目标刺激运动特征对自闭症谱系障碍儿童平滑追踪眼动的影响

选取3~5岁自闭症谱系障碍儿童(Autism Spectrum Disorder,ASD)与正常儿童各18名,采集其观看目标刺激沿不同垂直幅度、水平速度正弦曲线运动视频的眼动数据,考察振幅、速度等目标运动特征对被试平滑追踪眼动的影响。结果发现:(1)ASD儿童平滑追踪目标刺激的视觉位置误差显著大于正常儿童,其追踪目标的眼动轨迹不如正常组儿童平滑均匀,平滑追踪眼动存在明显不足。(2)正常儿童追踪目标刺激大振幅运行的位置误差显著大于小振幅运行条件,但ASD儿童却与之相反。(3)与正常儿童一样,目标刺激运行速度越快,ASD儿童平滑追踪的位置误差越大。总之,ASD儿童存在平滑追踪能力的不足;相比追踪大振幅运动的目标,ASD儿童追踪小振幅运动目标的能力更差。     

条件性恐惧泛化的性别差异

恐惧的过度泛化是焦虑障碍的核心症状之一, 表现为患者对与原危险刺激极不相似的中性刺激也有着较高强度的恐惧反应。临床上, 女性比男性更有可能患焦虑障碍, 因而对恐惧泛化进行性别差异研究可以为解释女性有着更高焦虑障碍发病率提供新的角度, 同时为临床治疗提供参考。本研究采用辨别性条件恐惧范式, 以主观预期值和皮电反应值作为测量指标, 从行为和生理两个层面对条件性恐惧泛化程度和恐惧泛化消退的性别差异进行研究。结果发现, 在恐惧泛化程度上, 未出现显著性别差异。在恐惧泛化消退上, 在主观预期值和皮电反应值两个层面均有着显著性别差异, 具体表现为相较于男性, 女性恐惧泛化的消退更慢, 持续时间更长。研究结果表明, 女性焦虑障碍高发病率的潜在影响因素之一可能在于女性对于恐惧泛化刺激的难以消除。     

状态焦虑对条件恐惧习得和消退的影响

采用44名正常女性大学生作为被试, 通过心理社会压力暴露的方法诱发焦虑组被试的状态焦虑, 采用主观预期值作为指标, 考察焦虑对条件恐惧习得和消退的直接影响, 并探讨这种影响是否也表现在评价性条件作用上。结果表明：心理社会压力暴露显著提高了焦虑组被试的状态焦虑。在习得阶段, 状态焦虑降低了被试对条件刺激的辨别条件恐惧反应, 具体而言, 状态焦虑降低了被试对CS+的主观预期值, 但是却提高了对CS?的主观预期值; 在消退阶段, 状态焦虑抑制了被试对条件刺激的消退。状态焦虑的影响也表现在评价性条件作用上, 和控制组相比, 焦虑组在习惯化和消退阶段对条件刺激表现出了更为负性的效价评定。     

5～7岁自闭症谱系障碍儿童环境文字阅读的特点

以带有不同类型情境线索(包括颜色、图标和字体)的环境文字为材料,采用命名任务考察5～7岁28名自闭症谱系障碍儿童和30名正常儿童阅读环境文字的特点。结果发现:(1)在去掉环境文字中的图标后,自闭症谱系障碍儿童和正常儿童命名文字的得分都显著降低;(2)在消除环境文字的字体线索后,自闭症谱系障碍儿童命名文字的得分显著降低,但正常儿童却较少受影响;(3)在阅读环境文字时,无论是自闭症谱系障碍儿童还是正常儿童,识字量越多,儿童越少依赖图标线索的提示。这些结果表明,自闭症谱系障碍儿童在阅读环境文字时,受图标线索和字体线索的影响较大,为制定促进其阅读学习的早期识字干预方案提供参考。     

汉语自闭症儿童分类能力的实验研究

为探查自闭症儿童的分类能力,采用类别判断任务,比较了刺激的典型性对12名汉语自闭症儿童和相匹配控制组儿童分类正确率和反应时的影响。研究发现,自闭症组在典型刺激上的分类能力与控制组大致相同,但在不典型刺激上的分类能力明显更差,表明自闭症儿童既有一定的分类能力,又存在内在的缺陷。研究结果支持自闭症"弱的中心统合理论"。     

汉语高功能自闭症儿童代词加工:利用提及顺序和重读线索的表现

采用句子理解任务分别探究了5~7岁的汉语高功能自闭症儿童在单独提及顺序线索,提及顺序线索和重读线索共现两种条件下代词加工的表现。研究结果表明,汉语高功能自闭症儿童不像智商和工作记忆广度匹配的同龄典型发展儿童一样能够单独利用提及顺序线索加工代词,即倾向于选择首先提及的实体作为代词的指称对象,而表现为随机选择代词所指。当提及顺序线索和重读线索共现时,典型发展儿童在两条线索一致和冲突时都倾向于依靠重读线索加工代词,而汉语高功能自闭症儿童对两条线索都不敏感,表现为随机选择代词所指。这表明5~7岁的汉语高功能儿童不能够利用这两条线索加工代词,在利用语篇突显性线索加工代词方面存在困难。     

表情强度对自闭症儿童面部表情识别影响的实验研究

为探寻自闭症儿童在识别低强度（10%,30%）、中强度（40%,60%）和高强度（70%,90%）的愤怒和开心面部表情时,识别情绪类型的既有能力和差异。采用表情标签范式,用E-prime软件在电脑上呈现不同强度的3D合成面部表情刺激,分别对10名自闭症儿童、10名正常发育儿童和10名智障儿童进行了实验研究。结果发现,自闭症儿童在低强度表情时具有面部表情识别障碍,其对不同强度面部表情识别正确率显著低于智障儿童和正常发育儿童;自闭症儿童面部表情识别正确率与面部表情强度呈正相关,面部表情强度越大,自闭症儿童面部表情识别的正确率越高;自闭症儿童对低强度面部表情识别时,对开心表情的识别正确率高于愤怒表情,但是,在中强度和高强度面部表情识别时,存在显著的愤怒优势效应。     

聋童执行功能发展：聋童与正常儿童的比较

利用标准Dimensional Change Card Sort任务(DCCS),对76名智力正常的3~8岁聋童和78名3~5.5岁的正常儿童进行了对比测试,旨在考察聋童执行功能发展的年龄特征与发展水平。结果发现,3岁组的聋童和正常儿童在DCCS任务上的表现没有显著性差异,但正常儿童在4~4.5岁时进入一个迅速发展期,而聋童要在6岁时才有快速的发展,到7岁后才相当于正常儿童5岁的发展水平,大约滞后2年。研究认为,造成聋童执行功能发展滞后的原因主要有：（1）语言符号系统和聋童特有的符号系统之间可能存在的差异;（2）聋童可能存在计划和灵活性的缺陷;（3）聋童可能存在命名和标识策略上的困难和注意机制的缺陷。结合关于聋童心理理论发展滞后于正常儿童7年以上的报道,心理理论发展和执行功能发展在聋童身上表现出较大的不一致性。     

儿童在不同卷入情境下基于资源价值的分配行为特点：内群体偏爱的作用

为探究不同卷入情境下儿童基于资源价值的分配行为特点以及内群体偏爱在其中的作用, 呈现给儿童两种实验情境：实验1, 134名5~8岁儿童在第一方情境下与来自内、外群体的一名儿童分配不同价值的物品, 结果发现7~8岁儿童公平分配比例与5~6岁儿童无显著差异; 实验2, 130名5~8岁儿童在第三方情境下给来自特定群体的两名儿童分配资源, 结果发现7~8岁儿童公平分配比例显著高于5~6岁儿童。两个实验均发现儿童的分配行为表现出内群体偏爱, 5~6岁儿童比7~8岁儿童更明显。并且, 5~6岁女生比男生有更明显的内群体偏爱, 但在7~8岁组无性别差异。此外, 只有7~8岁儿童的公平分配行为表现出卷入情境上的差异, 他们在第三方情境比第一方情境下更能做出公平分配, 但5~6岁儿童的公平分配行为并无情境差异。综上可见, 比起年幼儿童, 年长儿童基于资源价值的公平行为发展得更好, 并且在两种卷入情境下受内群体偏爱的影响均更小。     

7～10岁自闭症谱系障碍儿童对情绪面孔的觉察与加工

为了考察自闭症谱系障碍(autism spectrum disorder,ASD)儿童对不同情绪面孔的觉察和加工情况,设计两个眼动实验任务,要求14名7～10岁ASD儿童和20名同年龄正常儿童观看图片。实验一采用将情绪面孔嵌入风景图片中引起语义不一致的刺激;实验二采用含有情绪面孔的无意义背景乱序图片刺激。结果发现:(1)ASD儿童对不同情绪面孔的觉察时间都显著长于正常儿童;(2)与正常儿童一样,ASD儿童表现出对恐惧面孔的注意偏向;(3)实验二中,ASD儿童对不同情绪面孔内部特征区的注意分配与正常儿童不同;正常儿童能注意最能展示该类情绪特征信息的区域,如恐惧的眼睛、愉快的嘴巴,而ASD儿童对三类情绪面孔特征区的注意分配方式相似;(4)两个实验条件下,ASD者对不同情绪面孔的觉察、加工模式与正常儿童相似。     

The use of an unpleasant sound as the unconditional stimulus in aversive Pavlovian conditioning experiments that involve children and adolescent participants

Ethical considerations can prohibit the use of traditional unconditional stimuli (USs), such as electric shocks or loud tones, when children or adolescents participate in aversive Pavlovian conditioning experiments. The present study evaluated whether an unpleasant sound provides a viable alternative. Fifteen boys and girls aged 13 to 17 years completed a differential Pavlovian conditioning procedure in which a conditional stimulus (CS) was followed by the sound of metal scraping on slate. Acquisition of conditioned responses was found in startle blink magnitude, expectancy judgments of the sound, and skin conductance responses. Extinction of conditioned responses was found in all measures when the CS was no longer followed by the unpleasant sound. Subjective ratings and skin conductance responses indicated that the sound was unpleasant because of its qualitative features, rather than its intensity. The results support the use of an unpleasant sound as a low-risk alternative to traditional USs in aversive Pavlovian conditioning experiments with children and adolescents.     

Learning history in fear of blushing

Two studies, investigating the learning history (i.e. traumatic conditioning experiences, vicarious learning, informational learning) of individuals with and without fear of blushing, are presented. In study 1, individuals high (n=61) and low (n=59) in fear of blushing completed the (revised) Phobic Origin Questionnaire [POQ; Öst, L. G., & Hugdahl, K. (1981). Acquisition of phobias and anxiety response patterns in clinical patients. Behavior Research and Therapy, 19, 439–447]. In study 2, individuals who applied for treatment for fear of blushing (n=31) and a nonfearful, matched control group (n=31) were interviewed with the same instrument, taking into account only specific memories. High fearful individuals reported more negative learning experiences in connection with blushing than low fearful individuals, irrespective of the type of questioning. Meanwhile, study 1 (written POQ) produced higher percentages of negative learning experiences for both high and low fearful individuals than study 2 (interview). It is concluded that the POQ interview showed a more realistic picture than the written POQ. The possible role of learning history in the acquisition of fear of blushing is discussed.     

自闭症谱系障碍儿童在多重线索下习得词语的眼动研究

本文利用眼动追踪技术在基线、一致和矛盾3种实验条件下考察感知觉线索和社会性线索在自闭症谱系障碍儿童词语习得中的相对作用。行为数据结果表明, 此类儿童在矛盾条件下选择枯燥物体作为新异词语的所指对象, 这说明社会性线索较之于感知觉线索具有优势作用; 而他们在基线和一致条件下选择有趣物体作为新异词语的所指对象, 且一致条件的词语习得成绩优于基线条件, 这说明社会性线索较之于感知觉线索具有促进作用。眼动数据结果表明, 此类儿童在脸部注视模式和视线追随行为上与普通儿童存在差异。这说明, 虽然社会性线索在此类儿童与普通儿童的词语习得中具有相同的相对作用, 但他们获取社会性信息的方式与普通儿童存在差异。     

Semantic richness and word learning in children with autism spectrum disorder

Semantically rich learning contexts facilitate semantic, phonological, and articulatory aspects of word learning in children with typical development (TD). However, because children with autism spectrum disorder (ASD) show differences at each of these processing levels, it is unclear whether they will benefit from semantic cues in the same manner as their typical peers. The goal of this study was to track how the inclusion of rich, sparse, or no semantic cues influences semantic, phonological, and articulatory aspects of word learning in children with ASD and TD over time. Twenty‐four school‐aged children (12 in each group), matched on expressive vocabulary, participated in an extended word learning paradigm. Performance on five measures of learning (referent identification, confrontation naming, defining, phonetic accuracy, and speech motor stability) were tracked across three sessions approximately one week apart to assess the influence of semantic richness on extended learning. Results indicate that children with ASD benefit from semantically rich learning contexts similarly to their peers with TD; however, one key difference between the two groups emerged – the children with ASD showed heightened shifts in speech motor stability. These findings offer insights into common learning mechanisms in children with ASD and TD, as well as pointing to a potentially distinct speech motor learning trajectory in children with ASD, providing a window into the emergence of stereotypic vocalizations in these children.     

Aversive conditioning under conditions of restricted awareness: Effects on spatial cueing

In the literature on aversive conditioning there is still debate on the role of awareness. According to some authors, affective learning can occur with or without contingency learning (dual-process model), whereas others argue that a single process produces both affective responses and contingency knowledge. Although many studies have investigated these models, the results to date are inconclusive. Based on a review of the literature, a new series of experiments was designed to examine aversive conditioning in the absence of contingency awareness. In the present study we examined the effects of subliminal aversive conditioning on a spatial cueing task. Awareness was stringently tested after conditioning. Three kinds of awareness were distinguished: contingency awareness (awareness of the CS?US contingencies, where CS is the conditioned stimulus, and US is the unconditioned stimulus), perceptual awareness (awareness of the perceptual differences between the CSs), and US expectancy (awareness of a threat feeling when confronted with the CS+, but not when confronted with the CS?). The results of three experiments demonstrated that responses on the spatial cueing task were modulated by subliminal aversive conditioning. Importantly, none of the participants was contingency aware or able to perceptually discriminate between the conditioned stimuli. However, in Experiment 3, only those participants showing some level of postconditioning expectancy awareness exhibited conditioning effects. These experiments suggest that subliminal aversive conditioning produces small but significant effects, which may be modulated by expectancy awareness.     

Electrophysiological evidence of heterogeneity in visual statistical learning in young children with ASD

Statistical learning is characterized by detection of regularities in one's environment without an awareness or intention to learn, and it may play a critical role in language and social behavior. Accordingly, in this study we investigated the electrophysiological correlates of visual statistical learning in young children with autism spectrum disorder (ASD) using an event‐related potential shape learning paradigm, and we examined the relation between visual statistical learning and cognitive function. Compared to typically developing (TD) controls, the ASD group as a whole showed reduced evidence of learning as defined by N1 (early visual discrimination) and P300 (attention to novelty) components. Upon further analysis, in the ASD group there was a positive correlation between N1 amplitude difference and non‐verbal IQ, and a positive correlation between P300 amplitude difference and adaptive social function. Children with ASD and a high non‐verbal IQ and high adaptive social function demonstrated a distinctive pattern of learning. This is the first study to identify electrophysiological markers of visual statistical learning in children with ASD. Through this work we have demonstrated heterogeneity in statistical learning in ASD that maps onto non‐verbal cognition and adaptive social function.     

Atypicalities in sleep and semantic consolidation in autism

Sleep is known to support the neocortical consolidation of declarative memory, including the acquisition of new language. Autism spectrum disorder (ASD) is often characterized by both sleep and language learning difficulties, but few studies have explored a potential connection between the two. Here, 54 children with and without ASD (matched on age, nonverbal ability and vocabulary) were taught nine rare animal names (e.g., pipa). Memory was assessed via definitions, naming and speeded semantic decision tasks immediately after learning (pre‐sleep), the next day (post‐sleep, with a night of polysomnography between pre‐ and post‐sleep tests) and roughly 1 month later (follow‐up). Both groups showed comparable performance at pre‐test and similar levels of overnight change on all tasks; but at follow‐up children with ASD showed significantly greater forgetting of the unique features of the new animals (e.g., pipa is a flat frog). Children with ASD had significantly lower central non‐rapid eye movement (NREM) sigma power. Associations between spindle properties and overnight changes in speeded semantic decisions differed by group. For the TD group, spindle duration predicted overnight changes in responses to novel animals but not familiar animals, reinforcing a role for sleep in the stabilization of new semantic knowledge. For the ASD group, sigma power and spindle duration were associated with improvements in responses to novel and particularly familiar animals, perhaps reflecting more general sleep‐associated improvements in task performance. Plausibly, microstructural sleep atypicalities in children with ASD and differences in how information is prioritized for consolidation may lead to cumulative consolidation difficulties, compromising the quality of newly formed semantic representations in long‐term memory.     

5～7岁自闭症谱系障碍幼儿数感的特点

本研究采用《幼儿数感测评量表》对26名自闭症谱系障碍（autism spectrum disorders,ASD）幼儿、20名智力障碍幼儿及32名正常幼儿进行数感能力测评,并比较三组幼儿的数感特点。结果发现：（1）ASD幼儿的数感整体和各维度水平均显著低于正常幼儿,但与智力障碍幼儿相当;（2）三组幼儿数感各维度水平在5～7岁之间无明显变化;（3）三组幼儿在数量比较、数量估算和大小比较的能力水平均领先于其他维度,而类比推理和大小推理均相对落后。另外,ASD幼儿和智力障碍幼儿的体积比较与大小推理、类比推理的能力较为接近,而正常幼儿的体积比较能力显著优于大小推理和类比推理。研究表明5～7岁ASD幼儿的数感能力整体落后于同龄正常幼儿,且数感各维度的能力发展不均衡、不同步。本研究揭示了5～7岁ASD幼儿数感能力发展的特点及需求,可为制定相应数感干预方案、促进其数学学习提供参考。     

Learning new faces in typically developing children and children on the autistic spectrum

As faces become familiar, recognition becomes easier but the style of processing also changes. Here, twenty-one typically developing (TD) children and twenty-one children with autism spectrum disorder (ASD) were familiarised with 6 identities over 3 days. Next, they completed a 4-alternative forced-choice matching test in which targets were the 6 familiarised faces and 6 unfamiliar faces. The TD group showed a significant advantage for familiarised faces when matching whole faces and both internal and external facial regions. The ASD group showed similar familiarisation effects for whole and external faces, but not for internal regions. The ASD group was also impaired at matching eyes and mouths of familiarised faces. Results suggest the process of acquiring familiarity with faces differs from ASD and TD children.     

情绪学习促进无意识信息进入意识

采用突破连续闪烁抑制范式(b-CFS), 考察了经过情绪学习的刺激在无意识中是否存在加工优势。实验1使用不同朝向的光栅刺激, 结果发现情绪学习条件比对照条件的刺激在CFS中突破抑制时间更短。实验2考察了更复杂的朝向和颜色整合的光栅刺激, 发现情绪优势效应具有特异性, 仅局限于情绪学习的整合刺激。研究表明经过情绪学习后的刺激在无意识加工中存在优势。