Tactile perceptual processes and their relationship to somatoform disorders

The Somatic Signal Detection Task (SSDT) is a recent paradigm serving to examine perceptual processes likely relevant for somatoform disorders. We tested whether touch illusions are more easily induced in individuals suffering from somatoform disorders (SFD) and whether their perceptual threshold for tactile stimuli is lower compared to healthy controls. Thirty-three participants with SFD and 32 healthy controls reported whether they recognized near-threshold tactile stimuli at their fingertip, which were presented in half of the test trials. With a probability of 0.5, an auxiliary visual stimulus was additionally presented. Tactile detection thresholds, tactile sensitivity, response bias, and the rate of false-positive perceptions of the tactile stimulus were assessed. In both groups, the light stimulus led to an amelioration of tactile sensitivity as well as to a more liberal response style. The SFD group was characterized by a more liberal response bias in the first half of the light-absent condition compared to the healthy controls. Within the SFD group, the report of somatoform (especially pseudoneurological) symptoms correlated positively with illusory tactile perceptions in the SSDT. Tactile thresholds in the SSDT were measured reliably (rtt = .86) and were significantly lower in the SFD group. The notion that general perceptual dispositions influence the formation of symptom perception may thus complement cognitive models of SFD.     

Psychophysiologic abnormalities in schizophrenia: some implications for therapy

On the basis of several studies, some psychophysiological activation abnormalities in schizophrenia are explained. These abnormalities give rise to at least three therapeutic aims: (1) As some psychophysiological systems may be under- and others overaroused in schizophrenic patients compared to normal controls, therapeutic interventions should approach the systems selectively. (2) The ability to modulate the psychophysiological activation, which is diminished in schizophrenic patients, should be improved. (3) Schizophrenic patients need a more differentiated perception of their own state of activation. These aims contrast somewhat with past therapeutic studies, which tried to change activation for the purpose of tension reduction. It seems advisable to link basic psychophysiological research more closely to the development of therapies.     

Is interoceptive awareness really altered in somatoform disorders? Testing competing theories with two paradigms of heartbeat perception

Alterations in the perception of body signals (i.e., interoceptive awareness [IA]) are considered crucial for the development and maintenance of somatoform disorders (SFDs). However, competing theories come to different conclusions about whether IA is increased or decreased in SFDs. The present study investigated IA in 23 patients with SFDs (as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) and in 27 healthy controls. IA was reliably assessed with two well-established heartbeat perception paradigms (heartbeat discrimination task and mental tracking task). The results of both paradigms showed no evidence for increased IA in patients with SFDs. Correlational analyses revealed that having a higher number of somatoform symptoms was significantly linked to lower (rather than higher) IA in SFDs. These findings are in line with recent cognitive approaches to SFDs that stress the importance of biased schema-guided processing of interoceptive information. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Somatization tendencies and ability to detect internal body cues

39 subjects performed a task in which they were required to detect the presence of a resistive load during the inhalation phase of breathing. Subjects were also measured on somatization tendencies, using the SCL-90-R test. A signal-detection analysis indicated an inverse relationship between ability to detect the resistive load during breathing and somatization score. Results are discussed relative to possible ramifications for somatoform disorders.     

Hypochondriasis Among Patients with Multiple Somatoform Symptoms—Psychopathology and Outcome of a Cognitive-Behavioral Therapy

As hypochondriasis often occurs with somatization, patients with somatization disorder plus hypochondriasis were compared to patients with somatization syndrome alone regarding psychopathology, patterns of physical symptoms and outcome of a cognitive-behavioral inpatient treatment. A sample of patients with DSM-IV hypochondriasis and multiple somatoform symptoms(N = 27) and a matched sample of patients with multiple somatoform symptoms but without hypochondriasis (N = 27) were assessed. All subjects obtained a cognitive-behavioral treatment for somatization and hypochondriasis. Assessment took place at admission and at one-year follow-up. Only a few differences between the groups were found: Hypochondriacs suffered more often from abdominal pain, and they reported a higher intolerance of bodily complaints. At follow-up, all outcome variables improved significantly. High effect sizes were found for the reduction of symptoms and the mean number of visits to the doctor. The specific effect on health care use highlights the socioeconomic relevance of these results.     

A new procedure for assessment of proprioception.

A new method for the assessment of proprioception was developed and tested with 40 healthy subjects on two facial muscles (i.e., masseter and zygomatic muscles). The experiment was repeated after 3 1/2 months. In our study, proprioception was studied with respect to sensations arising from the muscle spindles and tendon organs. Therefore, myesthesia was investigated, which was assessed by the correspondence between a voluntary muscle contraction and its immediate replication. Good perception was defined by a small integral of differences, standardized by duration and intensity of the contraction, and its replication. Results show that this measure is independent of the characteristics of muscle activation. In concordance with our hypothesis, myesthesia was superior in a muscle richly supplied with muscle spindles and afferent fibers (i.e., masseter muscle), to that for a muscle less prepared for afferent information processing (i.e., zygomatus major).     

Cognitive-affective neuroscience of somatization disorder and functional somatic syndromes: reconceptualizing the triad of depression-anxiety-somatic symptoms

Somatization disorder is a somatoform disorder that overlaps with a number of functional somatic syndromes and has high comorbidity with major depression and anxiety disorders. Proposals have been made for revising the category of somatoform disorders, for simplifying the criteria for somatization disorder, and for emphasizing the unitary nature of the functional somatic syndromes in future classifications. A review of the cognitive-affective neuroscience of somatization disorder and related conditions suggests that overlapping psychobiological mechanisms mediate depression, anxiety, and somatization symptoms. Particular genes and environments may contribute to determining whether symptoms are predominantly depressive, anxious, or somatic, and there are perhaps also overlaps and distinctions in the distal evolutionary mechanisms that produce these symptoms.     

Somatoforme Störungen und Bindungstheorie

Somatoform disorders are not only marked by somatic symptoms, but also by significant disturbances in interpersonal relationships. Interpersonal difficulties – including the maladaptive pattern of illness behavior and the resulting difficult doctor-patient-relationship – are an important field of therapeutic intervention (Nickel u. Egle 1999). The interpersonal problems which are characteristic in patients with somatoform disorders draw attention to the developmental aspects of these conditions. Attachment theory provides a promising framework for understanding these developmental features. In the paper presented we therefore apply concepts and observations from attachment theory to somatoform disorders. After a brief review of attachment theory we specifically discuss the developmental aspects of representation formation in somatization. As next, empirical evidence is reviewed that link attachment insecurity to the development of somatoform disorders. Finally a vulnerability model of somatoform disorders is outlined.     

Aus vier mach zwei

Background

The diagnostic and statistical manual of mental disorders 5 (DSM-5) includes a revision of the DSM-IV criteria for somatoform disorders. The aim of the current work was to investigate whether (a) patients with DSM-IV diagnoses of somatization disorder, pain disorder and hypochondriasis and (b) whether patients categorized as having the DSM-5 somatic symptom disorder and illness anxiety disorder differ with respect to illness anxiety and cognition regarding somatic symptoms.

Material and methods

The data from 269 inpatients from the psychosomatic clinic Schön Klinik Bad Bramstedt were used. Somatoform disorders were diagnosed using the German version of the structured clinical interview for DSM-IV (SCID).

Results

Patients with a DSM-IV diagnosis of hypochondriasis differed in illness anxiety and catastrophizing interpretation of somatic symptoms compared to patients with other somatoform disorders. Patients with illness anxiety disorder differed in the catastrophizing interpretation of physical symptoms, autonomic sensations, bodily weakness and intolerance of physical complaints compared to patients with somatic symptom disorder.

Conclusion

The present results indicate that illness anxiety and a catastrophizing interpretation of somatic symptoms play a fundamental role in patients with somatoform disorders. Therefore, psychotherapy should address illness anxiety and health-related concerns in all patients with somatoform disorders.     

Poor hand-pointing to sounds in right brain-damaged patients: Not just a problem of spatial-hearing

We asked 22 right brain-damaged (RBD) patients and 11 elderly healthy controls to perform hand-pointing movements to free-field unseen sounds, while modulating two non-auditory variables: the initial position of the responding hand (left, centre or right) and the presence or absence of task-irrelevant ambient vision. RBD patients suffering from visual neglect, unlike RBD patients without neglect and healthy controls, showed a systematic rightward error in sound localisation, which was modulated by the non-auditory variables. Localisation errors were exacerbated by initial hand-position to the right of the body-midline, and reduced by the leftwards initial hand-position. Moreover, for the visual neglect patients, mere presence of ambient vision worsened localisation errors. These results demonstrate that although hand-pointing to sounds has often been considered a straightforward approach to investigate sound-localisation abilities in brain-damaged patients, in some patients it may actually reveal localisation deficits that reflect a combination of impaired spatial-hearing and spatial biases from other sensory modalities (i.e., vision and proprioception).     

Affektverarbeitung und Beziehungsgestaltung bei somatoformen Störungen

Somatoform disorders are usually associated with disturbances in affective processing and consequently with relational disorders. The effect of psychotherapy on the emotional regulation and the relational behaviour in the course of treatment of a patient with somatoform autonomous dysfunction and dysthymia has been examined. Pre-post comparisons of inpatient treatment have been performed by means of standardized questionnaire data; the course of therapy has been evaluated by the analysis of the dependence of the leading symptom of hypogastric pain on mood parameters with the help of multivariate time-series analyses. One effect of psychotherapy was the initiation of an intrapsychic discourse, which led to an improved ability of affect regulation as well as to a better functioning in relationships. This was accompanied by a reduction of somatization. The interrelations between somatization, affect- and relationship-regulation are discussed.     

Perceptual distortion of intrapersonal and near-personal space sensed by proprioception

It is known that the illusory displacement of a vibrated limb can be transferred to a nonvibrated contacted limb. The purpose of this study was to quantify and compare the transferred illusory displacements occurring in the intrapersonal and near-personal space. In two tasks, 8 male and 8 female blindfolded subjects estimated (1) the height of the left elbow and (2) the height of an external object located at the same height as the left elbow, by the proprioception of the right arm which was Subject to illusory displacement. If the internal representation of the left elbow in one's body schema could provide precise information of its static position independently of the proprioception of the right arm, the perceived displacement of the right arm might be smaller when influenced by proprioceptive information from the static left arm, than when in contrast instead with an object which is not a body part. There was no difference in the estimation of illusory displacement between male and female subjects and between right and left arms. No significant difference was observed between transferred displacements of the left elbow and the object. This means that the perception of limb position sensed by the proprioception of another limb can be distorted as easily as the perception of location of an external object. This suggests that the internal representation of static limb position is not enough to provide the correct information of current limb position in the absence of vision.     

Somatic symptom reporting has a dimensional latent structure: Results from taxometric analyses

Medically unexplained symptoms (MUS) are one of the key features of somatoform disorders. Although MUS are currently treated as both categorical (in terms of the diagnosis of somatoform disorders) and dimensional (in terms of quantitative measures of somatization/somatic symptom reporting), little is known about the empirical latent structure of MUS. Using taxometric analyses, the latent structure of somatic symptom reporting was analyzed with the Patient Health Questionnaire (PHQ)-15 in two student samples (N = 782 and N = 2,577) and a primary care sample (N = 519). We applied three popular taxometric methods: Maximum Eigenvalue (MAXEIG), Mean Above Minus Below a Cut (MAMBAC) and Latent-Mode (L-Mode). Simulation data were created to evaluate the appropriateness of the data for our analyses and to create the comparison curve fit index (CCFI) as an objective outcome measure. The results of all taxometric methods in any of the three data sets were in favor of a dimensional solution (CCFI < .50). Simulated taxonic and dimensional datasets differed substantially and the samples were appropriate for taxometric analysis. Accordingly, the latent structure of somatization/somatic symptom reporting as assessed by the PHQ-15 is dimensional in both primary care and student samples. Implications regarding the practical application as well as models of etiology and pathogenesis of somatic symptom reporting are discussed. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Actual neurosis as the underlying psychic structure of panic disorder, somatization, and somatoform disorder: an integration of Freudian and attachment perspectives

Starting from a contemporary critique of the DSM-IV, this paper argues that the diagnostic categories of panic disorder somatization, and undifferentiated somatoform disorders can be understood as belonging to a common type of psychopathology--i.e., the Freudian actual neuroses. In addition to their strong clinical similarity, these disorders share an etiological similarity; and the authors propose a combination of Freud's focus on this type of patient's inability to represent an endogenous drive arousal with the post-Freudian focus on separation anxiety. An etiological hypothesis is put forward based on contemporary psychoanalytic attachment theory, highlighting mentalization. Concrete implications for a psychoanalytically based treatment are proposed.     

Psychological Disturbances in Patients With Sphincter of Oddi Dysfunction

Sphincter of Oddi dysfunction (SOD) is a functional gastrointestinal disorder (FGID), which causes pancreatobiliary-type pain, cholestasis, and/or pancreatitis. Only a few studies have assessed the level of psychological distress in this population compared to healthy subjects or patients with other gastrointestinal disorders. In this study, we examined the self-reported level of psychological distress and certain psychiatric symptoms of SOD patients, and we compared them to depressed patients as well as healthy subjects. The results indicate that SOD patients have significantly lower levels of global and specific symptoms compared to depressed patients. When compared to healthy subjects, SOD patients expressed significantly higher levels of irritability–oversensitivity, and there was a trend toward higher levels of somatization.     

A threat-detection advantage in those with autism spectrum disorders

Identifying threatening expressions is a significant social perceptual skill. Individuals with autism spectrum disorders (ASD) are impaired in social interaction, show deficits in face and emotion processing, show amygdala abnormalities and display a disadvantage in the perception of social threat. According to the anger superiority hypothesis, angry faces capture attention faster than happy faces in individuals with a history of typical development [Hansen, C. H., & Hansen, R. D. (1988). Finding the face in the crowd: An anger superiority effect. Journal of Personality and Social Psychology, 54(6), 917–924]. We tested threat detection abilities in ASD using a facial visual search paradigm. Participants were asked to detect an angry or happy face image in an array of distracter faces. A threat-detection advantage was apparent in both groups: participants showed faster and more accurate detection of threatening over friendly faces. Participants with ASD showed similar reaction time, but decreased overall accuracy compared to controls. This provides evidence for less robust, but intact or learned implicit processing of basic emotions in ASD.     

Conscious and Preconscious Uses of Memory in Patients with Depressive and Somatoform Disorders

This study investigated whether conscious and preconscious memory features contribute to discrimination between depressive and somatoform disorders. Thirty-one participants fulfilling the diagnostic criteria for a somatoform disorder and 28 participants fulfilling the criteria for depression were examined within the framework of the process–dissociation paradigm using neutral, health-threatening, and general threatening words in a lexical decision task. Parameters of conscious memory, preconscious memory, and chance were used to compare memory features of both the groups. There was an inverse relationship between conscious and preconscious memory effects for health-threatening stimuli in the group of patients with somatoform disorders but not in the group of depressive patients. Patients with somatoform disorders showed a significantly lower level of conscious memory for health-threatening stimuli than depressive participants. Compared to depressive patients, a more dynamic relationship between decreased conscious and increased preconscious memory for health-related stimuli seems to be characteristic for patients with somatoform disorders.     

Perception and recall of aversive material as a function of personality type

Relationships between personality dimensions of extraversion (E), neuroticism (N), psychoticism (P) and barrier (B) and patterns of psychophysiological responding during exposure to and subsequent recall of aversive and non-aversive material were investigated. Sixteen male volunteers were asked to recall the critical features of 10 film segments containing either neutral or aversive material. Heart rate (HR), skin conductance (SC) and electromyographic (EMG) responses were recorded throughout the session. Analysis showed that during exposure to aversive material, high BE Ss recorded high levels of autonomic responding and low levels of muscle tension, while during recall, they showed reduced autonomic activity and significantly higher levels of muscle tension. Low BE Ss showed significantly higher levels of muscle tension during film presentation and significantly lower levels during recall, with little change in autonomic reactivity between treatments. Recall data indicate that high BE Ss had significantly better recall under all conditions. N and P differences were unrelated to patterns of psychophysiological responding or efficiency of recall.     

Somatoforme Störungen

The therapy of somatoform disorders should focus on the reduction of physical symptoms. A constant improvement of these symptoms is not possible without the development of the body-self and the body-image, because serious somatoform disorders are always connected with problems of the self-structure, especially of the body-self and the body-image. A treatment approach is presented in a case study.     

Poor hand-pointing to sounds in right brain-damaged patients: not just a problem of spatial-hearing

We asked 22 right brain-damaged (RBD) patients and 11 elderly healthy controls to perform hand-pointing movements to free-field unseen sounds, while modulating two non-auditory variables: the initial position of the responding hand (left, centre or right) and the presence or absence of task-irrelevant ambient vision. RBD patients suffering from visual neglect, unlike RBD patients without neglect and healthy controls, showed a systematic rightward error in sound localisation, which was modulated by the non-auditory variables. Localisation errors were exacerbated by initial hand-position to the right of the body-midline, and reduced by the leftwards initial hand-position. Moreover, for the visual neglect patients, mere presence of ambient vision worsened localisation errors. These results demonstrate that although hand-pointing to sounds has often been considered a straightforward approach to investigate sound-localisation abilities in brain-damaged patients, in some patients it may actually reveal localisation deficits that reflect a combination of impaired spatial-hearing and spatial biases from other sensory modalities (i.e., vision and proprioception).