this study was to investigate whether learning benefits in multiple-task learning situations are a result of contextual interference or of schema enhancement related to the amount of variability in the practice session. Two experiments were designed that replicated and extended the experiment reported by Wulf and Schmidt (1988). In a 2 (same vs. different relative time) x 2 (blocked vs. random practice schedule) design, 48 right-handed subjects were randomly assigned to one of four experimental conditions. A tapping task was employed that required a right-handed tap of three small brass plates arranged in a diamond pattern. Each segment had a specific time requirement. Target times and response times were provided on a computer screen directly in front of the subject. Each subject participated in two acquisition sessions (i.e., 198 practice trials) and was tested for learning on several different retention and transfer tests. In Experiment 2, a control group was added that received no acquisition phase. Results of both experiments showed a typical contextual interference effect, with depressed scores by the random groups during acquisition but significantly better scores than the blocked groups on several retention and transfer tests. Certain characteristics of the tests were found to influence the demonstration of the practice schedule effects. These results were consistent with predictions from Magill and Hall (1990) that the learning benefits of contextual interference are more likely to occur when skill variations are from different classes of movement and that the amount of variability in practice is more influential when the to-be-learned tasks are parameter modifications of the same generalized motor program.     

Dependence on Visual Feedback During Motor Skill Learning in Alzheimer's Disease

Three experiments examined the role of visual feedback on the performance of a fine motor task, namely the rotary pursuit, in patients with Alzheimer's disease (AD) and healthy older adults. After extensive practice tracking a fully visible target, participants in Experiments 1 and 2 were tested under restricted vision (RV) conditions. In both experiments, the two groups showed a drop in performance when vision was restricted, with AD patients showing a significantly larger decline. Tracking improved significantly in normal controls, but not AD patients across the RV trials after the initial drop. When difficulty of the rotary pursuit task was manipulated in Experiment 3 without restricting vision, AD patients and normal controls showed identical patterns of performance. Consequently, it could be concluded that AD patients in the first two experiments were relying more heavily on visual information for accurate performance of the tracking task than their healthy peers.     

干扰情境下类比习得运动技能的稳定性表现

本实验以高尔夫推杆技能学习为任务,采用双因素混合设计,通过对24名高尔夫新手的研究比较了类比和外显两种学习方式获得的运动技能在干扰情境下的操作表现。结果发现:(1)类比学习和外显学习在运动技能形成过程中的效果是相当的;(2)类比学习获得的运动技能在干扰情境下操作表现稳定,而外显学习获得的运动技能表现却下降。类比学习是一种具有实践应用价值的内隐学习方法。     

Neurocognitive Contributions to Motor Skill Learning: The Role of Working Memory

ABSTRACT

Researchers have begun to delineate the precise nature and neural correlates of the cognitive processes that contribute to motor skill learning. The authors review recent work from their laboratory designed to further understand the neurocognitive mechanisms of skill acquisition. The authors have demonstrated an important role for spatial working memory in 2 different types of motor skill learning, sensorimotor adaptation and motor sequence learning. They have shown that individual differences in spatial working memory capacity predict the rate of motor learning for sensorimotor adaptation and motor sequence learning, and have also reported neural overlap between a spatial working memory task and the early, but not late, stages of adaptation, particularly in the right dorsolateral prefrontal cortex and bilateral inferior parietal lobules. The authors propose that spatial working memory is relied on for processing motor error information to update motor control for subsequent actions. Further, they suggest that working memory is relied on during learning new action sequences for chunking individual action elements together.     

Signaling Mechanisms Mediating BDNF Modulation of Synaptic Plasticity in the Hippocampus

Although recent studies indicate that brain-derived neurotrophic factor (BDNF) plays an important role in hippocampal synaptic plasticity, the underlying signaling mechanisms remain largely unknown. Here, we have characterized the signaling events that mediate the BDNF modulation of high-frequency synaptic transmission. Mitogen-associated protein kinase (MAPK), phosphotidylinositol-3 kinase (PI3K), and phospholipase C-γ (PLC-γ) are the three signaling pathways known to mediate neurotrophin signaling in other systems. In neonatal hippocampal slices, application of BDNF rapidly activated MAPK and PI3K but not PLC-γ. BDNF greatly attenuated synaptic fatigue at CA1 synapses induced by a train of high-frequency, tetanic stimulation (HFS). Inhibition of the MAPK and PI3K, but not PLC-γ, prevented the BDNF modulation of high-frequency synaptic transmission. Neurotrophin-3 (NT-3), a close relative of BDNF, did not activate MAPK or PI3K and had no effect on synaptic fatigue in the neonatal hippocampus. Neither forskolin, which activated MAPK but not PI3 kinase, nor ciliary neurotrophic factor (CNTF), which activated PI3K but not MAPK, affected HFS-induced synaptic fatigue. Treatment of the slices with forskolin together with CNTF still had no effect on synaptic fatigue. Thus, although the activation of MAPK and PI3K is required, the two together are not sufficient to mediate the BDNF effect. Inhibition of new protein synthesis by anisomycin or cycloheximide did not prevent the BDNF effect. These data suggest that BDNF modulation of high-frequency transmission is independent of protein synthesis but requires MAPK and PI3K and yet another signaling pathway to act together in the hippocampus.     

Self-Regulated Learning of a Motor Skill Through Emulation and Self-Control Levels in a Physical Education Setting

This study examined the effectiveness of the second and third level of Zimmerman's (2000) model of self-regulated learning development. Participants were 72 (28 boys and 44 girls) fifth- and sixth-grade students who practiced the novel task of dart-throwing. Results showed that sixth-grade Greek students who proceeded sequentially from the emulation to the self-control level improved their dart-throwing performance more than students who missed one or both of these levels, but fifth-grade students benefited equally either from the sequential practice at the emulation and the self-control level or from the experience at one of these self-regulatory levels. No differences were found in self-efficacy, although sixth-grade students who practiced at the emulation level reported higher satisfaction, and sixth-grade students who practiced at the self-control level reported higher intrinsic motivation compared to control group students. These results attest to the effectiveness of learning at the emulation and self-control levels and are discussed with reference to the social cognitive model of self-regulation development.     

汉字输入中认知技能与动作技能的分离

通过20名大学生在采用目光注视屏幕上的键盘完成汉字输入任务的眼动研究,将汉字输入中的认知技能与动作技能实现分离,从而探究关于键盘布局图式的认知技能的发展.结果发现:(1)在标准键盘显示下,汉字输入技能水平高分组与低分组在完成时间上没有显著差异,而空白键盘显示下高分组的完成时间显著快于低分组;(2)两种键盘显示方式下,低分组的眼动指标都没有显著差异,而高分组在空白键盘显示下的平均注视时间要显著多于标准键盘显示下的.     

Influence of Expertise on the Intentional Transfer of Motor Skill

Intentional transfer of expert knowledge is an important issue in cognitive science and motor skills. How subjects deliberately transfer expertise in karate when learning a closely related motor skill (tai chi) was examined in this study. Subjects (N = 20) learned a videotaped sequence of self-defense movements, evaluated their learning, and then performed the sequence. Self-regulation of learning is believed to be central to effective transfer. The measures of self-regulation were accuracy of self-evaluation, video use, and approach to learning. Results showed that unlike novices, experts used self-regulation, learning strategies, and the video player in more complex ways in self-regulation. Experts, as compared with novices, demonstrated their greater knowledge through the higher quality of their performance and their better comprehension of movement meaning; but both groups recalled an equal number of moments, suggesting that both experts and novices transferred general knowledge about learning.     

The Role of Task Experience and Prior Knowledge for Detecting Invalid Augmented Feedback while Learning a Motor Skill

Two hypotheses were investigated. These were generated from results reported by Buekers, Magill, and Sneyers (1994) and an uncertainty account of those and other effects on skill learning of erroneous knowledge of results (KR). The first hypothesis proposes that if experienced performers have developed the capability of detecting and correcting errors, then they should not be influenced by erroneous KR in the same way as novices. The second proposes that if information about the invalid feedback is given to subjects prior to the beginning of the practice trials, then the capability for assessing feedback can be accelerated such that subjects who receive this advance information should not be misled by the erroneous KR. The first hypothesis was investigated in Experiment 1 by having subjects practise an anticipation timing task for 450 trials. One group received correct KR on all trials, and another group received no KR. Half of the subjects in each group were unexpectedly switched to erroneous KR after 400 trials. Results indicated that the erroneous KR influenced both groups during acquisition and on a retention test one minute later. However, on a retention test given one week later, only the group that had practised with no KR before being switched to erroneous KR continued to show the negative influence of the invalid KR. The second hypothesis was examined in Experiment 2 by telling subjects prior to beginning practice trials that it was possible that the KR they received would be erroneous. Results showed that this intervention strategy was effective on the no-KR retention tests only for subjects who had no-KR trials alternated with trials on which they received the erroneous KR. The results of these experiments provide evidence that uncertainty about the validity of sensory feedback increases the likelihood that subjects will be misled by invalid augmented feedback. Moreover, this uncertainty can be overcome by increased experience or by providing advance knowledge about the nature of the invalid feedback.     

Bilateral Transcranial Direct Stimulation Over the Primary Motor Cortex Alters Motor Modularity of Multiple Muscles

Abstract

Transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) has been demonstrated to modulate the motor performance of both healthy individuals and patients with neuromuscular disorders. However, the effect of tDCS on motor control of multiple muscles, which is a prerequisite to change in motor performance, is currently unknown. Using dimensionality reduction analysis, we investigated whether bilateral tDCS over M1 modulates the coordinated activity of 12 muscles. Fifteen healthy men participated in this randomized, double-blind crossover study. Each participant received a 20-min sham and 2-mA stimulation bilaterally over M1 (anode on the right M1 and cathode on the left M1), with a minimum washout period of 4?days. Muscle activation and end-point kinematics were evaluated during a task where participants reached out to a marked target with non-dominant hand as fast as possible, before and immediately after tDCS application. We found decreased similarity in motor modularity and significant changes in muscle activation in a specific motor module, particularly when reaching out to a target placed within arm’s length and improved smoothness index of movement only following 2-mA stimulation. These findings indicate that clinicians and researchers need to consider the simultaneous effect of bilateral tDCS over M1 on multiple muscles when they establish tDCS protocol to change in motor performance of patients with neuromuscular deficits.     

The Effects of Acute Aerobic Exercise on the Primary Motor Cortex

ABSTRACT. The effect of aerobic exercise on primary motor cortical excitability is a relevant area of interest for both motor learning and motor rehabilitation. Transient excitability changes that may follow an exercise session are a necessary precursor to more lasting neuroplastic changes. While the number of studies is limited, research suggests that a session of aerobic exercise can create an ideal environment for the early induction of plasticity. Potential mechanisms include the upregulation of neurotransmitter activity, altered cerebral metabolism and cortisol levels, and increases in brain-derived neurotrophic factor. While there is considerable evidence that chronic physical activity positively impacts brain health and function, studies examining cortical excitability changes and motor performance after a single session of exercise are lacking. Further research is required to determine the clinical utility and feasibility of aerobic exercise.     

Acquiring a Novel Coordination Skill without Practicing the Correct Motor Commands

There is evidence that experience of the sensory consequences, in the absence of practice of the required motor commands, is sufficient to learn new bimanual coordination patterns. This was shown through improvements of an incongruent group who practiced a desired 30° phase offset between the limbs while 1 limb was weighted such that the desired phase relation was achieved when synchronous motor commands were sent to the limbs (P. Atchy-Delama, P. G. Zanone, C. E. Peper, & P. J. Beek, 2005). In addition to testing a similar incongruent and congruent group (i.e., no weight), the authors extended this experiment by removing visual feedback during practice and by including an auditory modeling and passive guidance group. All groups showed improvement, except for the modeling group. The passive guidance group made more errors in posttests than the congruent and incongruent groups. Only the congruent group increased the amount of time around 30° after practice. Active experience of the sensory consequences combined with practice sending appropriate motor commands is the most effective method for learning, even though strategic improvements can be attained without experience of the latter.     

Neural Substrates of Olfactory Discrimination Learning with Auditory Secondary Reinforcement. I. Contributions of the Basolateral Amygdaloid Complex and Orbitofrontal Cortex

The basolateral amygdaloid complex (BLA) and orbitofrontal cortex (OFC) share extensive reciprocal connections, and interactions between these regions likely contribute to both mnemonic and affective processes. The present study examined the potential differential contributions of the BLA and OFC to performance of an olfactory discrimination task that incorporates auditory conditioned reinforcement and to expression of immediate post-shock freezing behavior. Damage to the BLA had little effect on performance of the conditioned reinforcement task but abolished immediate post-shock freezing behavior. In contrast, damage to OFC resulted in both a mild but significant performance decrement in the conditioned reinforcement task and a significant attenuation of immediate post-shock freezing behavior. These findings suggest that immediate post-shock freezing behavior is likely critically dependent upon interactions between the BLA and OFC. However, although mnemonic processes underlying accurate performance of the conditioned reinforcement task might be supported by OFC in part, such processes are independent of either the BLA or interactions between these two regions.     

Multisensory Information in the Control of Complex Motor Actions

ABSTRACT— For many of the complex motor actions we perform, perceptual information is available from several different senses including vision, touch, hearing, and the vestibular system. Here I discuss the use of multisensory information for the control of motor action in three particular domains: aviation, sports, and driving. It is shown that performers in these domains use information from multiple senses—frequently with beneficial effects on performance but sometimes with dangerous consequences. Applied psychologists have taken advantage of our natural tendency to integrate sensory information by designing multimodal displays that compensate for situations in which information from one or more of our senses is unreliable or is unattended due to distraction.     

Cerebellar contributions to the perception of temporal cues within the speech and nonspeech domain

A previous study (Ackermann, Gr?ber, Hertrich, & Daum, 1997) reported impaired phoneme identification in cerebellar disorders, provided that categorization depended on temporal cues. In order to further clarify the underlying mechanism of the observed deficit, the present study performed a discrimination and identification task in cerebellar patients using two-tone sequences of variable pause length. Cerebellar dysfunctions were found to compromise the discrimination of time intervals extending in duration from 10 to 150 ms, a range covering the length of acoustic speech segments. In contrast, categorization of the same stimuli as a "short" or "long pause" turned out to be unimpaired. These findings, along with the data of the previous investigation, indicate, first, that the cerebellum participates in the perceptual processing of speech and nonspeech stimuli and, second, that this organ might act as a back-up mechanism, extending the storage capacities of the "auditory analyzer" extracting temporal cues from acoustic signals.     

技能学习与重复启动基本机制问题的探讨

关于技能学习与重复启动的基本机制问题在学术界存有很大的争议．对其进行探讨将会对从整体上考察程序性记忆的性质产生重要的影响。此文主要从函数形式、相关性和增减模式的理论分析,数字输入任务的计算模型．程序性记忆和学习的观点几个方面探讨了有关问题,说明技能学习与重复启动是程序性记忆的不同表现形式,它们有着相同的基本机制。