Speech perception in preschoolers at family risk for dyslexia: relations with low-level auditory processing and phonological ability

We tested categorical perception and speech-in-noise perception in a group of five-year-old preschool children genetically at risk for dyslexia, compared to a group of well-matched control children and a group of adults. Both groups of children differed significantly from the adults on all speech measures. Comparing both child groups, the risk group presented a slight but significant deficit in speech-in-noise perception, particularly in the most difficult listening condition. For categorical perception a marginally significant deficit was observed on the discrimination task but not on the identification task. Speech parameters were significantly related to phonological awareness and low-level auditory measures. Results are discussed within the framework of a causal model where low-level auditory problems are hypothesized to result in subtle speech perception problems that might interfere with the development of phonology and reading and spelling ability.     

Working memory impairments in children with specific arithmetic learning difficulties.

Working memory impairments in children with difficulties in arithmetic have previously been investigated using questionable selection techniques and control groups, leading to problems concluding where deficits may occur. The present study attempted to overcome these criticisms by assessing 9-year-old children with difficulties specific to arithmetic, as indicated by normal reading, and comparing them with both age-matched and ability-matched controls. A battery of 10 tasks was used to assess different aspects of working memory, including subtypes of executive function. Relative to age-matched controls, children with poor arithmetic had normal phonological working memory but were impaired on spatial working memory and some aspects of executive processing. Compared to ability-matched controls, they were impaired only on one task designed to assess executive processes for holding and manipulating information in long-term memory. These deficits in executive and spatial aspects of working memory seem likely to be important factors in poor arithmetical attainment.     

The cognitive profile of Chinese children with mathematics difficulties

This study examined how four domain-specific skills (arithmetic procedural skills, number fact retrieval, place value concept, and number sense) and two domain-general processing skills (working memory and processing speed) may account for Chinese children’s mathematics learning difficulties. Children with mathematics difficulties (MD) of two age groups (7-8 and 9-11 years) were compared with age-matched typically achieving children. For both age groups, children with MD performed significantly worse than their age-matched controls on all of the domain-specific and domain-general measures. Further analyses revealed that the MD children with literacy difficulties (MD/RD group) performed the worst on all of the measures, whereas the MD-only group was significantly outperformed by the controls on the four domain-specific measures and verbal working memory. Stepwise discriminant analyses showed that both number fact retrieval and place value concept were significant factors differentiating the MD and non-MD children. To conclude, deficits in domain-specific skills, especially those of number fact retrieval and place value understanding, characterize the profile of Chinese children with MD.     

Phonological storage and executive function deficits in children with mathematics difficulties

Children with mathematics difficulties suffer from working memory deficits. This study investigated the deficit profile of phonological storage and executive functions in working memory among children with mathematics difficulties. Based on multiple instruments and two assessment points, 68 children were screened out of 805 fifth graders. Of these 68 children, 18 were classified as children with only mathematics difficulties (MD), 20 were classified as children with mathematics and reading difficulties (MDRD), and 30 were typically developing (TD) peers matched on age and general ability. Measures for phonological storage, dual-task performance, inhibition, and updating of verbal and numerical materials were administered individually. Results showed that compared with the TD group, children with MD exhibited storage and inhibition deficits specific to numerical information and dual-task deficits of both verbal and numerical information, whereas children with MDRD showed extensive deficits on phonological storage and executive functions on both verbal and numerical tasks. Moreover, executive function deficits were not confined to phonological storage deficits. Implications of the findings for the working memory deficit profile and working memory training among children with mathematics difficulties were discussed.     

Using developmental principles to assist preschoolers in developing numeracy and literacy

In a yoked control design, 4-yr.-olds (N = 39) in a Head Start program played numerous structured games involving either the oddity principle or letter identification and letter sounds. The children's mean age was 53.2 mo.; SD = 4.1 mo. Three were Middle Eastern, 14 were Latino, 7 were East African, and 15 were African American. Children showed better mastery of oddity after playing games directed at this concept, and numeracy scores on the Woodcock-Johnson III were better for children who had played this type of game. Woodcock-Johnson III Letter-Word scores for children who had played the oddity and seriation or letter games were equivalent. These results are consistent with other research indicating that the understanding of oddity relations may be a key transitional thinking which supports quantitative and verbal development at the preschool-kindergarten interface. The standardized test scores indicate that guided play directed at this aspect of cognitive growth or more narrowly directed at early literacy can produce equivalent knowledge of letters.     

Modality-independent impairments in word processing in a deep dyslexic patient

An extensive study of the language abilities of one deep dyslexic patient, B.L., was undertaken. Tests of his ability to comprehend and produce words in the auditory, verbal, and graphic modalities revealed striking similarities in performance across modalities, such that the defining symptoms of deep dyslexic reading also held true for this patient's writing, repetition, and naming. A new dual-deficit model of deep dyslexia is presented which predicts that a variety of “deep dyslexic” syndromes may occur with or without modality-specific impairments.     

Auditory temporal information processing in preschool children at family risk for dyslexia: relations with phonological abilities and developing literacy skills

In this project, the hypothesis of an auditory temporal processing deficit in dyslexia was tested by examining auditory processing in relation to phonological skills in two contrasting groups of five-year-old preschool children, a familial high risk and a familial low risk group. Participants were individually matched for gender, age, non-verbal IQ, school environment, and parental educational level. Psychophysical thresholds were estimated for gap-detection, frequency modulation detection, and tone-in-noise detection using a three-interval forced-choice adaptive staircase paradigm embedded within a computer game. Phonological skills were measured by tasks assessing phonological awareness, rapid serial naming, and verbal short-term memory. Significant group differences were found for phonological awareness and letter knowledge. In contrast, none of the auditory tasks differentiated significantly between both groups. However, both frequency modulation and tone-in-noise detection were significantly related to phonological awareness. This relation with phonological skills was not present for gap-detection.     

False memories in individuals at risk for developing an eating disorder

In the present study, the authors used the Roediger and McDermott paradigm (H. L. Roediger & K. B. McDermott, 1995) to examine the creation of false memories in individuals at risk for developing an eating disorder. Thirty-three controls and 34 individuals at risk for eating disorders studied 6 word lists taken from the paradigm. Three lists were food related (bread, fruit, sweet), and 3 were not food related (king, doctor, black). Both groups produced false memories (i.e., recalled or recollected words that were not presented in the lists), and controls actually produced more false memories than the at-risk individuals produced in the recall of the food-related items. Groups did not differ in their recall of items not related to food.     

Biased processing of emotional information in girls at risk for depression

Researchers have documented that children of depressed mothers are at elevated risk for developing a depressive disorder themselves. There is currently little understanding, however, of what factors place these children at elevated risk. In the present study, the authors investigated whether never-disordered daughters whose mothers have experienced recurrent episodes of depression during their daughters' lifetime are characterized by biased processing of emotional information. Following a negative mood induction, participants completed an emotional-faces dot-probe task. Daughters at elevated risk for depression, but not control daughters of never-disordered mothers, selectively attended to negative facial expressions. In contrast, only control daughters selectively attended to positive facial expressions. These results provide support for cognitive vulnerability models of depression.     

The role of inhibition and speed of processing in mathematics

The current study highlights the importance of inhibitory ability in facilitating performance in mathematics. To understand the role of inhibition in mathematical knowledge, this study tested 102 college students on a series of standardized complex math exercises. Inhibition tasks varied by task and stimuli (letters, numbers, and arrows). The result showed stronger associations between math abilities and strength of inhibition with more inhibition found for the flanker task (involving inhibition of peripheral stimuli) than for the Navon task (requiring inhibition of a potential response). The results supported the view that Inhibition in general (which is not unique to numerical stimuli) is associated with math abilities. General, rather than specific inhibition was associated with math abilities and finally, speed of processing masked the relationship between math and inhibition. These results confirm the assumption that the relation between inhibition and math performance is modulated by the task that measures the inhibition, and by additional predictors such as processing speed.     

The development of automatic numerosity processing in preschoolers: evidence for numerosity-perceptual interference

Three experiments examined developmental changes in the automatic processing of numerosity and perceptual information using a nonsymbolic numerical Stroop paradigm. In Experiments 1 and 2 (E1 and E2), 4-, 5-, and 6-year-olds had to compare the numerosities or the total filled areas of collections of dots (E1) or bars (E2) varying along both dimensions. Experiment 3 replicated E2's results in 3-, 4-, and 5-year-olds. Results demonstrated the existence of reciprocal influences between numerical and perceptual information beginning at age 3. Moreover, the irrelevant perceptual influences remained stable throughout development, whereas the sensitivity to irrelevant numerical cues tended to increase with age despite children's growing inhibition capacities. No significant correlation could be found between these developmental changes and the acquisition of counting knowledge.     

Aberrant semantic and affective processing in people at risk for psychosis

Semantic and affective processing were examined in people at risk for psychosis. The participants were 3 groups of college students: 41 people with elevated Perceptual Aberration and Magical Ideation (PerMag) scores, 18 people with elevated Social Anhedonia (SocAnh) scores, and 100 control participants. Participants completed a single-word, continuous presentation pronunciation task that included semantically related words, affectively valenced words, and semantically unrelated and affectively neutral words. PerMag participants exhibited increased semantic priming and increased sensitivity to affectively valenced primes. SocAnh participants had increased sensitivity to affectively valenced targets.     

Processing fat-related information in individuals at risk for developing an eating disorder

The authors examined the effect that being at risk for developing an eating disorder has on the lexical processing of words related to fat and words not related to fat. Individuals (n = 17) at risk for developing an eating disorder were compared with controls (n = 31) using a lexical decision task in which fat-related words (e.g., large), unrelated words (e.g., fair), neutral words (e.g., post), and pseudowords (e.g., flirp) were given. The results revealed an expected Group x Stimuli interaction for reaction times indicating that at-risk individuals were significantly faster at processing fat-related words than words unrelated to fat. The authors discuss these results within the context of how fat-related stimuli are processed in at-risk individuals and how models of information processing can aid in the interpretation and understanding of eating disorders.     

Identifying the nature of impairments in executive functioning and working memory of children with severe difficulties in arithmetic

An age-matched achievement-matched design was used to examine whether the executive functioning and working memory impairments exhibited by children with severe difficulties in arithmetic (SDA) are better viewed as developmental lags or as cognitive deficits. Three groups of children were included: 20 SDA children, 20 typically achieving children (CM) matched in chronological age with the SDA children, and 20 younger typically achieving children (AM) matched in achievement with the SDA group. While children with SDA did not exhibit impairments in color-word inhibition and verbal working memory, they did demonstrate impairments in shifting, quantity-digits inhibition, and visuospatial working memory. As children with SDA did not perform more poorly than their AM counterparts on any of these tasks, impairments in specific areas of executive functioning and working memory appear to reflect developmental lags rather than cognitive deficits.     

ANS acuity and mathematics ability in preschoolers from low‐income homes: contributions of inhibitory control

Recent findings by Libertus, Feigenson, and Halberda (2011) suggest that there is an association between the acuity of young children's approximate number system (ANS) and their mathematics ability before exposure to instruction in formal schooling. The present study examined the generalizability and validity of these findings in a sample of preschoolers from low‐income homes. Children attending Head Start (N = 103) completed measures to assess ANS acuity, mathematics ability, receptive vocabulary, and inhibitory control. Results showed only a weak association between ANS acuity and mathematics ability that was reduced to non‐significance when controlling for a direct measure of receptive vocabulary. Results also revealed that inhibitory control plays an important role in the relation between ANS acuity and mathematics ability. Specifically, ANS acuity accounted for significant variance in mathematics ability over and above receptive vocabulary, but only for ANS acuity trials in which surface area conflicted with numerosity. Moreover, this association became non‐significant when controlling for inhibitory control. These results suggest that early mathematical experiences prior to formal schooling may influence the strength of the association between ANS acuity and mathematics ability and that inhibitory control may drive that association in young children.     

Effective brain connectivity in children with reading difficulties during phonological processing

Using Dynamic Causal Modeling (DCM) and functional magnetic resonance imaging (fMRI), we examined effective connectivity between three left hemisphere brain regions (inferior frontal gyrus, inferior parietal lobule, fusiform gyrus) and bilateral medial frontal gyrus in 12 children with reading difficulties (M age=12.4, range: 8.11-14.10) and 12 control children (M age=12.3, range: 8.9-14.11) during rhyming judgments to visually presented words. More difficult conflicting trials either had similar orthography but different phonology (e.g. pint-mint) or similar phonology but different orthography (e.g. jazz-has). Easier non-conflicting trials had similar orthography and phonology (e.g. dime-lime) or different orthography and phonology (e.g. staff-gain). The modulatory effect from left fusiform gyrus to left inferior parietal lobule was stronger in controls than in children with reading difficulties only for conflicting trials. Modulatory effects from left fusiform gyrus and left inferior parietal lobule to left inferior frontal gyrus were stronger for conflicting trials than for non-conflicting trials only in control children but not in children with reading difficulties. Modulatory effects from left inferior frontal gyrus to inferior parietal lobule, from medial frontal gyrus to left inferior parietal lobule, and from left inferior parietal lobule to medial frontal gyrus were positively correlated with reading skill only in control children. These findings suggest that children with reading difficulties have deficits in integrating orthography and phonology utilizing left inferior parietal lobule, and in engaging phonological rehearsal/segmentation utilizing left inferior frontal gyrus possibly through the indirect pathway connecting posterior to anterior language processing regions, especially when the orthographic and phonological information is conflicting.     

Cognitive processing impairments in a supra-second temporal discrimination task in rats with cerebellar lesion

The role of interpositus nuclei (IN) in timing in the sub-second range is well supported in eyeblink conditioning studies. Timing impairments shown in the seconds range in patients with intermediate cerebellar lesion, and known intermediate cerebellar cortex projection to IN raise the question of a possible involvement of IN in timing in the supra-second range as well. To address this question, we tested rats (Sprague-Dawley) given bilateral lesions of IN with Colchicine in a 2- vs. 8-s temporal discrimination task, followed by three daily sessions of a temporal bisection tests with five added intermediate non-reinforced durations. IN lesioned rats showed normal acquisition of the temporal discrimination, but a transient impairment of temporal sensitivity during the bisection tests. In addition, their response latencies suggested a different behavioral strategy from that of control animals. Our results indicate that the IN of the cerebellum may not be critically involved in temporal processing in the 2–8 s range, but may play a role in the cognitive processes that access temporal information in the mediation of choice behavior.     

Verbal ability and executive functioning development in preschoolers at head start

Research suggests that executive functioning skills may enhance the school readiness of children from disadvantaged homes. Questions remain, however, concerning both the structure and the stability of executive functioning among preschoolers. In addition, there is a lack of research addressing potential predictors of longitudinal change in executive functioning during early childhood. This study examined the structure of executive functioning from fall to spring of the preschool year using a multimethod battery of measures. Confirmatory factor analyses revealed a unidimensional model fit the data well at both time points, and tests of measurement invariance across time points indicated that children's mean latent executive functioning scores significantly improved over time. Verbal ability was a significant predictor of longitudinal change in executive functioning. Theoretical implications and directions for future research are discussed.     

The effect of mathematics anxiety on the processing of numerical magnitude

In an effort to understand the origins of mathematics anxiety, we investigated the processing of symbolic magnitude by high mathematics-anxious (HMA) and low mathematics-anxious (LMA) individuals by examining their performance on two variants of the symbolic numerical comparison task. In two experiments, a numerical distance by mathematics anxiety (MA) interaction was obtained, demonstrating that the effect of numerical distance on response times was larger for HMA than for LMA individuals. These data support the claim that HMA individuals have less precise representations of numerical magnitude than their LMA peers, suggesting that MA is associated with low-level numerical deficits that compromise the development of higher level mathematical skills.