Enhanced development of auditory change detection in musically trained school‐aged children: a longitudinal event‐related potential study

Adult musicians show superior auditory discrimination skills when compared to non‐musicians. The enhanced auditory skills of musicians are reflected in the augmented amplitudes of their auditory event‐related potential (ERP) responses. In the current study, we investigated longitudinally the development of auditory discrimination skills in musically trained and nontrained individuals. To this end, we recorded the mismatch negativity (MMN) and P3a responses from children who play a musical instrument and age‐matched children with no musical training at ages 7, 9, 11, and 13. Basic auditory processing was investigated by recording ERPs in the Multi‐Feature Paradigm that included frequency, duration, intensity, location, and gap deviants. The detection of musically more relevant sound changes was examined in an oddball paradigm with major chords as standards and minor chords as deviants. The musically trained children showed larger increase in MMN and P3a amplitudes with age for the chord deviants than the control children. There was also a strong trend (p = .054) for larger increase in MMN amplitude in the musically trained children for the location deviant. As no group differences in response amplitudes were evident at the early stages of the training, our results suggest that the superior neural auditory discrimination in adult musicians is due to training and not pre‐existing differences between musicians and non‐musicians.     

Effects of visual attentional load on low-level auditory scene analysis

The sharing of processing resources between the senses was investigated by examining the effects of visual task load on auditory event-related brain potentials (ERPs). In Experiment 1, participants completed both a zero-back and a one-back visual task while a tone pattern or a harmonic series was presented. N1 and P2 waves were modulated by visual task difficulty, but neither mismatch negativity (MMN) elicited by deviant stimuli from the tone pattern nor object-related negativity (ORN) elicited by mistuning from the harmonic series was affected. In Experiment 2, participants responded to identity (what) or location (where) in vision, while ignoring sounds alternating in either pitch (what) or location (where). Auditory ERP modulations were consistent with task difficulty, rather than with task specificity. In Experiment 3, we investigated auditory ERP generation under conditions of no visual task. The results are discussed with respect to a distinction between process-general (N1 and P2) and processspecific (MMN and ORN) auditory ERPs.     

失匹配负波研究的主要争论与动向

失匹配负波(MMN)是小概率刺激ERP减大概率刺激ERP的差异负波,可由Oddball范式和多特征选择范式获得。近年研究发现MMN不仅存在于听觉通道,还存在于其他通道,且其波幅可反映自动加工,潜伏期则可反映控制加工。MMN可能反映与错误负波ERN相同或相似的加工过程,MMN反映社会认知加工的观点还需进一步研究。未来研究需整合高时间和空间精度技术,从行为和认知神经科学多层面来开展复杂社会刺激的研究,以便阐明MMN可能反映社会认知加工的性质,并在此基础上增强对MMN与ERN的比较研究。     

Event-related brain potentials reflect traces of echoic memory in humans

In sequences of identical auditory stimuli, infrequent deviant stimuli elicit an event-related brain potential component called mismatch negativity (MMN). MMN is presumed to reflect the existence of a memory trace of the frequent stimulus at the moment of presentation of the infrequent stimulus. This hypothesis was tested by applying the recognition-masking paradigm of cognitive psychology. In this paradigm, a masking sound presented shortly before or after a test stimulus diminishes the recognition memory of this stimulus, the more so the shorter the interval between the test and masking stimuli. This interval was varied in the present study. It was found that the MMN amplitude strongly correlated with the subject’s ability to discriminate between frequent and infrequent stimuli. This result strongly suggests that MMN providesa measure for a trace of sensory memory, and further, that with MMN, this memory can be studied without performance-related distortions.     

Does a self management intervention lower distress in woman diagnosed with breast cancer?1

Psychological distress is particularly common with any cancer diagnosis. This paper examined the psychological distress in a cohort of women newly diagnosed with breast cancer and postulates on the underlying theory. A longitudinal study of a cohort of women (n = 147) diagnosed with breast cancer (within the past 1 year), was conducted at University Malaya Medical Centre, Kuala Lumpur. Data were collected at baseline and at post 4‐week intervention. Analysis of variance was conducted to examine for any significant differences in the change‐scores between the experimental group (n = 69) and the control group (n = 78). Using the change scores, analyses of variance showed significant differences between groups for stress, F(1, 140) = 13.68, p < .0001, anxiety F(1, 140) = 8.44, p < .004, and depression, F(1, 140) = 11.57, p < .0001. Levels of stress, anxiety and depression generally decreased significantly in the experimental groups, p < .05, but either maintained or increased in the control group. This study indicates that the level of psychological distress of women with breast cancer can be ameliorated with a 4‐week self‐management intervention. Lower stress levels were also found in women who reported engagement in higher physical activity than women with low physical activity.     

Automatic change detection in vision: Adaptation,memory mismatch,or both? II: Oddball and adaptation effects on event-related potentials

In this study we compared the event-related potentials (ERPs) obtained in two different paradigms: a passive visual oddball paradigm and an adaptation paradigm. The aim of the study was to investigate the relation between the effects of activity decrease following an adaptor (stimulus-specific adaptation) and the effects of an infrequent stimulus within sequences of frequent ones. In Experiment 1, participants were presented with different line textures. The frequent (standard) and rare (deviant) texture elements differed in their orientation. In Experiment 2, windmill pattern stimuli were presented in which the number of vanes differentiated the deviant and standard stimuli. In Experiment 1 the ERP differences elicited between the oddball deviant and the standard were similar to the differences between the ERPs to the nonadapted and adapted stimuli in the adaptation paradigm. In both paradigms the differences appeared as a posterior negativity with the latency of 120–140 ms. This finding demonstrates that the representation of a sequential rule (successive presentation of the standard) and the violation of this rule are not necessary for deviancy effects to emerge. In Experiment 2 (windmill pattern), in the oddball paradigm the difference potentials appeared as a long-lasting negativity. In the adaptation condition, the later part of this negativity (after 200 ms) was absent. We identified the later part of the oddball difference potential as the genuine visual mismatch negativity—that is, an ERP correlate of sequence violations. The latencies of the difference potentials (deviant minus standard) and the endogenous components (P1 and N1) diverged; therefore, the adaptation of these particular ERP components cannot explain the deviancy effect. Accordingly, the sources contributing to the standard-versus-deviant modulations differed from those related to visual adaptation; that is, they generated distinct ERP components.     

Atypical central auditory speech-sound discrimination in children who stutter as indexed by the mismatch negativity

PurposeRecent theoretical conceptualizations suggest that disfluencies in stuttering may arise from several factors, one of them being atypical auditory processing. The main purpose of the present study was to investigate whether speech sound encoding and central auditory discrimination, are affected in children who stutter (CWS).MethodsParticipants were 10 CWS, and 12 typically developing children with fluent speech (TDC). Event-related potentials (ERPs) for syllables and syllable changes [consonant, vowel, vowel-duration, frequency (F0), and intensity changes], critical in speech perception and language development of CWS were compared to those of TDC.ResultsThere were no significant group differences in the amplitudes or latencies of the P1 or N2 responses elicited by the standard stimuli. However, the Mismatch Negativity (MMN) amplitude was significantly smaller in CWS than in TDC. For TDC all deviants of the linguistic multifeature paradigm elicited significant MMN amplitudes, comparable with the results found earlier with the same paradigm in 6-year-old children. In contrast, only the duration change elicited a significant MMN in CWS.ConclusionsThe results showed that central auditory speech-sound processing was typical at the level of sound encoding in CWS. In contrast, central speech-sound discrimination, as indexed by the MMN for multiple sound features (both phonetic and prosodic), was atypical in the group of CWS. Findings were linked to existing conceptualizations on stuttering etiology.Educational objectives: The reader will be able (a) to describe recent findings on central auditory speech-sound processing in individuals who stutter, (b) to describe the measurement of auditory reception and central auditory speech-sound discrimination, (c) to describe the findings of central auditory speech-sound discrimination, as indexed by the mismatch negativity (MMN), in children who stutter.     

Ankle Intrinsic Stiffness in Subcortical Poststroke Subjects

The authors' purpose was to evaluate bilateral ankle intrinsic stiffness in subcortical poststroke subjects. Ten subcortical poststroke subjects and 10 healthy controls participated in this study. The ankle passive stiffness at 3 different speeds and the electromyographic activity of the soleus, the gastrocnemius, and the tibialis anterior muscles of poststroke contralesional (CONTRA) and ipsilesional (IPSI) limbs and of one limb of healthy subjects were assessed. Ankle electromyographic activity was collected to ensure that reflexive or voluntary muscle activity was not being elicited during the passive movements. A significant interaction was observed between the effects of the limb (IPSI vs. CONTRA vs. control) and ankle position, F(4, 28) = 3.285, p = .025, and between the effects of the limb and the velocity of stretch, F(2, 14) = 4.209, p = .037. While increased intrinsic stiffness was observed in the CONTRA limb of poststroke subjects at ankle neutral position when the passive stretch was applied with a velocity of 1°/s (p = .021), the IPSI limb of poststroke subjects presented increased stiffness at 20º of plantar flexion when the stretch was applied with a velocity of 5°/s (p = .009) when compared to healthy group. Subcortical poststroke subjects present increased intrinsic stiffness in both the CONTRA and IPSI limbs in specific ankle amplitudes.     

Dealing with deviants: The effectiveness of rejection,denial, and apologies on protecting the public image of a group

Public transgressions by group members threaten the public image of a group when outside observers perceive them as representative of the group in general. In three studies, we tested the effectiveness of rejection of a deviant group member who made a racist comment in public, and compared this to several other strategies the group could employ to protect their image. In Study 1 (N = 75) and Study 2 (N = 51), the group was judged less racist after rejecting the deviant than after claiming a non‐racist position or not responding to the transgression. Perceived typicality of the deviant partially mediated this effect in Study 2. In Study 3 (N = 81), the group was judged least racist after forcing the deviant to apologize and as most racist after denying the severity of the transgression. Results also showed a negative side‐effect of rejection. Perceived exclusion of the deviant contributed to a perception of the group as disloyal to its members, which resulted in a less favorable overall group evaluation. Potential benefits and risks of rejection, denial, and apologies are further discussed in the General Discussion. Copyright © 2009 John Wiley & Sons, Ltd.     

Investigating the Constrained Action Hypothesis: A Movement Coordination and Coordination Variability Approach

The purpose of this study was to examine the effects of focus of attention cues on movement coordination and coordination variability in the lower extremity. Twenty participants performed the standing long jump under both internal and external focus of attention conditions. A modified vector coding technique was used to evaluate the influence of attentional focus cues on lower extremity coordination patterns and coordination variability during the jumps. Participants jumped significantly further under an external focus of attention condition compared with an internal focus of attention condition (p = .035, effect size = .29). Focus of attention also influenced coordination between the ankle and knee, F(6, 19) = 2.87, p = .012, effect size = .388, with participants primarily using their knees under the internal focus of attention, and using both their ankles and knees under the external focus of attention. Attentional focus cues did not influence ankle-knee, F(1, 19) = 0.02, p = .98, effect size = .02, or hip-knee, F(1, 19) = 5.00, p = .49, effect size = .16, coordination variability. Results suggest that while attentional focus may not directly influence movement coordination condition, there is still a change in movement strategy resulting in greater jump distances following an external focus of attention.     

Duration of auditory sensory memory in parents of children with SLI: a mismatch negativity study

In a previous behavioral study, we showed that parents of children with SLI had a subclinical deficit in phonological short-term memory. Here, we tested the hypothesis that they also have a deficit in nonverbal auditory sensory memory. We measured auditory sensory memory using a paradigm involving an electrophysiological component called the mismatch negativity (MMN). The MMN is a measure of the brain's ability to detect a difference between a frequent standard stimulus (1000 Hz tone) and a rare deviant one (1200 Hz tone). Memory effects were assessed by varying the inter-stimulus interval (ISI) between the standard and deviant. We predicted that parents of children with SLI would have a smaller MMN than parents of typically developing children at a long ISI (3000 ms), but not at a short one (800 ms). This was broadly confirmed. However, individual differences in MMN amplitude did not correlate with measures of phonological short-term memory. Attenuation of MMN amplitude at the longer ISI thus did not provide unambiguous support for the hypothesis of a reduced auditory sensory memory in parents of affected children. We conclude by reviewing possible explanations for the observed group effects.     

A note on statistical power in multi‐site randomized trials with multiple treatments at each site

We derive the statistical power functions in multi‐site randomized trials with multiple treatments at each site, using multi‐level modelling. An F statistic is used to test multiple parameters in the multi‐level model instead of the Wald chi square test as suggested in the current literature. The F statistic is shown to be more conservative than the Wald statistic in testing any overall treatment effect among the multiple study conditions. In addition, we improvise an easy way to estimate the non‐centrality parameters for the means comparison t‐tests and the F test, using Helmert contrast coding in the multi‐level model. The variance of treatment means, which is difficult to fathom but necessary for power analysis, is decomposed into intuitive simple effect sizes in the contrast tests. The method is exemplified by a multi‐site evaluation study of the behavioural interventions for cannabis dependence.     

Children Exposed to Intra-Familial Violence

Abstract

This investigation examined factors associated with attrition and retention within a sample of children with a history of intra-familial violence referred for outpatient services. The sample included 118 children, aged 4-17 years; of these 64% completed treatment, 20% did not engage in treatment and 16% terminated prematurely. Caregivers reporting high child-related parental distress (F(2, 32) = 3.9, p = 0.03) and high psychological distress (F(2, 70) = 3.3, p = 0.04) were less likely to engage in treatment. Making a child abuse report during assessment or treatment was not found to be associated with treatment engagement or attrition, χ² ₍₂₎= 0.4, p = 0.82. The implications of these findings for clinical practice and treatment outcome research are discussed.     

A National Survey on Multicultural Competence for Professional Counselors: A Replication Study

The purpose of this investigation was to replicate findings from Holcomb‐McCoy and Myers's ( 1999 ) study, which assessed the multicultural competence of professional counselors. Factor analysis was conducted to determine the components of multicultural competence (N = 171). Differences existed between multicultural competence and race/ethnicity, F(2, 168) = 4.86, p = .009, Wilks's Λ = .95, partial η² = .06, and education level, F(2, 167) = 8.95, p < .001, Wilks's Λ = .82, partial η² = .10.     

HIV status acknowledgment and stigma reduction in virtual reality: The moderating role of perceivers' attitudes

HIV‐related stigmatization in employee selection procedures may be enacted through discrimination based on an applicant's HIV status. This study (N = 58) investigated to what extent applying an acknowledgment strategy in a job interview setting reduces HIV‐related stigma, taking into account the applicants' personal responsibility and the perceivers' attitudes toward people living with HIV (PLWH). In an immersive virtual office, virtual applicants with HIV presented themselves as part of a job application procedure. Using a 2 (acknowledgment versus non‐acknowledgment) × 2 (responsible versus not responsible for the onset of the HIV‐infection) within‐subjects design, we hypothesized that acknowledgment and onset responsibility would yield an interaction effect as well as separate main effects. We predicted that hearing virtual job applicants acknowledging their HIV status triggers higher evaluations, especially when applicants are not held personally responsible for their infection. In addition, we hypothesized that (between‐subjects) positive implicit and explicit attitudes independently moderate the relationship between acknowledgment and applicant evaluation. We found that low‐onset responsible applicants were more positively evaluated than high‐onset responsible applicants (main effect of onset responsibility), F(1, 57) = 4.31, p = 0.04. This effect was irrespective of the applicants' status acknowledgment (no interaction effect). Acknowledgment did, however, produce higher evaluations when participants' explicit attitudes toward PLWH were more positive, F(1, 57) = 7.13, p = 0.01 (moderation effect of explicit attitudes). This study indicates that the more positive the explicit attitudes toward PLWH, the more positive the evaluations when hearing PLWH acknowledging their stigma. Theoretical and practical implications of these findings are discussed.     

The Effects of a Mental Health Video on the Social Skills Knowledge and Attitudes of Mexican Immigrants1

The purpose of this study was to evaluate the effects of a Spanish mental health video, “Cuida Su Salud Mental”, on the relationship attitudes and social skills knowledge of a Mexican immigrant sample. Subjects consisted of 72 Spanish speaking English as a second language (ESL) students recruited from the Paramount Adult School, in the county of Los Angeles. The Solomon (1949) Four Group Design was used. Half of the subjects were pretested on knowledge and attitudes about effective communication skills and relationships, respectively. All subjects view either the mental health video or a control video, and then were posttested on knowledge and attitudes. Results indicated that the mental healthy video (MHV) group exhibited more knowledge, F(1, 62) = 10.61, p= 0.002, and less risky attitudes, F(1, 62) = 4.29, p= 0.043, than the control video group. The MHV group also showed an increase in knowledge from the pretest to the posttest, F(1, 35) = 7.36, p= 0.01. Finally, both video groups reported a decrease in risky attitudes from pretest to posttest, F(1, 34) = 18.21, p= 0.001. These results support the use of “Cuida Su Salud Mental” as a productive and cost-effective mental health intervention that can be used to reach a large segment of the Spanish speaking community.     

音乐训练对大脑前注意加工的影响

前注意加工(pre-attentive processing)是发生在注意之前不依赖于意识的一种认知过程, 它反映了大脑对刺激的无意识的、自动的加工。失匹配负波(mismatch negativity, MMN)是研究前注意加工最常用的指标。MMN波幅降低已成为精神分裂症、抑郁症等精神类疾病的重要临床指征。MMN的研究范式主要包括经典oddball范式和多特征范式等。音乐训练对于人脑结构和功能有重要的影响, 对于增加灰质体积、改善注意记忆功能都有着显著的功效。音乐训练对MMN也有显著影响, 并表现在由各类声音特征构建的范式上。未来研究应进一步比较东西方音乐对MMN的影响, 探索更具生态化效度的研究范式, 揭示音乐训练对老年人MMN的影响及机制。     

How age affects memory task performance in clinically normal hearing persons

The main objective of this study is to investigate memory task performance in different age groups, irrespective of hearing status. Data are collected on a short-term memory task (WAIS-III Digit Span forward) and two working memory tasks (WAIS-III Digit Span backward and the Reading Span Test). The tasks are administered to young (20–30 years, n = 56), middle-aged (50–60 years, n = 47), and older participants (70–80 years, n = 16) with normal hearing thresholds. All participants have passed a cognitive screening task (Montreal Cognitive Assessment (MoCA)). Young participants perform significantly better than middle-aged participants, while middle-aged and older participants perform similarly on the three memory tasks. Our data show that older clinically normal hearing persons perform equally well on the memory tasks as middle-aged persons. However, even under optimal conditions of preserved sensory processing, changes in memory performance occur. Based on our data, these changes set in before middle age.     

Active or Inert? An Experimental Comparison of Creative Ideation across Incubation Periods

The primary objective of this study was to contribute to the growing research discipline investigating the effects of physical exercise on divergent thinking creativity performance. Thirty‐two students participated in this two‐visit, within‐subject intervention. Individuals consented to participate in two randomized, and counterbalanced, experimental conditions, consisting of 15 min of active treadmill walking and an inert, seated control incubation period. Creativity was assessed at baseline and post‐exercise (and control) via the Instances Creativity Task (ICT). Creativity scores for changes in fluency (F(1, 31) = 2.90, p = .10) were not statistically significant across the experimental conditions. Originality scores were higher at baseline and follow‐up when compared to the exercise condition (F(1, 31) = 6.82, p = .01). However, there was no statistically significant condition × time interaction effect (F(1, 31) = 1.78, p = .19). Further analyses demonstrated that there was no statistically significant difference between the experimental conditions on recall score (F(1, 31) = 1.04, p = .32). All models indicated statistically significant main effects for time: fluency (F(1, 31) = 131.17, p < .001); originality (F(1, 31) = 36.54, p < .001); and recall (F(1, 31) = 51.75, p < .001). These findings suggest that both active and inert creative incubation periods may similarly enhance subsequent divergent thinking performance.     

Human central auditory plasticity associated with tone sequence learning

We investigated learning-related changes in amplitude, scalp topography, and source localization of the mismatch negativity (MMN), a neurophysiological response correlated with auditory discrimination ability. Participants (n = 32) underwent two EEG recordings while they watched silent films and ignored auditory stimuli. Stimuli were a standard (probability = 85%) and two deviant (probability = 7.5% each for high [HD] and low [LD]) eight-tone sequences that differed in the frequency of one tone. Between recordings, subjects practiced discriminating the HD or LD from the standard for 6 min. The amplitude of the LD MMN increased significantly across recordings in both groups, whereas the amplitude of the HD MMN did not. The LD was easier to discriminate than was the HD. Thus, practicing either discrimination increased the MMN for the easier discrimination. Learning and changes in the LD MMN amplitude were highly correlated. Source localizations of event-related potentials (ERPs) to all stimuli revealed bilateral sources in superior temporal regions. Compared with the standard ERP, the LD ERP revealed a stronger source in the left superior temporal region in both recordings, whereas the right-sided source became stronger after learning. Consistent with prior studies of auditory plasticity in animals and humans, tone sequence learning induced rapid neurophysiological plasticity in the human central auditory system. The results also suggest that there is asymmetric hemispheric involvement in tone sequence discrimination learning and that discrimination difficulty influences the time course of learning-related neurophysiological changes.