抑郁个体对情绪面孔的返回抑制能力不足

探讨抑郁对情绪面孔返回抑制能力的影响。以贝克抑郁量表、自评抑郁量表、CCMD-3和汉密顿抑郁量表为工具筛选出了正常对照组、抑郁康复组和抑郁患者组各17名被试进行了真人情绪面孔线索-靶子任务的行为学实验和事件相关电位(ERP)实验。在线索靶子范式中, 靶子在线索消失后出现, 被试对靶子的位置作出反应。行为学实验显示线索靶子间隔时间(stimulus onset asynchronies, SOA)为14ms时, 正常对照组对中性面孔有返回抑制效应, 抑郁康复组对所有面孔均存在返回抑制效应, 患者组对愤怒、悲伤面孔和中性面孔存在返回抑制效应; SOA为250ms时三组被试均对悲伤面孔存在返回抑制能力不足, 以患者组最突出, 康复组对高兴面孔存在返回抑制能力不足; SOA为750ms时正常组对悲伤面孔存在返回抑制效应, 康复组对高兴和悲伤面孔存在返回抑制能力不足, 患者组对悲伤面孔存在返回抑制能力不足, 对愤怒面孔存在返回抑制效应。在SOA为750ms的条件下, ERP波形特点为正常组对高兴面孔线索P3波幅大于其他组, 对高兴面孔无效提示P1波幅小于其他面孔, 对悲伤面孔有效提示P1波幅小于高兴面孔, 对高兴面孔有效提示P3波幅大于患者组, 对悲伤面孔无效提示P3波幅大于其他组; 康复组对悲伤面孔线索P3波幅大于其他面孔, 对高兴面孔有效提示P3波幅大于患者组, 对悲伤面孔无效提示P3波幅小于正常组; 患者组对悲伤面孔线索P1波幅大于其他组、P3波幅大于其他面孔, 对悲伤面孔无效提示P3波幅小于正常组, 高兴面孔有效提示P3波幅小于其他组。提示抑郁患者对负性刺激有返回抑制能力不足, 这种对负性刺激抑制能力的缺失导致抑郁个体难以抗拒负性事件的干扰而受到不良情绪状态的困扰, 所以他们可能更多的体验到抑郁情绪, 并致使抑郁持续和发展。而抑郁康复个体对高兴、悲伤面孔均有返回抑制能力不足, 这让康复个体能同时感受到正、负性刺激, 从而能保持一种认知和情绪上特定的平衡。     

阈下抑郁个体对负性情绪刺激的注意解脱困难

本研究拟采用点探测范式及不同情绪内容的面孔刺激（高兴、中性、悲伤和愤怒）考察阈下抑郁个体的负性注意偏向及其内在机制。点探测任务中情绪面孔配对呈现（负性-中性、正性-中性）,配对面孔中的情绪线索位置与靶刺激的位置构成负性一致/不一致和正性一致/不一致条件,同时实验中加入“中性-中性”面孔线索作为一致和不一致条件的对比基线来考察注意偏向的内在机制。结果发现,阈下抑郁个体在负性不一致条件下的反应时显著长于负性一致条件,表明阈下抑郁个体具有对负性刺激的注意偏向;进一步比较发现,阈下抑郁个体在负性不一致条件下的反应时显著的长于“中性-中性”基线条件,而负性一致条件与基线之间差异不显著,表明阈下抑郁个体的负性注意偏向为对负性刺激的注意解脱困难。结果另发现,阈下抑郁个体未能像无抑郁对照组个体表现出对正性刺激的注意偏向。结果表明,处于阈下抑郁状态的个体表现出对负性刺激的注意偏向,具体为对负性刺激的注意解脱困难,其原因可能是由于阈下抑郁个体在注意控制和情绪调节功能上的紊乱。     

不同抑郁状态个体对情绪面孔的评价研究

目的:为探讨不同抑郁状态个体对情绪面孔的效价评价情况。方法:以BDI、SDS、CCMD-3和汉密顿抑郁量表为工具筛选出42名正常对照组、54名抑郁情绪组、17名抑郁康复组和24名抑郁患者组成员,所有被试完成情绪面孔的效价评价任务。结果:发现抑郁患者组和抑郁情绪组对高兴面孔的评价分数显著低于其他两组(F=7.427,p=0.000);抑郁患者组和抑郁康复组对悲伤面孔的评价分数显著低于其他两组(F=4.956,p=0.003);抑郁患者组和抑郁康复组在情绪评价任务中对高兴和中性面孔的反应时显著长于其他两组(F=13.735,p=0.000;F=18.008,p=0.000),对悲伤面孔的反应时与其他两组无显著差异(p>0.05),抑郁患者组对中性面孔的反应时显著长于悲伤面孔(F=4.240,p=0.018)。结论:抑郁个体对正性刺激存在感知缺陷,对负性刺激存在夸大加工倾向和加工易化效应,其中前者是抑郁的状态特征,后两者是抑郁的特质特征。     

高特质愤怒个体对负性情绪面孔注意偏向的实验研究

摘 要：目的 探讨高特质愤怒个体是否对负性情绪面孔有注意偏向。方法 采用点探测任务,比较高低特质愤怒个体（高特质愤怒组23人,低特质愤怒组23人）对不同性质情绪面孔同异侧探测符号反应时的差异。结果 重复测量方差分析发现存在面孔性质边缘主效应（F=2.462,p=.073）及组别与面孔性质的交互效应,探测位置主效应（F=5.089,p=.029）及组别与探测位置的交互效应,组别、面孔性质与探测位置的交互效应。进一步分析发现,高特质愤怒组对愤怒面孔同侧探测刺激反应时显著快于异侧反应时[（386.12±50.09）ms VS.(403.33±59.39)ms,F=17.050,p=.000],快乐面孔同侧探测刺激反应时显著慢于异侧反应时[（396.88±53.87）ms VS.(38.78±41.06)ms,F=18.200,p=.000）],低特质愤怒组被试不同性质面孔同异侧反应时无显著差异。结论 高特质愤怒个体对与愤怒相关刺激存在注意偏向。     

抑郁情绪大学生反应抑制的眼动特点

本研究采用反眼动实验范式,通过BDI和 SDS量表筛选11名抑郁情绪组和12名正常对照组被试,以高兴、中性和悲伤面孔图片作为实验材料,旨在探讨抑郁情绪大学生对情绪刺激的眼动抑制能力。结果发现：抑郁情绪组的正确眼跳反应时慢于正常组;反朝向眼跳任务中,抑郁情绪组在情绪面孔图片,尤其是悲伤面孔图片上的错误率比正常组高。研究表明,抑郁情绪个体的认知加工速度慢于正常个体,且对情绪面孔,尤其对悲伤面孔存在抑制缺陷。     

不同线索下特质焦虑个体的返回抑制

焦虑与注意偏向的研究是近年来情绪与认知领域的热点。为探讨特质焦虑个体的注意偏向特点及其返回抑制能力是否受不同线索的调节, 采用特质焦虑量表筛选高特质焦虑大学生29名, 低特质焦虑大学生28名完成线索-靶子任务。要求被试在提示线索消失后, 对位置进行快而准地辨别反应, 分别探索中性和情绪性提示线索下被试的返回抑制。结果发现：(1)在中性线索条件下, 高焦虑个体平均反应时慢于低焦虑个体。(2) 在情绪线索条件下, 高焦虑个体在负性线索下的反应时小于在正性线索下的反应时; 高、低焦虑个体在各种SOA条件下均出现了返回抑制, 但各组返回抑制量受到情绪线索的调节：在正性情绪线索条件下, 两组返回抑制量没有显著差异; 在负性情绪线索下, 高焦虑个体返回抑制量显著小于低焦虑个体。这表明, (1)焦虑个体的注意偏向受到刺激信息的影响：只对负性情绪线索出现注意警觉; (2)只有在涉及负性情绪信息时高、低焦虑个体返回抑制能力才有差异, 高焦虑个体存在对负性情绪线索的抑制困难。     

中英双语者情绪注意偏向中的双语优势效应

采用改进的点–探测范式,考察熟练双语者在情绪注意偏向中对情绪信息加工的优势效应及该效应产生的原因。采用2（熟练双语者和非熟练双语者）×3（靶刺激与消极词汇出现的位置一致、不一致和中性条件）×2（线索呈现时间为100 ms和400 ms）的混合实验设计,记录被试对靶子的按键反应时和错误率。结果发现：线索呈现100 ms和400 ms时,两组被试在注意定向分数上无显著差异;线索呈现100 ms时,两组被试的注意解除分数无显著差异;线索呈现400 ms时,熟练双语者的注意解除分数显著小于非熟练双语者。结果表明,在情绪注意偏向任务中,熟练双语者比非熟练双语者表现出了对情绪词汇信息更好的注意抑制控制能力,体现出对情绪信息加工的双语优势效应,产生这一优势效应的原因是熟练双语者在注意的晚期阶段比非熟练双语者具有更好的情绪信息注意解除能力。     

哭泣表情面孔的注意偏向:眼动的证据

研究采用双选择Oddball范式和线索-靶子范式,并结合眼动技术,以微笑、哭泣和中性表情面孔为刺激材料,综合考察哭泣表情面孔在识别和解离过程中的注意偏向。研究发现:在识别阶段,哭泣表情面孔的识别正确率和反应速度都显著优于微笑表情面孔,进一步的兴趣区注视偏向分析发现,哭泣和微笑表情面孔的注视模式既具有一致的规律,又存在细微的差异;在解离阶段,返回抑制受线索表情类型的影响,在有效线索条件下,哭泣表情线索呈现后个体对目标刺激的平均注视时间和眼跳潜伏期都显著短于其它表情线索。表明哭泣表情面孔在识别和解离过程中具有不同的注意偏向表现,在识别阶段表现为反应输出优势和注视模式上的一致性与差异性;在解离阶段表现为有效线索条件下,对目标刺激定位和视觉加工的促进作用。     

自我威胁刺激对返回抑制的影响

使用线索-靶子范式,分别将面孔刺激作为线索(实验1)和靶子(实验2)呈现,考察自我扭曲面孔对返回抑制的影响。结果发现:自我扭曲面孔为线索时,与他人扭曲、他人中性面孔产生了实验性分离,自我扭曲面孔的返回抑制效应量最小;自我扭曲面孔为靶子时,返回抑制消失。研究结果揭示:以自我扭曲面孔为代表的自我威胁刺激激活了威胁性自我概念,缩小了注意搜索范围,可能是导致人际紧张的潜在自我认知机制。     

返回抑制和情绪信息注意偏向的竞争：来自眼动的证据

返回抑制与情绪注意偏向是研究视觉注意的两个视角,二者的优先性一直存在争议。本研究采用线索—靶子范式,在靶子位置呈现情绪图片,结合眼动技术,对整体反应时进行分解,探讨情绪信息与实验任务相关条件下的返回抑制和情绪注意偏向。结果发现：返回抑制效应出现;情绪信息与实验任务的相关性影响了个体对情绪信息早期的注意捕获;有效线索对情绪信息的加工抑制有限,情绪信息的加工表现出了自动化倾向。     

返回抑制过程中情绪面孔加工优先：ERPs研究

返回抑制(IOR)是指注意过程中个体对已搜索过的位置进行抑制, 从而在随后该位置上出现目标时发生注意重新定向或反应变慢的过程。本研究使用ERPs技术, 采用线索-靶子范式, 考察了情绪目标辨别任务中IOR的发生过程及二者的神经机制。结果发现, 与无效线索相比, 有效线索下的P1波幅更小, N1波幅更大, 正性、负性面孔N170的波幅比中性面孔大。表明当要求被试做情绪辨别任务时, IOR与对情绪信息的反应之间发生了分离, 表现出情绪加工的优先。这说明IOR和情绪偏向是发生在两种不同神经通路上的适应机制, 也为进一步探究注意与情绪的关系问题提供了来自神经电生理学的证据。     

Lack of an Attention Bias Away From Relatively Negative Faces in Dysphoria Is Not Related to Biased Emotion Identification

Eye-tracking-based attention research has consistently shown a lack of a normative attentional bias away from dysphoric face stimuli in depression, characterizing the attention system of non-depressed individuals. However, this more equal attention allocation pattern could also be related to biased emotion identification, namely, an inclination of depressed individuals to attribute negative emotions to non-negative stimuli when processing mood-congruent stimuli. Here, we examined emotion identification as a possible mechanism associated with attention allocation when processing emotional faces in depression. Attention allocation and emotion identification of participants with high (HD; n = 30) and low (LD; n = 30) levels of depression symptoms were assessed using two corresponding tasks previously shown to yield significant findings in depression, using the same face stimuli (sad, happy, and neutral faces) across both tasks. We examined group differences on each task and possible between-task associations. Results showed that while LD participants dwelled longer on relatively positive faces compared with relatively negative faces on the attention allocation task, HD participants showed no such bias, dwelling equally on both. Trait anxiety did not affect these results. No group differences were noted for emotion identification, and no between-task associations emerged. Present results suggest that depression is characterized by a lack of a general attention bias toward relatively positive faces over relatively negative faces, which is not related to a corresponding bias in emotion identification.     

Emotional and hemispheric asymmetries in shifts of attention: An ERP study

Inhibition of return (IOR) refers to the larger response time to cued targets appearing at long cue-to-target intervals. Given emotion–attention interactions and associated visual field (VF) asymmetries, we examined the effects of emotions and hemispheric processing on object- and location-based IOR. We expected reduced IOR and right hemispheric bias accompanied by differences in event-related potentials (ERPs) including lack of suppression of cued N1 and enhancement of Nd components for sad targets. Reaction times and ERPs were recorded in an exogenous cuing detection task using happy and sad schematic faces. Results revealed reduced IOR for left compared to right VF with sad faces but no such asymmetry for happy faces. Cued N1 amplitudes were suppressed for happy targets but not for sad targets presented to the left VF. Nd amplitudes were enhanced for right-hemispheric sad faces especially with object-based IOR. The results indicate right-hemispheric advantage in the capture of attention by negative emotion especially with object-based selection.     

Emotional and hemispheric asymmetries in shifts of attention: an ERP study

Inhibition of return (IOR) refers to the larger response time to cued targets appearing at long cue-to-target intervals. Given emotion-attention interactions and associated visual field (VF) asymmetries, we examined the effects of emotions and hemispheric processing on object- and location-based IOR. We expected reduced IOR and right hemispheric bias accompanied by differences in event-related potentials (ERPs) including lack of suppression of cued N1 and enhancement of Nd components for sad targets. Reaction times and ERPs were recorded in an exogenous cuing detection task using happy and sad schematic faces. Results revealed reduced IOR for left compared to right VF with sad faces but no such asymmetry for happy faces. Cued N1 amplitudes were suppressed for happy targets but not for sad targets presented to the left VF. Nd amplitudes were enhanced for right-hemispheric sad faces especially with object-based IOR. The results indicate right-hemispheric advantage in the capture of attention by negative emotion especially with object-based selection.     

Attentional biases for negative interpersonal stimuli in clinical depression

An information-processing paradigm was used to examine attentional biases in clinically depressed participants, participants with generalized anxiety disorder (GAD), and nonpsychiatric control participants for faces expressing sadness, anger, and happiness. Faces were presented for 1000 ms, at which point depressed participants had directed their attention selectively to depression-relevant (i.e., sad) faces. This attentional bias was specific to the emotion of sadness; the depressed participants did not exhibit attentional biases to the angry or happy faces. This bias was also specific to depression; at 1000 ms, participants with GAD were not attending selectively to sad, happy, or anxiety-relevant (i.e., angry) faces. Implications of these findings for both the cognitive and the interpersonal functioning of depressed individuals are discussed and directions for future research are advanced.     

攻击性信息对脆弱型高自尊大学生返回抑制的影响机制

为考察攻击性信息对脆弱型高自尊大学生返回抑制的影响机制,本研究采用线索靶子范式,分别将攻击性及中性词汇作为靶子（实验1）和线索（实验2）呈现。实验1发现,脆弱型和安全型高自尊组对攻击性信息均存在注意捕获,从而使攻击性信息的返回抑制量降低。实验2发现,脆弱型高自尊组对攻击性信息存在注意解除困难,从而使攻击性信息的返回抑制量降低。脆弱型高自尊大学生对攻击性信息存在过多的注意维持,降低了视觉搜索效率,这可是其好发攻击性行为的潜在认知加工机制。     

Attentional Processing of Threat in Bipolar Disorder: Going Beyond Mood-Congruency

Emotional processing in bipolar disorder (BD) entails a complex attentional pattern not merely restricted to happy or sad biases, but also directed towards threatening information. This study examined threat-related bias on attentional orienting when participants were not instructed about the presentation of emotional stimuli (i.e., implicit instructions). An emotional dot-probe task in which an emotional face (i.e., threat, sad, happy) is simultaneously displayed with a neutral face was applied to BD individuals in their different episodes: mania (n?=?26), depression (n?=?24), and euthymia (n?=?28) as well as to a group of healthy controls (n?=?28). Symptomatic BD patients (i.e., in a manic or depressive episode) showed an attentional orienting bias toward threatening faces but not for happy or sad faces, while euthymic BD patients did not exhibit any attentional bias for emotional stimuli. A bias toward happy faces was found in the control group. Threat-related bias was not related to the severity of affective and anxiety symptoms in BD. When attention is not explicitly directed to emotional information, threat-related bias may characterize attentional orienting during mania and depression, but may be attenuated during euthymia.

     

暂时建立的自我参照线索对返回抑制的影响

采用经典线索-靶子范式,考察了暂时建立的自我参照线索对返回抑制（inhibition of return, IOR）效应量的调节作用。结果发现,在暂时建立的朋友参照线索或无意义线索条件下均产生了IOR效应,但是在暂时建立的自我参照线索条件下IOR效应没有出现,这是因为相比暂时建立的朋友参照线索或无意义线索,被试对呈现在暂时建立的自我参照线索后的靶刺激的反应更快。结果表明,自我相关信息能够削弱IOR的效应量,并为IOR是一种进化适应性的视觉搜索促进机制提供了新的证据。