Musical instrument naming impairments: the crucial exception to the living/nonliving dichotomy in category-specific agnosia

In category-specific agnosia (CSA) patients typically have more trouble naming animals, fruits, and vegetables than tools, furniture, and articles of clothing. A crucial exception to this living vs nonliving rule involves the category of musical instruments. Patients with problems naming living objects often repeatedly fail to name musical instruments. In CSA it is crucial to equate living and nonliving object lists on object name frequency, complexity, and familiarity. The present study shows, however, that even the most rigorously controlled object lists can lead to erroneous conclusions if nonliving stimuli contain an overrepresentation of musical instruments. Naming capabilities of a herpes encephalitis patient were assessed using matched lists of living and nonliving objects and showed no indication of category-specific deficits. When exemplars were separated into biological objects, musical instruments and man-made artifacts, strong category-specificity emerged: artifact naming was flawless whereas musical instrument and biological object naming were both severely impaired. It is concluded that CSA is a veridical phenomenon but that our understanding of CSA is limited by adhering to the spurious living/nonliving distinction.     

The visual basis of category effects in object identification: evidence from the visual hemifield paradigm

The basis for the category specific living things advantage in object recognition (i.e., faster and more accurate identification of living compared to nonliving things) was investigated in two experiments. It was hypothesised that the global shape of living things on average provides more information about their basic level identity than the global shape of nonliving things. In two experiments subjects performed name-picture or picture-name verification tasks, in which blurred or clear images of living and nonliving things were presented in either the right or the left visual hemifield. With blurred images, recognition performance was worst for nonliving things presented to the right visual field/left hemisphere, indicating that the lack of visual detail in the stimulus combined with a left hemisphere bias toward processing high frequency visual elements proved detrimental for processing nonliving stimuli in this condition. In addition, an overall living things advantage was observed in both experiments. This advantage was considerably larger with blurred images than with clear. These results are compatible with the global shape hypothesis and converge with evidence using other paradigms.     

Outline shape is a mediator of object recognition that is particularly important for living things

We assess the importance of outline shape in mediating the recognition of living and nonliving things. Natural objects were presented as shaded line drawings or silhouettes, and were living and nonliving things. For object decision (deciding whether an object may be encountered in real life) there were longer response times to nonliving than to living things. Importantly, this category difference was greater for silhouettes than for shaded line drawings. For naming, similar category and stimulus differences were evident, but were not as pronounced. We also examined effects of prior naming on subsequent object decision performance. Repetition priming was equivalent for nonliving and living things. However, prior presentation of silhouettes (but not shaded line drawings) reduced the longer RT to nonliving things relative to living things in silhouette object decision. We propose that outline contour benefits recognition of living things more than nonliving things: For nonliving things, there may be greater 2-D/3-D interpretational ambiguity, and/or they may possess fewer salient features.     

Evaluating feature-category relations using semantic fluency tasks

The issue of the relationship between semantic features and semantic categories has been raised by Warrington and colleagues, who claimed that sensory and functional-associative features are differentially important in determining the meaning of living and nonliving things (Warrington & McCarthy, 1983, 1987; Warrington & Shallice, 1984). In the present study, the effectiveness of semantic memory search for living and nonliving things with sensory and functional-associative search cues was evaluated through eight different adaptations of the semantic fluency task. More living thing responses and clusters were generated from sensory than from functional-associative search cues, while the reverse pattern holds for nonliving things responses and clusters. The results thus provide consistent empirical support for the assumption that sensory properties are fundamental in the representation of living things, while functional-associative properties are fundamental in the semantic representation of nonliving things.     

Names,concepts, features and the living/nonliving things dissociation

The present paper evaluates different hypotheses for explaining the living/nonliving things dissociation phenomenon in terms of feature type, considering the role of this dimension in the organization of conceptual semantic representations and in the activation of name representations. For this purpose we used Sloman and associates' (Memory and Cognition 27(3) (1999) 526; Cognitive Science 22(2) (1998) 189) name centrality and conceptual centrality tasks and asked subjects to judge functional and perceptual/visual features of living and nonliving items. Conceptual centrality results are more in accordance with a "single feature-domain connection hypothesis" where visual features are more important than functional features for the representation of living things and no feature type advantage is found for nonliving things. Name centrality results show that functional features are more important than sensory/visual features overall, a result that is not predicted by any of the hypotheses considered. The fact that the two judgments diverge emphasizes their importance for evaluating the role of feature type in the living/nonliving dissociation. Implications for explaining this phenomenon are also discussed.     

Semantic processing of living and nonliving concepts across the cerebral hemispheres

Studies of patients with category-specific semantic deficits suggest that the right and left cerebral hemispheres may be differently involved in the processing of living and nonliving domains concepts. In this study, we investigate whether there are hemisphere differences in the semantic processing of these domains in healthy volunteers. Based on the neuropsychological findings, we predicted a disadvantage for nonliving compared to living concepts in the right hemisphere. Our prediction was supported, in that semantic decisions to nonliving concepts were significantly slower and more error-prone when presented to the right hemisphere. In contrast there were no hemisphere differences for living concepts. These findings are consistent with either differential representation or processing of concepts across right and left hemispheres. However, we also found a disadvantage for nonliving things compared to living things in the left hemisphere, which is not consistent with a simple representation account. We discuss these findings in terms of qualitatively different semantic processing in right and left hemispheres within the framework of a distributed model of conceptual representation.     

Category-specific naming errors in normal subjects: the influence of evolution and experience

The importance of "artifactual" variables (such as conceptual familiarity) have been highlighted in current accounts of category-specific disorders for living things (e.g., Funnell & Sheridan, 1992). The difficulties experienced by patients are essentially viewed as an exaggeration of normal processes and the implication is that normal subjects should also have greater difficulty naming living items (because they have lower conceptual familiarity than nonliving things). The current study examined normal subjects' ability to name pictures of artifact-matched sets of living and nonliving things in a naming-to-deadline paradigm. Contrary to the prediction, normal subjects made more nonliving naming errors. Furthermore, female subjects made more nonliving-thing errors than male subjects. These findings could not be reduced to differences in either category-based or gender-based familiarity ratings. Rather, it is proposed that an elaborated domain-specific evolutionary model parsimoniously explains both the greater incidence of living thing deficits in patients and the better performance of normal subjects with living things.     

Left anterior lobectomy and category-specific naming

Damasio and colleagues (1996) have proposed that the left anterior temporal region supports knowledge pertaining to living objects, whereas more posterior temporal regions play a critical role in naming nonliving things. Accordingly, one might expect that left-sided anterior temporal lobectomy should have a more profound effect on the naming of living as opposed to nonliving things. As part of a multicenter collaborative project, seventy-nine patients (all left-hemisphere speech dominant) were tested pre- and post-left-temporal lobectomy on a task that required naming of living and nonliving items equated for name frequency, familiarity, and visual complexity. Consistent with the proposals of Damasio et al. (1996), left temporal lobectomy impaired naming ability, particularly for living things. When individual outcomes were considered, twice as many patients showed a relative decline in naming living as opposed to nonliving things.     

The effect of age of acquisition in visual word processing: further evidence for the semantic hypothesis

The authors investigated whether the meaning of visually presented words is activated faster for early-acquired words than for late-acquired words. They addressed the issue using the semantic Simon paradigm. In this paradigm, participants are instructed to decide whether a stimulus word is printed in uppercase or lowercase letters. However, they have to respond with a verbal label ("living" or "nonliving") that is either congruent with the meaning of the word (e.g., saying "living" to the stimulus DOG) or incongruent (e.g., saying "nonliving" to the stimulus dog). Results showed a significant congruency effect that was stronger for early-acquired words than for late-acquired words. The authors conclude that the age of acquisition is an important variable in the activation of the meaning of visually presented words.     

An attenuation of the 'normal' category effect in patients with Alzheimer's disease: a review and bootstrap analysis

There is a consensus that Alzheimer's disease (AD) impairs semantic information, with one of the first markers being anomia i.e. an impaired ability to name items. Doubts remain, however, about whether this naming impairment differentially affects items from the living and nonliving knowledge domains. Most studies have reported an impairment for naming living things (e.g. animals or plants), a minority have found an impairment for nonliving things (e.g. tools or vehicles), and some have found no category-specific effect. A survey of the literature reveals that this lack of agreement may reflect a failure to control for intrinsic variables (such as familiarity) and the problems associated with ceiling effects in the control data. Investigating picture naming in 32 AD patients and 34 elderly controls, we used bootstrap techniques to deal with the abnormal distributions in both groups. Our analyses revealed the previously reported impairment for naming living things in AD patients and that this persisted even when intrinsic variables were covaried; however, covarying control performance eliminated the significant category effect. Indeed, the within-group comparison of living and nonliving naming revealed a larger effect size for controls than patients. We conclude that the category effect in Alzheimer's disease is no larger than is expected in the healthy brain and may even represent a small diminution of the normal profile.     

Hearing living symbols and nonliving icons: Category specificities in the cognitive processing of environmental sounds

The neurocognitive processing of environmental sounds and linguistic stimuli shares common semantic resources and can lead to the activation of motor programs for the generation of the passively heard sound or speech. We investigated the extent to which the cognition of environmental sounds, like that of language, relies on symbolic mental representations independent of the acoustic input. In a hierarchical sorting task, we found that evaluation of nonliving sounds is consistently biased toward a focus on acoustical information. However, the evaluation of living sounds focuses spontaneously on sound-independent semantic information, but can rely on acoustical information after exposure to a context consisting of nonliving sounds. We interpret these results as support for a robust iconic processing strategy for nonliving sounds and a flexible symbolic processing strategy for living sounds.     

Implicit access to semantic information

Three experiments investigating the patient M.S.'s semantic memory are reported. Experiments 1 and 2 involved a category-membership decision task, in which M.S. was asked to determine whether a noun was a member of a specified semantic category. His performance in Experiment 1 was impaired for nouns from living categories in comparison with nouns from nonliving categories, and this impairment was especially marked for nouns of low typicality. Experiment 2 demonstrated an equivalent pattern of very poor performance to nouns of low familiarity from living categories. In Experiment 3 the effect of a category label on lexical decision was examined, using category labels as primes preceding nouns or pronounceable nonwords. Facilitation from related category label primes was found for typical and untypical members of living and nonliving semantic categories. These findings demonstrate that M.S. has impaired knowledge of the structure of living semantic categories when explicit access to this information is required (Experiments 1 and 2), but that some form of preserved category structure can be demonstrated in tasks which assess this implicitly (Experiment 3).     

The influence of surface and edge-based visual similarity on object recognition

The role of 'visual similarity' has been emphasised in object recognition and in particular, for category-specific agnosias. [Laws and Gale, 2002] recently described a measure of pixel-level visual overlap for line drawings (Euclidean Overlap: EO[line]) that distinguished living and nonliving things and predicted normal naming errors and latencies ( [Laws et al., 2002]). Nevertheless, it is important to extend such analyses to stimuli other than line drawings. We therefore developed the same measure for greyscale versions of the same stimuli (EO[grey]), i.e., that contain shading and texture information. EO[grey], however, failed to differentiate living from nonliving things and failed to correlate with naming latencies to the greyscale images. By contrast, EO[line] did correlate with the naming latencies. This suggests that similarity of edge information is more influential than similarity of surface characteristics for naming and for categorically separating living and nonliving things (be they line drawings or greyscale images).     

Why are rocks pointy? Children's preference for teleological explanations of the natural world

Teleological explanations are based on the assumption that an object or behavior exists for a purpose. Two studies explored the tendency of adults and first-, second-, and fourth-grade elementary-school children to explain the properties of living and nonliving natural kinds in teleological terms. Consistent with the hypothesis that young children possess a promiscuous teleological tendency, Study 1 found that children were more likely than adults to broadly explain the properties of both living and nonliving natural kinds in teleological terms, although the kinds of functions that they endorsed varied with age. Study 2 was an attempt to reduce children's broad teleological bias by introducing a pretrial that described, in nonteleological terms, the physical process by which nonliving natural kinds form. In spite of this attempt, Study 2 replicated the effects of Study 1, with only fourth graders showing any shift in preference for teleological explanation.     

Crowded and sparse domains in object recognition: consequences for categorization and naming

Some models of object recognition propose that items from structurally crowded categories (e.g., living things) permit faster access to superordinate semantic information than structurally dissimilar categories (e.g., nonliving things), but slower access to individual object information when naming items. We present four experiments that utilize the same matched stimuli: two examine superordinate categorization and two examine picture naming. Experiments 1 and 2 required participants to sort pictures into their appropriate superordinate categories and both revealed faster categorization for living than nonliving things. Nonetheless, the living thing superiority disappeared when the atypical categories of body parts and musical instruments were excluded. Experiment 3 examined naming latency and found no difference between living and nonliving things. This finding was replicated in Experiment 4 where the same items were presented in different formats (e.g., color and line-drawn versions). Taken as a whole, these experiments show that the ease with which people categorize items maps strongly onto the ease with which they name them.     

Analyzing the factors underlying the structure and computation of the meaning of chipmunk,cherry, chisel,cheese, and cello (and many other such concrete nouns)

Seven trends regarding the categories that tend to be impaired/preserved in category-specific semantic deficits were identified. The authors hypothesized that these trends arise despite the multiple sources of variation in patient testing because numerous factors that structure semantic memory probabilistically converge to make some categories of knowledge more susceptible to damage than others. Analysis of semantic feature norms and corpus data for 541 concepts revealed that differences in the distribution of knowledge types across categories are sufficient to explain 6 of the trends and are necessary to explain loss of knowledge about nonliving things. Feature informativeness, concept confusability, visual complexity, familiarity, and name frequency contributed to this patterning and provide insight into why knowledge about living things is most often impaired.     

A functional account of degrees of minimal chemical life

This paper describes and defends the view that minimal chemical life essentially involves the chemical integration of three chemical functionalities: containment, metabolism, and program (Rasmussen et al. in Protocells: bridging nonliving and living matter, 2009a). This view is illustrated and explained with the help of CMP and Rasmussen diagrams (Rasmussen et al. In: Rasmussen et al. (eds.) in Protocells: bridging nonliving and living matter, 71–100, 2009b), both of which represent the key chemical functional dependencies among containment, metabolism, and program. The CMP model of minimal chemical life gains some support from the broad view of life as open-ended evolution, which I have defended elsewhere (Bedau in The philosophy of artificial life, 1996; Bedau in Artificial Life, 4:125–140, 1998). Further support comes from the natural way the CMP model resolves the puzzle about whether life is a matter of degree.     

Developmental "Roots" in Mature Biological Knowledge

ABSTRACT— Young children tend to claim that moving artifacts and nonliving natural kinds are alive, but neglect to ascribe life to plants. This research tested whether adults exhibit similar confusions when verifying life status in a speeded classification task. Experiment 1 showed that undergraduates encounter greater difficulty (reduced accuracy and increased response times) in determining life status for plants, relative to animals, and for natural and moving nonliving things, relative to artifacts and nonmoving things. Experiment 2 replicated these effects in university biology professors. The professors showed a significantly reduced effect size for living things, as compared with the students, but still showed greater difficulty for plants than animals, even as no differences from the students were apparent in their responses to nonliving things. These results suggest that mature biological knowledge relies on a developmental foundation that is not radically overwritten or erased with the profound conceptual changes that accompany mastery of the domain.     

A computational model of semantic memory impairment: modality specificity and emergent category specificity.

It is demonstrated how a modality-specific semantic memory system can account for category-specific impairments after brain damage. In Experiment 1, the hypothesis that visual and functional knowledge play different roles in the representation of living things and nonliving things is tested and confirmed. A parallel distributed processing model of semantic memory in which knowledge is subdivided by modality into visual and functional components is described. In Experiment 2, the model is lesioned, and it is confirmed that damage to visual semantics primarily impairs knowledge of living things, and damage to functional semantics primarily impairs knowledge of nonliving things. In Experiment 3, it is demonstrated that the model accounts naturally for a finding that had appeared problematic for a modality-specific architecture, namely, impaired retrieval of functional knowledge about living things. Finally, in Experiment 4, it is shown how the model can account for a recent observation of impaired knowledge of living things only when knowledge is probed verbally.