Odor quality: Discrimination versus free and cued identification

Eighty-two adults, ranging in age from young to elderly, performed odor-quality discrimination and both free and cued identification on six odorants presented at two intensity levels. The odorants simulated the real-world substances banana, licorice, cherry/almond, wintergreen, clove, and lemon. Performance on all three tasks declined with age, but improved with stimulus intensity. Performance at discrimination benefited from the mere availability of the six names during testing. Performance in cued identification far exceeded that in free identification and, for young and middle-aged adults, fell close to that for discrimination. For elderly adults, however, performance in cued identification fell substantially below that in discrimination. Although not entirely free of cognitive influences, discrimination seems to offer particularly clear resolution of alterations in olfactory functioning.     

年龄和性别对气味和词汇的语义识别的不同影响

本研究采用基于人口学特征的大规模取样, 通过线索气味识别测验和词汇测验考察了年龄和性别因素对嗅觉功能和语义知识的影响。1497位健康的成人(35岁~95岁)参与了气味识别和词汇熟练性测验。结果表明年龄对两项测验的成绩都有显著的负面影响, 尽管嗅觉测验的年龄效应更大。女性比男性识别出更多的气味且这种效应与年龄无关, 这进一步证实了先前的观察。本文详细讨论了这些发现的意义。     

Both odor identification and ApoE-ε4 contribute to normative cognitive aging

Research indicates that apoliprotein E (ApoE) plays a role in the development of Alzheimer's disease (AD) and possibly in the cognitive decline associated with normative aging. More recently, researchers have shown that ApoE is expressed in olfactory brain structures, and a relationship among ApoE, AD, and olfactory function has been proposed. In the current analyses, we investigated the contribution of ApoE and odor identification in decline trajectories associated with normative cognitive aging in various domains, using longitudinal data on cognitive performance available from the Swedish Adoption/Twin Study of Aging. Data on both ApoE status and olfactory functioning were available from 455 individuals ranging in age from 50 to 88 years at the first measurement occasion. Odor identification was measured via a mailed survey. Cognitive performance was assessed in up to 5 waves of in-person testing covering a period of 16 years. Latent growth curve analyses incorporating odor identification and ApoE status indicated a main effect of odor identification on the performance level in three cognitive domains: verbal, memory, and speed. A main effect of ApoE on rates of decline after age 65 was found for verbal, spatial, and speed factors. The consistency of results across cognitive domains provides support for theories that posit central nervous system-wide origins of the olfaction-cognition-ApoE relationship; however, olfactory errors and APOE ε4 show unique and differential effects on cognitive trajectory features.     

Influences of item organizability and semantic retrieval cues on word recall in very old age

Abstract

This research investigated the influence of organizational structure in the materials and category cues at retrieval on episodic memory performance in very old age. A community-based sample of healthy, very old adults (N = 224) between 75 and 96 years was presented with two lists of words: a list of semantically unrelated words and a list of words from four taxonomic categories randomly intermixed. Free recall was assessed for both tasks and, for the organizable list, subjects received a cued recall test as well. Results showed an overall age-related deterioration of memory performance, although the ability to utilize item organizability and retrieval cues remained intact across age. Evidence from data on memory performance, as well as analyses of the nature of organizable free recall, suggests that problems at both encoding and retrieval may underlie the age-related performance deficit. In addition, there were age-related increases in (a) forgetting between free and cued recall, and (b) intrusion errors. Finally, regression analyses indicated that, in addition to age, level of schooling as well as markers of general cognitive status (the Mini-Mental State Examination) and fluid intelligence (Block Design) accounted for performance variation across all memory tasks.     

Recognition memory deficits in mild cognitive impairment

ABSTRACT

There is no agreement on the pattern of recognition memory deficits characteristic of patients diagnosed with mild cognitive impairment (MCI). Whereas lower performance in recollection is the hallmark of MCI, there is a strong controversy about possible deficits in familiarity estimates when using recognition memory tasks. The aim of this research is to shed light on the pattern of responding in recollection and familiarity in MCI. Five groups of participants were tested. The main participant samples were those formed by two MCI groups differing in age and an Alzheimer's disease group (AD), which were compared with two control groups. Whereas one of the control groups served to assess the performance of the MCI and AD people, the other one, composed of young healthy participants, served the purpose of evaluating the adequacy of the experimental tasks used in the evaluation of the different components of recognition memory. We used an associative recognition task as a direct index of recollection and a choice task on a pair of stimuli, one of which was perceptually similar to those studied in the associative recognition phase, as an index of familiarity. Our results indicate that recollection decreases with age and neurological status, and familiarity remains stable in the elderly control sample but it is deficient in MCI. This research shows that a unique encoding situation generated deficits in recollective and familiarity mechanisms in mild cognitive impaired individuals, providing evidence for the existence of deficits in both retrieval processes in recognition memory in a MCI stage.     

Identification of odors of edible and nonedible stimuli as affected by age and gender

This study investigated cued odor identification performance with a set of 64 natural common odors (half of edible and half of nonedible stimuli) in three groups of participants: one group of 30 young adults (mean age 25.3 years, range 18-30, SD 3.1) and two groups of older adults-20 young-old (mean age 64.4 years, range 60-69, SD 2.8) and 21 old-old (mean age 74.6 years, range 70-79, SD 2.5). The results showed that 49 of the 64 odors were correctly identified by over 70% of the participants in all groups. The odor identification performance of the young-old adults did not differ from that of the young adults. However, the oldest group showed a significant loss of performance in the task. Women in the young-old group performed better than men, whereas no gender differences were found in the other two age groups. The data obtained in this study will be useful for further perceptual and memory studies conducted in the olfactory modality with young as well as with older participants.     

Paradoxical olfactory function in combat Veterans: The role of PTSD and odor factors

Stress- and trauma-related disorders, including posttraumatic stress disorder (PTSD), are characterized by an increased sensitivity to threat cues. Given that threat detection is a critical function of olfaction and that combat trauma is commonly associated with burning odors, we sought a better understanding of general olfactory function as well as response to specific trauma-related (i.e. burning) odors in combat-related PTSD. Trauma-exposed combat Veterans with (n = 22) and without (n = 25) PTSD were assessed for general and specific odor sensitivities using a variety of tools. Both groups had similar general odor detection thresholds. However, the combat Veterans with PTSD, compared to combat Veterans with comparable trauma exposure but without PTSD, had increased ratings of odor intensity, negative valence, and odor-triggered PTSD symptoms, along with a blunted heart rate in response to burning rubber odor. These findings are discussed within the context of healthy versus pathological changes in olfactory processing that occur over time after psychological trauma.     

Genetic and environmental influences on odor identification ability in the very old

Odor identification ability and cognition were measured in a population-based cohort of 1,222 very old twins and singletons, including 91 centenarians. Heritability for identifying odors was low, in contrast to that for cognition. Common genes were found to contribute to both olfaction and cognition. In a multiple regression model, sex, age, cognitive function, and smoking, but not APOEε4 status, were significant predictors of the olfactory test scores (all ps < 0.001). This study, along with data from other studies, suggests that indices of heritability for odor identification decline with age, likely reflecting adverse environmental influences on the smell system.     

Do pulmonary function and smoking behavior predict cognitive function? findings from a british sample

Abstract

The relationship of smoking behavior, pulmonary function, and four measures of cognitive function was studied in a sample of 4,399 men and women (mean age = 44.7 f 17.1 years; age range: 18 to 94 years) randomly selected from British electoral registers. Each subject was assessed with a face-to-face structured interview (including demographic data, smoking history, and health-related questions) as well as cognitive testing [simple reaction time (SRT), choice reaction time (CRT), incidental memory, and spatial reasoning] and pulmonary function testing. Results indicated that smoking was associated with somewhat better performance on the CRT and memory tasks, and that smoking behavior was not associated with decrements in cognitive performance. Impaired pulmonary function was generally associated with poorer cognitive performance on all of the cognitive measures, suggesting that pulmonary function may be a relevant factor to consider in experimental studies of smoking and cognitive function among healthy adults.     

Stability and consistency of children’s event recall

The purpose of the study was to investigate consistency of recall across different tasks of event recall (similar to eyewitness tasks) and stability of performance across two different events. Additionally, developmental differences in consistency and stability were explored. 6-, 8-, and 10-year-old children were subsequently shown two different events (videos) and were questioned about each event in two separate interviews. For both videos, performance levels in free recall, unbiased cued recall, and suggestibility were at similar levels, with older children generally outperforming younger children. As to intertask consistency of recall, there were significant correlations between correct free recall and correct unbiased cued recall but not between correct free recall and yielding to suggestive questions. All three measures of eyewitness performance showed significant group stability (test-retest correlations) across the two interviews, regardless of age. However, individual stability (lability) was lower, which points to moderate individual differences in stability across the two interviews. The findings are discussed in terms of underlying cognitive skills and the problem of predicting a single child’s memory performance in real cases of eyewitness testimony.     

Individual differences in self-initiated processing at encoding and retrieval: A latent variable analysis

The current study examined individual differences in self-initiated processing (SIP) in memory tasks. Participants performed four memory tasks that varied the amount of SIP required at encoding, retrieval, or both as well as cognitive ability measures. It was found that the correlation between recall performance and cognitive abilities changed as a function of the amount of SIP required. Additionally, it was found that although both free and cued recall measures accounted for variance in cognitive abilities, only the free recall accounted for unique variance in cognitive abilities. It is suggested that the predictive power of a task is determined in part based on the amount of SIP required.     

Individual differences in self-initiated processing at encoding and retrieval: a latent variable analysis

The current study examined individual differences in self-initiated processing (SIP) in memory tasks. Participants performed four memory tasks that varied the amount of SIP required at encoding, retrieval, or both as well as cognitive ability measures. It was found that the correlation between recall performance and cognitive abilities changed as a function of the amount of SIP required. Additionally, it was found that although both free and cued recall measures accounted for variance in cognitive abilities, only the free recall accounted for unique variance in cognitive abilities. It is suggested that the predictive power of a task is determined in part based on the amount of SIP required.     

Verified Hormone Therapy Improves Episodic Memory Performance in Healthy Postmenopausal Women

ABSTRACT

Studies of hormone therapy (HT) and cognition have yielded conflicting results. The aim of this observational study was to examine the effect of estradiol, via serum verified HT (estradiol, estriol, progesterone) and endogenous estradiol, on 108 healthy postmenopausal women's cognitive performance. The results demonstrated that the 43 HT-users performed at a significantly higher level than non-users on episodic memory tasks and on a verbal fluency task, whereas HT-users and non-users did not differ on tasks assessing semantic memory and spatial visualization. In addition, there was a positive relationship between serum estradiol level and episodic memory performance, indicating that postmenopausal HT is associated with enhanced episodic memory and verbal fluency, independent of age and education. These observational results suggest that HT use may be sufficient to exert small, yet positive effects on female sensitive cognitive tasks. Hormone therapy compliance and formulation is discussed as confounding factors in previous research.     

Parental educational level influence on memory and executive performance in children

IntroductionThe influence of Parental Educational Status (PES) on cognitive performance has been confirmed in several studies.ObjectiveThe aim of this study was to explore the relationship between PES and several domains of cognitive functioning and examine, through mediation analyses, the relationship between PES, language, and cognitive tasks.MethodWe first administered tasks measuring memory, executive and attentional abilities to 64 European native French speakers, divided into two groups of children according to parents’ educational status.ResultsThe results suggest that, on most tasks, the effect of socio-educational status is mediated by language abilities. However, because the results were less clear for executive functions, we carried out a second experiment in which we administered more specific executive measures (i.e. inhibition, cognitive flexibility, updating and reasoning) to 80 children.ConclusionThe results confirmed the influence of the parents’ educational status on the executive functioning and also that, contrary to other cognitive functions, this influence on executive tasks is not completely explained by language differences.     

Implicit and explicit memory in young and older adults

In three experiments, young and older adults were compared on both implicit and explicit memory tasks. The size of repetition priming effects in word completion and in perceptual identification tasks did not differ reliably across ages. However, age-related decrements in performance were obtained in free recall, cued recall, and recognition. These results, similar to those observed in amnesics, suggest that older adults are impaired on tasks which require conscious recollection but that memory which depends on automatic activation processes in relatively unaffected by age.     

Nonword repetition and identification skills in Kannada speaking school-aged children who do and do not stutter

PurposeThe present study employed nonword repetition and nonword identification tasks to explore the phonological working memory (PWM) abilities and its interaction with speech motor control in school-aged children who do and do not stutter.MethodParticipants were 17 children who stutter (CWS) (Age range = 7–12) and 17 age and gender-matched children who do not stutter (CWNS). For the nonword repetition task, the participants repeated sets of 2-, 3-, and 4-syllable nonwords (n = 12 per set). The participants silently identified a target nonword from a subsequent set of three nonwords (n = 12 per 2-, 3- and 4-syllable length) for the nonword identification task. The performance of CWS on the nonword repetition task was compared with the CWNS for the mean number of accurate repetitions, number of trials taken, number of accurate repetitions on initial trial, and number of fluent repetitions across the three-syllable conditions for the tasks. For the nonword identification task, the number of nonwords identified accurately by the two groups were subjected to analysis.ResultsCWS were significantly less accurate on the initial production of nonwords and required significantly more number of attempts to repeat the nonword accurately. Further for the nonword identification task, CWS were significantly less accurate than CWNS in correctly identifying the target nonword.ConclusionsThe present findings suggest that, in addition to limitations in PWM capacity, an unstable speech motor control system in CWS may lead to dysfluent speech.     

Math and Memory in Bilingual Preschoolers: The Relations Between Bilingualism,Working Memory,and Numerical Knowledge

ABSTRACT

Bilingual children exhibit enhanced working memory (WM) skill relative to monolingual children, which could have implications for early mathematics development. Competency in mathematics is supported by conceptual and procedural mathematical knowledge, and numerical knowledge is in turn supported by underlying cognitive processes such as WM. Building on this evidence, we investigated whether bilingual preschoolers demonstrated, relative to monolingual peers, enhanced performance on WM and greater numerical knowledge. We examined the role of WM in numerical understanding for both monolingual and bilingual children. Participants were 4- and 5-year old children (74) recruited from preschools serving families from a range of socioeconomic, racial, and ethnic backgrounds. Participants completed a nonverbal WM task and a range of numerical-knowledge measures, specifically numeral identification, addition, symbolic magnitude comparison, and nonsymbolic magnitude comparison tasks. Results revealed that bilingual children outperformed monolingual peers on WM even after controlling for age and socioeconomic status (SES). Bilingual children also demonstrated greater performance on addition and numeral identification tasks. For all tasks except numeral identification, WM predicted children’s performance on numerical knowledge measures. We discuss results in terms of the possible unique cognitive and academic advantages bilingual children may have.     

Differences in familiarity according to the cognitive reserve of healthy elderly people / Diferencias en familiaridad en función de la reserva cognitiva en ancianos sanos

Abstract

This study examines the relationship between cognitive reserve and familiarity processes in recognition memory. We hypothesize that people with high cognitive reserve are able to better compensate in alternative information retrieval processes. Forty-five participants, divided into high and low cognitive reserve groups, conducted a recognition experiment where they were asked to discriminate between studied and non-studied words that varied in perceptual familiarity. The results indicated that participants were able to use perceptual familiarity to improve their level of recognition. More importantly, people with high cognitive reserve used familiarity better than those with low cognitive reserve. The results provide the first empirical evidence indicating that people with high cognitive reserve are more efficient at balancing recollection and familiarity processes, and thus maintain a better performance level than those with low cognitive reserve.     

Are older adults less efficient in making attributions about the origin of memories for web interaction?

IntroductionAs people age, they may be less likely to recollect where or when an event took place. However, few studies of source monitoring and aging have used tasks that are similar to what people do in everyday life.ObjectivePotential age-related differences in making attributions about the origin of remembered events in Web interaction are examined in the present study.MethodsA Web-based source-monitoring paradigm was modelled to assess both item and source memory, which incorporated typical Web search tasks.ResultsOlder adults exhibited a reduced ability in navigation-oriented search, where both a measure of processing speed and a measure of executive function were significant predictors of performance. They were less able to recognize and recollect items previously encountered in web pages. However, source memory was not more impaired with age than item memory. Interestingly, although the addition of cognitive operations as a cue to source had no impact on source memory, it resulted in increased recognition and recollection in the older adults.ConclusionMore generally, recognition and recollection appeared to be dissociated from source memory as a function of different individual difference measures.     

Recognition memory deficits in mild cognitive impairment

ABSTRACT There is no agreement on the pattern of recognition memory deficits characteristic of patients diagnosed with mild cognitive impairment (MCI). Whereas lower performance in recollection is the hallmark of MCI, there is a strong controversy about possible deficits in familiarity estimates when using recognition memory tasks. The aim of this research is to shed light on the pattern of responding in recollection and familiarity in MCI. Five groups of participants were tested. The main participant samples were those formed by two MCI groups differing in age and an Alzheimer's disease group (AD), which were compared with two control groups. Whereas one of the control groups served to assess the performance of the MCI and AD people, the other one, composed of young healthy participants, served the purpose of evaluating the adequacy of the experimental tasks used in the evaluation of the different components of recognition memory. We used an associative recognition task as a direct index of recollection and a choice task on a pair of stimuli, one of which was perceptually similar to those studied in the associative recognition phase, as an index of familiarity. Our results indicate that recollection decreases with age and neurological status, and familiarity remains stable in the elderly control sample but it is deficient in MCI. This research shows that a unique encoding situation generated deficits in recollective and familiarity mechanisms in mild cognitive impaired individuals, providing evidence for the existence of deficits in both retrieval processes in recognition memory in a MCI stage.