眼跳的研究范式及其主要认知功能

眼跳运动系统为研究者探索行为的认知控制机制提供了有力工具。已有研究发现,很多认知过程会影响不同类型眼跳任务中的眼跳参数。在系统梳理已有研究的基础上,从以下4个方面系统阐述和评价了眼跳运动的研究范式和主要认知功能：（1）视觉导向眼跳的研究范式和变式及其认知功能,包括空白/重叠效应、分心物效应、提示效应、学习效应等;（2）预测性眼跳的研究范式和认知控制,涉及神经生物钟理论、视空间工作记忆、指导语等;（3）记忆导向眼跳的研究范式和变式及其认知控制,包括分心物效应、年龄效应、视空间工作记忆的抑制效应、注意等;（4）反向眼跳的研究范式和变式及其认知控制,包括反向眼跳抑制、眼跳决策信号竞争整合模型、工作记忆容量、注意、错误监控、学习、奖励和年龄效应等。最后,结合已有研究范式对未来眼跳研究的趋势和需解决的问题进行了展望。     

当前阅读眼动研究的几个主要问题

当前阅读眼动研究主要想解决以下几个问题：（1）阅读中的眼动主要受语言的低水平因素影响还是受语言的高水平因素影响;（2）眼跳过程中信息加工是完全被抑制还是部分被抑制;（3）眼动过程中词义的加工方式是平行的还是系列的。     

自主控制眼跳：实验范式、神经机制和应用

自主控制眼跳是眼跳类型之一。自主控制眼跳实验范式为研究各种脑损伤,神经疾病和精神失调提供了一种新的研究手段,为研究眼跳的神经机制以及反应抑制、空间工作记忆等高级认知功能提供了重要的方法。文章介绍了自主控制眼跳的两种实验范式：反向眼跳和记忆导向眼跳,阐述了自主控制眼跳的神经机制及其实验范式的应用,指出自主控制眼跳实验范式为评定精神分裂症等脑功能失调病人的神经功能状态提供了重要的信息,为研究各种脑功能失调和精神疾病提供了重要的研究方法。今后的研究趋势是眼跳研究与神经成像技术和临床观察相结合     

阅读中的眼动控制理论与SWIFT模型

随着眼动研究的深入,近年来研究者受注意梯度指导理论影响,结合心理学的最新发展以及在相关实验研究的基础上提出了新的理论模型,其中最具代表性的是SWIFT模型。SWIFT模型遵循3条基本原则：（1）一定注意范围内的分布式词汇加工;（2）眼跳计划和目标选择的分离;（3）伴随中央凹目标抑制的眼跳机制。在构架上,该模型主要有两大功能模块：词汇加工和眼跳编程     

任务信息通达对视觉表象眼动的影响

通过两个实验探讨了视觉表象任务信息的通达对表象加工眼动的影响。结果表明, 在低通达条件下, 表象任务的眼动复制了知觉任务的眼动; 随着表象任务信息通达水平的提高, 眼动的注视点平均持续时间、平均眼跳距离和平均眼跳时间会发生规律性变化; 眼动控制与任务信息通达水平对表象眼动的影响存在不同的机制。实验结果佐证了眼动在视觉表象中起机能性作用的观点。     

孤独症谱系障碍患者对种族情境中本异族面孔的眼动模式

本研究采用眼动技术探讨孤独症谱系障碍(ASD)患者对背景中的本异族面孔的加工特点。研究采用2（组别）×2（面孔种族）×3（背景）的混合设计,让16名16-25岁的ASD患者和17名生理年龄匹配的正常人完成变化检测任务,并记录他们的眼动。结果显示：与正常人相比,ASD患者的面孔辨别力更低;他们的眼动呈现更多的面孔-背景眼跳和更多的上下半脸眼跳;两组被试的上下半脸眼跳的次数受到面孔种族以及面孔和背景是否一致的影响。结论：在行为指标上,正常人出现了本族效应,而ASD患者没有出现本族效应;在眼动上,ASD患者呈现与正常人相似的面孔注视时间,但比正常人呈现更多的眼跳。面孔的背景影响了面孔辨别力以及上下半脸眼跳轨迹。     

阅读不同颜色中、英文时的眼动特征

采用眼动实验方法,对20名大学生阅读不同颜色中、英文材料时的眼动特征进行考察。结果发现：（1）颜色对中、英文阅读成绩影响趋势一致,红色成绩最好,黄色最差;（2）颜色对被试阅读眼动指标影响差异显著：注视次数上,红色和黑色最多;注视时间上,红色最短;眼跳距离上,黄色最长;注视频率上,黄色最低。     

弈棋风格的眼动证据

以围棋业余棋手为被试,采用2（大局观：高分、低分）×2（机敏轻灵：高分、低分）的被试间设计,通过眼动分析技术来探寻机敏轻灵和大局观两个弈棋风格维度存在的眼动证据。结果表明：（1）机敏轻灵维度的高低可以从平均注视持续时间、平均眼跳幅度和注视次数三个眼动特征上加以区分;（2）大局观维度存在兴趣区数目、回视次数、眼跳次数、注视次数和平均注视持续时间等五个眼动指标。研究认为,眼动指标为弈棋风格的机敏轻灵和大局观两个维度的存在提供了客观证据。     

真实场景搜索中的眼动返回抑制

眼动返回抑制是指眼睛返回至先前注视过的位置(客体)时眼跳潜伏期长、可能性低的一种抑制现象。近年来, 研究者对真实场景搜索中的眼动返回抑制进行了深入的研究。本文介绍了相关研究的经典实验范式、主要发现及其理论解释, 探讨了眼动返回抑制的容量、眼动返回抑制是否具有任务特异性、场景搜索中是否存在眼动返回促进以及眼动返回抑制的神经基础等问题, 并指出未来该领域研究的方向和途径。     

视觉搜索过程中的眼跳及其机制

该文对视觉搜索过程中的眼跳及其时间进程、神经机制及相关的理论与模型等方面研究进行了回顾。发现内外源性眼跳得到了研究者的普遍关注,对眼运动记忆、返回抑制及眼跳时间进程的研究尚存在分歧。关于眼跳的神经机制,额叶眼动区与上丘分别被认为是眼跳的关键区与指令发出者。尽管不同的眼跳理论与模型对眼跳现象给出了各自的解释,但都不尽完善,尚需对这些理论进行整合或者提出新的解释模型。文章还对未来的研究进行了展望     

Neurophysiology and neuroanatomy of reflexive and volitional saccades: evidence from studies of humans

This review provides a summary of the contributions made by human functional neuroimaging studies to the understanding of neural correlates of saccadic control. The generation of simple visually guided saccades (redirections of gaze to a visual stimulus or pro-saccades) and more complex volitional saccades require similar basic neural circuitry with additional neural regions supporting requisite higher level processes. The saccadic system has been studied extensively in non-human (e.g., single-unit recordings) and human (e.g., lesions and neuroimaging) primates. Considerable knowledge of this system’s functional neuroanatomy makes it useful for investigating models of cognitive control. The network involved in pro-saccade generation (by definition largely exogenously-driven) includes subcortical (striatum, thalamus, superior colliculus, and cerebellar vermis) and cortical (primary visual, extrastriate, and parietal cortices, and frontal and supplementary eye fields) structures. Activation in these regions is also observed during endogenously-driven voluntary saccades (e.g., anti-saccades, ocular motor delayed response or memory saccades, predictive tracking tasks and anticipatory saccades, and saccade sequencing), all of which require complex cognitive processes like inhibition and working memory. These additional requirements are supported by changes in neural activity in basic saccade circuitry and by recruitment of additional neural regions (such as prefrontal and anterior cingulate cortices). Activity in visual cortex is modulated as a function of task demands and may predict the type of saccade to be generated, perhaps via top-down control mechanisms. Neuroimaging studies suggest two foci of activation within FEF - medial and lateral - which may correspond to volitional and reflexive demands, respectively. Future research on saccade control could usefully (i) delineate important anatomical subdivisions that underlie functional differences, (ii) evaluate functional connectivity of anatomical regions supporting saccade generation using methods such as ICA and structural equation modeling, (iii) investigate how context affects behavior and brain activity, and (iv) use multi-modal neuroimaging to maximize spatial and temporal resolution.     

Neurophysiology and neuroanatomy of reflexive and volitional saccades: Evidence from studies of humans

This review provides a summary of the contributions made by human functional neuroimaging studies to the understanding of neural correlates of saccadic control. The generation of simple visually guided saccades (redirections of gaze to a visual stimulus or pro-saccades) and more complex volitional saccades require similar basic neural circuitry with additional neural regions supporting requisite higher level processes. The saccadic system has been studied extensively in non-human (e.g., single-unit recordings) and human (e.g., lesions and neuroimaging) primates. Considerable knowledge of this system’s functional neuroanatomy makes it useful for investigating models of cognitive control. The network involved in pro-saccade generation (by definition largely exogenously-driven) includes subcortical (striatum, thalamus, superior colliculus, and cerebellar vermis) and cortical (primary visual, extrastriate, and parietal cortices, and frontal and supplementary eye fields) structures. Activation in these regions is also observed during endogenously-driven voluntary saccades (e.g., anti-saccades, ocular motor delayed response or memory saccades, predictive tracking tasks and anticipatory saccades, and saccade sequencing), all of which require complex cognitive processes like inhibition and working memory. These additional requirements are supported by changes in neural activity in basic saccade circuitry and by recruitment of additional neural regions (such as prefrontal and anterior cingulate cortices). Activity in visual cortex is modulated as a function of task demands and may predict the type of saccade to be generated, perhaps via top-down control mechanisms. Neuroimaging studies suggest two foci of activation within FEF - medial and lateral - which may correspond to volitional and reflexive demands, respectively. Future research on saccade control could usefully (i) delineate important anatomical subdivisions that underlie functional differences, (ii) evaluate functional connectivity of anatomical regions supporting saccade generation using methods such as ICA and structural equation modeling, (iii) investigate how context affects behavior and brain activity, and (iv) use multi-modal neuroimaging to maximize spatial and temporal resolution.     

刺激的视觉显著性和奖赏价值对眼跳的影响

本研究旨在探索刺激的视觉显著性和奖赏价值分别在协同和竞争的条件下对眼跳过程的影响。实验材料为成对的Gabor图案,要求被试选择具有更高奖赏价值的图案,并记录下其眼动过程。实验分为协同条件和竞争条件。结果发现,在不同实验条件下,奖赏价值对眼跳命中率和潜伏期均存在显著效应;视觉显著性的效应则在不同实验条件下出现了分离。刺激驱动过程和目标驱动过程对眼动行为的影响可能是互相区别的两种不同模式。     

Effects of direct and averted gaze on the subsequent saccadic response

The saccadic latency to visual targets is susceptible to the properties of the currently fixated objects. For example, the disappearance of a fixation stimulus prior to presentation of a peripheral target shortens saccadic latencies (the gap effect). In the present study, we investigated the influences of a social signal from a facial fixation stimulus (i.e., gaze direction) on subsequent saccadic responses in the gap paradigm. In Experiment 1, a cartoon face with a direct or averted gaze was used as a fixation stimulus. The pupils of the face were unchanged (overlap), disappeared (gap), or were translated vertically to make or break eye contact (gaze shift). Participants were required to make a saccade toward a target to the left or the right of the fixation stimulus as quickly as possible. The results showed that the gaze direction influenced saccadic latencies only in the gaze shift condition, but not in the gap or overlap condition; the direct-to-averted gaze shift (i.e., breaking eye contact) yielded shorter saccadic latencies than did the averted-to-direct gaze shift (i.e., making eye contact). Further experiments revealed that this effect was eye contact specific (Exp. 2) and that the appearance of an eye gaze immediately before the saccade initiation also influenced the saccadic latency, depending on the gaze direction (Exp. 3). These results suggest that the latency of target-elicited saccades can be modulated not only by physical changes of the fixation stimulus, as has been seen in the conventional gap effect, but also by a social signal from the attended fixation stimulus.     

Behavioral measures of saccade latency and inhibition in manifest and premanifest Huntington's disease

Initiation and inhibition of saccadic eye movements has been shown to be impaired in patients with Huntington's disease (HD) and premanifest gene carriers (PMGC), and may provide biomarkers useful in tracking phenotypic change. Computerized behavioral tests of prosaccade latency and disinhibition presented to 31 non-gene carriers (NGC), 25 PMGC, and 12 HD patients. These tests provided quantitative performance measures without use of eye-tracking equipment. Significant differences on saccade tests were found, with PMGC intermediate between NGC and HD patients. Saccade latency discriminated PMGC from NGC, whereas saccade disinhibition discriminated PMGC from HD patients. Results suggest utility of behavioral saccade measures as premanifest indicators of phenoconversion in HD.     

Awareness of the saccade goal in oculomotor selection: Your eyes go before you know

The aim of the present study was to investigate how saccadic selection relates to people’s awareness of the saliency and identity of a saccade goal. Observers were instructed to make an eye movement to either the most salient line segment (Experiment 1) or the only right-tilted element (Experiment 2) in a visual search display. The display was masked contingent on the first eye movement and after each trial observers indicated whether or not they had correctly selected the target. Whereas people’s awareness concerning the saliency of the saccade goal was generally low, their awareness concerning the identity was high. Observers’ awareness of the saccade goal was not related to saccadic performance. Whereas saccadic selection consistently varied as a function of saccade latency, people’s awareness concerning the saliency or identity of the saccade goal did not. The results suggest that saccadic selection is primarily driven by subconscious processes.     

Validation of a Behavioral Approach for Measuring Saccades in Parkinson's Disease

Speed and control of saccades are related to disease progression and cognitive functioning in Parkinson's disease (PD). Traditional eye-tracking complexities encumber application for individual evaluations and clinical trials. The authors examined psychometric properties of standalone tasks for reflexive prosaccade latency, volitional saccade initiation, and saccade inhibition (antisaccade) in a heterogeneous sample of 65 PD patients. Demographics had minimal impact on task performance. Thirty-day test–retest reliability estimates for behavioral tasks were acceptable and similar to traditional eye tracking. Behavioral tasks demonstrated concurrent validity with traditional eye-tracking measures; discriminant validity was less clear. Saccade initiation and inhibition discriminated PD patients with cognitive impairment. The present findings support further development and use of the behavioral tasks for assessing latency and control of saccades in PD.     

Self-bias modulates saccadic control

We present novel data on the role of attention in eliciting enhanced processing of stimuli associated with self. Participants were required to make pro- or anti-saccades according to whether learned shape–label pairings matched or mismatched. When stimuli matched participants were required to make an anti-saccade, and when the stimuli mismatched a pro-saccade was required. We found that anti-saccades were difficult to make to stimuli associated with self when compared to stimuli associated with a friend and a stranger. In contrast, anti-saccades to friend-stimuli were easier to make than anti-saccades to stranger-stimuli. In addition, a correct anti-saccade to a self-associated stimulus disrupted subsequent pro-saccade trials, relative to when the preceding anti-saccade was made to other stimuli. The data indicate that self-associated stimuli provide a strong cue for explicit shifts of attention to them, and that correct anti-saccades to such stimuli demand high levels of inhibition (which carries over to subsequent pro-saccade trials). The self exerts an automatic draw on attention.     

Giving subjects the eye and showing them the finger: socio-biological cues and saccade generation in the anti-saccade task

Pointing with the eyes or the finger occurs frequently in social interaction to indicate direction of attention and one's intentions. Research with a voluntary saccade task (where saccade direction is instructed by the colour of a fixation point) suggested that gaze cues automatically activate the oculomotor system, but non-biological cues, like arrows, do not. However, other work has failed to support the claim that gaze cues are special. In the current research we introduced biological and non-biological cues into the anti-saccade task, using a range of stimulus onset asynchronies (SOAs). The anti-saccade task recruits both top-down and bottom-up attentional mechanisms, as occurs in naturalistic saccadic behaviour. In experiment 1 gaze, but not arrows, facilitated saccadic reaction times (SRTs) in the opposite direction to the cues over all SOAs, whereas in experiment 2 directional word cues had no effect on saccades. In experiment 3 finger pointing cues caused reduced SRTs in the opposite direction to the cues at short SOAs. These findings suggest that biological cues automatically recruit the oculomotor system whereas non-biological cues do not. Furthermore, the anti-saccade task set appears to facilitate saccadic responses in the opposite direction to the cues.