In the best interests of the deceased: A possible justification for organ removal without consent?

Opt-out systems of postmortem organ procurement are often supposed to be justifiable by presumed consent, but this justification turns out to depend on a mistaken mental state conception of consent. A promising alternative justification appeals to the analogical situation that occurs when an emergency decision has to be made about medical treatment for a patient who is unable to give or withhold his consent. In such cases, the decision should be made in the best interests of the patient. The analogous suggestion to be considered, then, is, if the potential donor has not registered either his willingness or his refusal to donate, the probabilities that he would or would not have preferred the removal of his organs need to be weighed. And in some actual cases the probability of the first alternative may be greater. This article considers whether the analogy to which this argument appeals is cogent, and concludes that there are important differences between the emergency and the organ removal cases, both as regards the nature of the interests involved and the nature of the right not to be treated without one’s consent. Rather, if opt-out systems are to be justified, the needs of patients with organ failure and/or the possibility of tacit consent should be considered.     

Depression or anxiety: which is best able to predict patterns of lateralisation for the processing of emotional faces?

Previous research has shown that both anxiety and depression are associated with strength of lateralisation for the processing of emotive faces, although these clinical measures have always been considered in separate studies. In the present study, we measure depression and anxiety, within the same non-clinical sample, and consider whether these variables can predict strength of lateralisation, measured using the chimeric faces test. There are two key findings from this study. First, for females only, anxiety is negatively associated with right hemispheric superiority for processing of negative emotional expressions. Second, there was only one finding for depression, showing a relationship with strength of lateralisation for the processing of fearful faces that differed according to sex.     

Must the bearer of a right have the concept of that to which he has a right?

Stevens critiques what he calls the "conceptual possession requirement" as defined by Michael Tooley in his article, "Abortion and infanticide," Philosophy and Public Affairs 1972 Fall; 2(1): 37-65. Tooley argued that a being has a right to something only if it has the concept of that thing. He claimed that fetuses and infants do not have a serious right to life because they have no concept of a continuing self, and that therefore abortion and infanticide are morally permissible. Stevens contends that the conceptual possession requirement is not valid, offers a counterexample to Tooley's argument, and defends his reasoning against what he presumes might be Tooley's counterarguments.     

Resolving the paradox of common, harmful, heritable mental disorders: which evolutionary genetic models work best?

Given that natural selection is so powerful at optimizing complex adaptations, why does it seem unable to eliminate genes (susceptibility alleles) that predispose to common, harmful, heritable mental disorders, such as schizophrenia or bipolar disorder? We assess three leading explanations for this apparent paradox from evolutionary genetic theory: (1) ancestral neutrality (susceptibility alleles were not harmful among ancestors), (2) balancing selection (susceptibility alleles sometimes increased fitness), and (3) polygenic mutation-selection balance (mental disorders reflect the inevitable mutational load on the thousands of genes underlying human behavior). The first two explanations are commonly assumed in psychiatric genetics and Darwinian psychiatry, while mutation-selection has often been discounted. All three models can explain persistent genetic variance in some traits under some conditions, but the first two have serious problems in explaining human mental disorders. Ancestral neutrality fails to explain low mental disorder frequencies and requires implausibly small selection coefficients against mental disorders given the data on the reproductive costs and impairment of mental disorders. Balancing selection (including spatio-temporal variation in selection, heterozygote advantage, antagonistic pleiotropy, and frequency-dependent selection) tends to favor environmentally contingent adaptations (which would show no heritability) or high-frequency alleles (which psychiatric genetics would have already found). Only polygenic mutation-selection balance seems consistent with the data on mental disorder prevalence rates, fitness costs, the likely rarity of susceptibility alleles, and the increased risks of mental disorders with brain trauma, inbreeding, and paternal age. This evolutionary genetic framework for mental disorders has wide-ranging implications for psychology, psychiatry, behavior genetics, molecular genetics, and evolutionary approaches to studying human behavior.     

Pictures, words, and sounds: from which format are we best able to reason?

The effect of presentation format on reasoning was studied with a sentence verification task. Background information was presented in single-format and combined conditions that included pictured, printed, or spoken versions of the stimulus items. In Experiment 1, a test sentence appeared together with the background at varied stimulus onset asynchronies, to study how format influences the acquisition of the stimulus information. In Experiments 2 and 3, however, the test sentence followed the presentation of the background, to test the effect of format on memory. Reaction time responses to the test sentences showed a consistent picture advantage. However, when participants responded to materials stored in memory, both pictured and spoken formats provided quicker responses in comparison to printed words, and the format difference was smaller than when materials were readily available on the screen. Multimedia presentations, when compared with single-format conditions, did not provide additional benefits.     

Mirror,mirror on the wall,which form of narcissist knows self and others best of all?

We examined the relationships of narcissism and its various facets with measures of cognition, such as perspective-taking/theory of mind, emotional intelligence, empathy, and systemizing, in a non-clinical sample of 368 undergraduate students. Social and physical causal reasoning was assessed using a novel procedure, which allowed for a thorough examination of participants’ attributions of causes to social and non-social events. Results revealed that individuals high in grandiosity scored higher on measures of social reasoning, emotional intelligence, perspective-taking, systemizing, and empathy. Other facets of narcissism, as well as the overall construct of narcissism, were negatively associated with emotional intelligence, empathy, and perspective-taking. These results suggest that the facets of narcissism may differ considerably in their associations with various aspects of social cognition, which should prompt researchers to further examine the heterogeneous nature of narcissism.     

Motor programming: does the choice of the limb which is to carry out the response imply a delay?

In many activities, the human being must quickly decide on the response to be produced following a change in the environment. In some of these situations, the limb that the individual chooses to carry out a response seems to be a significant element in performance. Thus, if the individual carries out the response with the limb closest to the target, the performance can improve because it will take less time to achieve the goal. However, it seems that in these situations, the human being does not take this decrease in movement time into consideration and that the response is carried out with the dominant hand. Why is this so? It may be because the reaction is faster when there doesn't have to be a choice as to which limb will carry out the response. The goal of this study was to check this possibility. In order to do so, the subjects performed a two choice reaction-time task. For this task, some subjects knew beforehand which hand they had to use to carry out the response while other subjects were unaware of this fact. The results of two experiments indicated that the choice of the limb which is to carry out the response requires no particular delay when the movement to be produced is externally guided.     

We talk,therefore we think? A cultural analysis of the effect of talking on thinking

The Western assumption that talking is connected to thinking is not shared in the East. The research examines how the actual psychology of individuals reflects these different cultural assumptions. In Study 1, Asian Americans and European Americans thought aloud while solving reasoning problems. Talking impaired Asian Americans' performance but not that of European Americans. Study 2 showed that participants' beliefs about talking and thinking are correlated with how talking affects performance, and suggested that cultural difference in modes of thinking can explain the difference in the effect of talking. Study 3 showed that talking impaired Asian Americans' performance because they tend to use internal speech less than European Americans. Results illuminate the importance of cultural understanding of psychology for a multicultural society.     

A new vision of a classical question: How to become a mother?

Abstract

This article offers a reflection on conception, pregnancy, and the first mother–infant relationships of mothers with motoric and sensory disabilities. Based on more than 13 years of experience with women with motoric and sensory disabilities who had a desire for a child, the author analyzes this unusual situation from three different points of view: the medical help to procreate, meeting a partner for the mother, and the link with the initial maternal family, i.e. the mother’s mother. The last part concerns the possibility of the development of a mother–infant relationship when bodily function is lacking.     

Using a short form of the WISC-III: sinful or smart?

This article describes an example of making pediatric neuropsychological assessments more time-efficient. Empirical support, including new data, for the utilization of an eight-subtest short form of the Wechsler Intelligence Scale for Children-Third Edition (WISC-III; Wechsler, 1991) is reviewed. It is concluded that this short form of the WISC-III is a valid substitute for the complete version under most clinical circumstances, allowing the practitioner to expand on interview, history or more specific neuropsychological tests without adding financial or time burdens to the evaluation.     

Exemplarization: a solution to the problem of consciousness?

In recent publications, Keith Lehrer developed the intriguing idea of a special mental process??exemplarization??and applied it in a sophisticated manner to different phenomena such as intentionality, representation of the self, the knowledge of ineffable content (of art works) and the problem of phenomenal consciousness. In this paper I am primarily concerned with the latter issue. The target of this paper is to analyze whether exemplarization, besides explaining epistemic phenomena such as immediate and ineffable knowledge of experiences, can also solve the ontological problem of consciousness. In particular, Lehrer suggests that if we consider exemplarization, zombies cannot provide an argument for anti-physicalism. I argue that exemplarization offers neither a physicalist explanation of the conceivability of zombies nor an elucidating physicalist account of their impossibility. Therefore, exemplarization cannot offer a physicalist solution to the ??hard problem?? of consciousness.     

Time to retire the concept of brand personality? Extending the critique and introducing a new framework

In consumer behaviour literature, there is a growing concern about the construct validity of brand personality. We extend this critique and introduce a new approach for the conceptualisation and measurement of human brand associations (HBA). A qualitative study of free associations to six brands in different categories and cultures reveals that brand personality traits, as defined in the literature, are practically non‐existent in real associative networks for brands. The responses are, however, in line with the new HBA framework. The findings suggest that consumer researchers should retire the concept of brand personality and use the new approach instead.     

Commentaries on “Beyond statistical significance: Five principles for the new era of data analysis and reporting”

Three commentaries below provide different perspectives on data analysis and reporting. They generally focus on how the quality of the measures and manipulations determines the value of the analysis. Norbert Schwarz and Fritz Strack's comment is less on the right statistic and more on “sloppy reasoning, gaps between theoretical concepts and their operationalizations, and blissful ignorance of the situated nature of human thinking, feeling, and doing contribute more to the limited reproducibility of empirical findings than the choice of a particular test statistic.” They propose that particular effects are contextual and inappropriately labeled as true or false. Instead, our job is to focus on general constructs that make sense of the diversity of human experience and psychological reactions. Too often studies replicating psychological effects in the noisy and confounded conditions of the marketplace result in statistical uncertainty of garbage in, garbage out. Researchers instead need to look toward tests of specific interactions, which can clarify the influencing factors based on theoretical considerations. The second comment is by Andrew Gelman, an outstanding psychological statistician. He proposes that “once the data have been collected, the most important decisions have already been done.” He then provides four recommendations that enable the statistics to work appropriately. The first requirement of an effective study is to be sure that the measures address the construct of interest. Similar to the position of Schwarz and Strack, it is important to articulate the relevance of a statistically significant finding. The second recommendation seeks to curb large number of studies with inflated effect sizes built from narrow studies and unwarranted optimism. The third recommendation is to simulate data from a model and consider the distribution of possible results. That is often done to test a new analysis method, but it can be even more important in marketplace studies where novel characteristics of the sample and experimental conditions are included in the analysis. Finally, he recommends that one consider likely analyses needed before getting the data. Such foresight would encourage, for example, thinking about the kind of data needed to defend the equality of the control demographics against the treatment. The final commentary is by Stijn van Osselaer. He agrees that p-values reflect the detailed methods from a given study but do not focus on the problem of generalizability. Like Gelman, he sees designs focused on effect sizes may have generated too many studies that do not replicate. He contrasts broad explorations with narrowly defined existence tests that provide evidence that an effect exists somewhere but are mute on other contexts where they may apply. For theoretical problems relevant to applications, it is important to identify moderators through broad sampling across population characteristics, stimuli, and situations. He proposes that consumer psychologists should not try to do everything in one paper, but to build practically relevant, applicable knowledge across multiple articles. Different articles, authors, and research methods play various roles, with each article focusing on important stages in the process from generating hypotheses, providing existence proofs, and exploring their broad applicability. That pragmatic approach can integrate theoretical silos that seek to resolve complex human problems and has promise as a criterion for relevant publications.     

Youth and the Great Recession: Are values,achievement orientation and outlook to the future affected?

This special section brings together leading experts in psychology and sociology to examine the consequences of the Great Recession for young people's values, achievement orientation, and outlook to the future. Evidence from Europe and the United States suggests that the impact of the recession varies for distinct outcomes and by age, the latter pointing to potential sensitive periods for interventions. Although the direct effects of the recession are not strong, they accelerate pre‐existing trends towards more prolonged and precarious transitions to independence, and are likely to bring with them long‐term scarring with respect to health and well‐being. While feelings of self‐confidence and self‐worth have eroded, young people continue to subscribe to the “American Dream,” the belief that in principle it is possible to make it – even if limitations to one's own capabilities are recognised. Trust in institutions has declined, but support and concern for others have increased, suggesting that in times of economic hardship and uncertainty social relationships become more salient. Young people's response to the recession appears to be less of a “me‐first” reaction than “let's help each other”: a form of “collective agency” to counter the inadequacy of social safety nets.     

Reverse-engineering ‘esotericism': how to prepare a complex cultural concept for the cognitive science of religion

The article introduces a framework for preparing complex cultural concepts for the cognitive science of religion (CSR) and applies it to the field of Western esotericism. The research process (‘reverse engineering') rests on a building block approach that, after problematic categories have been deconstructed, seeks to reconstruct new scholarly objects in generic terms that can be operationalized in interdisciplinary contexts like CSR. A four-step research process is delineated, illustrated by a short discussion of previous work on ‘Gnosticism,' ‘magic,' and ‘religion,' before applying it to ‘esotericism.' It is suggested that the implicit scholarly objects of esotericism scholarship can be reconstituted in generic terms as concerned with processes of creating and disseminating ‘special knowledge.' Five definitional clusters are identified in the literature; these provide a basis for formulating research programs on the psychological and cognitive level, drawing on metarepresentational processes, event cognition, and psychological dispositions for altering experience.     

Trust and the collection,selection, analysis and interpretation of data: A scientist’s view

Trust is a critical component of research: trust in the work of co-workers and colleagues within the scientific community; trust in the work of research scientists by the non-research community. A wide range of factors, including internally and externally generated pressures and practical and personal limitations, affect the research process. The extent to which these factors are understood and appreciated influence the development of trust in scientific research findings.     

RNA interference: a new mechanism by which FMRP acts in the normal brain? What can Drosophila teach us?

Fragile X syndrome is the most common heritable form of mental retardation caused by loss-of-function mutations in the FMR1 gene. The FMR1 gene encodes an RNA-binding protein that associates with translating ribosomes and acts as a negative translational regulator. Recent work in Drosophila melanogaster has shown that the fly homolog of FMR1 (dFMR1) plays an important role in regulating neuronal morphology, which may underlie the observed deficits in behaviors of dFMR1 mutant flies. Biochemical analysis has revealed that dFMR1 forms a complex that includes ribosomal proteins and, surprisingly, Argonaute2 (AGO2), an essential component of the RNA-induced silencing complex (RISC) that mediates RNA interference (RNAi) in Drosophila. dFMR1 also associates with Dicer, another essential processing enzyme of the RNAi pathway. Moreover, both a micro-RNA (miRNA) and short interfering RNAs (siRNAs) can coimmunoprecipitate with dFMR1. Together these findings suggest that dFMR1 functions in an RNAi-related apparatus to regulate the expression of its target genes at the level of translation. These findings raise the possibility that Fragile X syndrome may be the result of a protein synthesis abnormality caused by a defect in an RNAi-related apparatus. Because the core mechanisms of complex behaviors such as learning and memory and circadian rhythms appear to be conserved, studies of Fragile X syndrome using Drosophila as a model provide an economy-of-scale for identifying biological processes that likely underlie the abnormal morphology of dendritic spines and behavioral disturbances observed in Fragile X patients.