Childhood depression: Peer reactions to depression and life stress

The present study investigated children's responses to a peer's childhood depression. Younger children in third and fourth grade and older children in fifth and sixth grade were exposed to one of four films. The four films portrayed a female peer who was either depressed or not depressed and who had experienced numerous recent life stresses or no recent life stress. Overall, children rated the depressed peers as less likable and attractive, as engaging in fewer positive current and future behaviors, and as needing therapy more than a nondepressed peer. There was a tendency to rate the depressed peer with high life stress more positively than the depressed peer with low life stress; this tendency decreased with age. Girls rated all of the peers and especially the stressed peers more positively than did the boys. The results are discussed in terms of the implications of children's social interaction for the initiation or maintenance of childhood depression.The authors would like to thank Kelly Merk and Susan Vanderheid for their assistance with this research.     

同伴对青少年冒险行为的影响及其作用机制

青少年更倾向于从事冒险或鲁莽行为, 并且更容易受到同伴影响。从个人特质和社交互动等多个角度探讨的研究结果表明, 同伴对青少年冒险行为存在助长作用, 即当同伴在场时, 青少年的行为会更加冒险。同伴对青少年冒险行为的作用机制可以从心理、神经、遗传、社会文化等多个层面进行解释：在心理层面, 这种影响源于青少年寻求同伴认可和归属感的需要, 以及社会学习的作用; 在神经机制层面, 源于认知控制网络和刺激处理系统的相互作用; 在遗传层面, 源于特定基因的易感性等; 在社会文化层面, 同伴影响会因文化差异而带来程度与表现上的差异。未来研究应从发展、文化心理、构建复杂模型网络等视角深入探究同伴对青少年冒险行为的影响。     

Impaired Neurocognitive Functions Affect Social Learning Processes in Oppositional Defiant Disorder and Conduct Disorder: Implications for Interventions

In this review, a conceptualization of oppositional defiant (ODD) and conduct disorder (CD) is presented according to which social learning processes in these disorders are affected by neurocognitive dysfunctions. Neurobiological studies in ODD and CD suggest that the ability to make associations between behaviors and negative and positive consequences is compromised in children and adolescents with these disorders due to reduced sensitivity to punishment and to reward. As a result, both learning of appropriate behavior and learning to refrain from inappropriate behavior may be affected. Likewise, problem solving is impaired due to deficiencies in inhibition, attention, cognitive flexibility, and decision making. Consequently, children and adolescents with ODD and CD may have difficulty learning to optimize their behavior in changeable environments. This conceptualization of ODD and CD is relevant for the improvement of the effect of psychological treatments. Behavioral and cognitive-behavioral interventions that have been shown to be modestly effective in ODD and CD are based on social learning. Limited effectiveness of these interventions may be caused by difficulties in social learning in children and adolescents with ODD and CD. However, although these impairments have been observed at a group level, the deficits in reward processing, punishment processing, and cognitive control mentioned above may not be present to the same extent in each individual with ODD and CD. Therefore, the neurocognitive characteristics in children and adolescents with ODD and CD should be assessed individually. Thus, instead of delivering interventions in a standardized way, these programs may benefit from an individualized approach that depends on the weaknesses and strengths of the neurocognitive characteristics of the child and the adolescent.     

Linking family structure to impulse‐control and obsessive–compulsive buying

Compulsive buying affects the well‐being of millions of consumers globally by resulting in depression, unmanageable debt, and lower satisfaction with life. This research examines the mechanisms that link aversive family events experienced in childhood to compulsive buying tendencies in early adulthood. The article develops a set of hypotheses derived from the main theoretical perspectives of the multi‐theoretical life course paradigm, and it uses a sample of 492 young adults to test them. The results suggest that social processes are the underlying mechanisms that promote the development of compulsive buying tendencies. Family disruptions reduce intangible family resources that then shape the nature of interactions with peers and parents. Peer communications in formative years are directly linked to both obsessive–compulsive and impulse‐control dimensions of compulsive buying in early adulthood. The study findings help interpret and integrate previous research streams on compulsive buying from different fields of social sciences. Implications of the findings are offered along with directions for further research. Copyright © 2016 John Wiley & Sons, Ltd.     

Grief and Attitudes Toward Suicide in Peers Affected by a Cluster of Suicides as Adolescents

Eighty‐five young adults exposed to a cluster of peer suicides as adolescents completed measures of attitudes toward suicide, grief, and social support. Closeness to the peers lost to suicide was positively correlated with grief and the belief that suicide is not preventable, with grief further elevated in close individuals with high social support from friends. Overall, social support was related to healthy attitudes about suicide including preventability, yet it was also related to some stigmatizing beliefs. Compared with 67 young adults who had not been exposed to a suicide cluster, the exposed sample was more likely to think that suicide is normal but more likely to think of it as incomprehensible.     

Simultaneous and independent acquisition of multisensory and unisensory associations

Although humans are almost constantly exposed to stimuli from multiple sensory modalities during daily life, the processes by which we learn to integrate information from multiple senses to acquire knowledge of multisensory objects are not well understood. Here, we present results of a novel audio-visual statistical learning procedure where participants are passively exposed to a rapid serial presentation of arbitrary audio-visual pairings (comprised of artificial/ synthetic audio and visual stimuli). Following this exposure, participants were tested with a two-interval forced-choice procedure in which their degree of familiarity with the experienced audio-visual pairings was evaluated against novel audio-visual combinations drawn from the same stimulus set. Our results show that subjects acquire knowledge of visual-visual, audio-audio, and audio-visual stimulus associations and that the learning of these types of associations occurs in an independent manner.     

Effects of early sensorimotor disorder on contextual learning in autism

Cognitive explanations of autism often involve higher order cognitive functions developing late in childhood, such as theory of mind, executive functions or central coherence. In home videos of infants later diagnosed with autism, children display early signs of developmental disorders, for example impaired sensorimotor functions, attention to social and non-social stimuli and a lack of circadian regulation. We propose that these early signs need to be understood using a framework of context learning. It is also important to understand the role for context understanding in guiding the maturation of behavior. The role for inhibition in context learning as understood within learning theory provides us with helpful tools for this analysis. Our research aim is not to identify and explain early markers for autism, but to understand the cognitive developmental pathway set into rolling by an early impairment. This will help us understand the seemingly unrelated symptoms that define the complex syndrome of autism.     

Cognitive control deployment is flexibly modulated by social value in early adolescence

Recent mechanistic models of cognitive control define the normative level of control deployment as a function of the effort cost of exerting control balanced against the reward that can be attained by exerting control. Despite these models explaining empirical findings in adults, prior literature has suggested that adolescents may not adaptively integrate value into estimates of how much cognitive control they should deploy. Moreover, much work in adolescent neurodevelopment casts social valuation processes as competing with, and in many cases overwhelming, cognitive control in adolescence. Here, we test whether social incentives can adaptively increase cognitive control. Adolescents (M_age = 14.64, 44 male, N = 87) completed an incentivized cognitive control task in which they could exert cognitive control to receive rewards on behalf of real peers who were rated by all peers in their school grade as being of either high- or low-status. Using Bayesian modeling, we find robust evidence that adolescents exert more cognitive control for high- relative to low-status peers. Moreover, we demonstrate that social incentives, irrespective of their high- or low-status, boost adolescent cognitive control above baseline control where no incentives are offered. Findings support the hypothesis that the cognitive control system in early adolescence is flexibly modulated by social value.     

The reciprocal relation between sleep and memory in infancy: Memory‐dependent adjustment of sleep spindles and spindle‐dependent improvement of memories

Sleep spindle activity in infants supports their formation of generalized memories during sleep, indicating that specific sleep processes affect the consolidation of memories early in life. Characteristics of sleep spindles depend on the infant's developmental state and are known to be associated with trait‐like factors such as intelligence. It is, however, largely unknown which state‐like factors affect sleep spindles in infancy. By varying infants’ wake experience in a within‐subject design, here we provide evidence for a learning‐ and memory‐dependent modulation of infant spindle activity. In a lexical‐semantic learning session before a nap, 14‐ to 16‐month‐old infants were exposed to unknown words as labels for exemplars of unknown object categories. In a memory test on the next day, generalization to novel category exemplars was tested. In a nonlearning control session preceding a nap on another day, the same infants heard known words as labels for exemplars of already known categories. Central–parietal fast sleep spindles increased after the encoding of unknown object–word pairings compared to known pairings, evidencing that an infant's spindle activity varies depending on its prior knowledge for newly encoded information. Correlations suggest that enhanced spindle activity was particularly triggered, when similar unknown pairings were not generalized immediately during encoding. The spindle increase triggered by previously not generalized object–word pairings, moreover, boosted the formation of generalized memories for these pairings. Overall, the results provide first evidence for a fine‐tuned regulation of infant sleep quality according to current consolidation requirements, which improves the infant long‐term memory for new experiences.     

Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms

Among people exposed to major psychological stressors in early life, there are elevated rates of morbidity and mortality from chronic diseases of aging. The most compelling data come from studies of children raised in poverty or maltreated by their parents, who show heightened vulnerability to vascular disease, autoimmune disorders, and premature mortality. These findings raise challenging theoretical questions. How does childhood stress get under the skin, at the molecular level, to affect risk for later diseases? And how does it incubate there, giving rise to diseases several decades later? Here we present a biological embedding model, which attempts to address these questions by synthesizing knowledge across several behavioral and biomedical literatures. This model maintains that childhood stress gets "programmed" into macrophages through epigenetic markings, posttranslational modifications, and tissue remodeling. As a consequence these cells are endowed with proinflammatory tendencies, manifest in exaggerated cytokine responses to challenge and decreased sensitivity to inhibitory hormonal signals. The model goes on to propose that over the life course, these proinflammatory tendencies are exacerbated by behavioral proclivities and hormonal dysregulation, themselves the products of exposure to early stress. Behaviorally, the model posits that childhood stress gives rise to excessive threat vigilance, mistrust of others, poor social relationships, impaired self-regulation, and unhealthy lifestyle choices. Hormonally, early stress confers altered patterns of endocrine and autonomic discharge. This milieu amplifies the proinflammatory environment already instantiated by macrophages. Acting in concert with other exposures and genetic liabilities, the resulting inflammation drives forward pathogenic mechanisms that ultimately foster chronic disease.     

Changes in Neuroticism Following Trauma Exposure

Using longitudinal data, the present study examined change in midlife neuroticism following trauma exposure. Our primary analyses included 670 participants (M_age = 60.55; 65.22% male, 99.70% Caucasian) who completed the NEO Personality Inventory at ages 42 and 50 and reported their lifetime exposure to traumatic events approximately 10 years later. No differences in pre‐ and post‐trauma neuroticism scores were found among individuals who experienced all of their lifetime traumas in the interval between the personality assessments. Results were instead consistent with normative age‐related declines in neuroticism throughout adulthood. Furthermore, longitudinal changes in neuroticism scores did not differ between individuals with and without histories of midlife trauma exposure. Examination of change in neuroticism following life‐threatening traumas yielded a comparable pattern of results. Analysis of facet‐level scores largely replicated findings from the domain scores. Overall, our findings suggest that neuroticism does not reliably change following exposure to traumatic events in middle adulthood. Supplemental analyses indicated that individuals exposed to life‐threatening traumas in childhood or adolescence reported higher midlife neuroticism than individuals who experienced severe traumas in adulthood. Life‐threatening traumatic events encountered early in life may have a more pronounced impact on adulthood personality than recent traumatic events.     

The juvenile transition: A developmental switch point in human life history

This paper presents a new perspective on the transition from early to middle childhood (i.e., human juvenility), investigated in an integrative evolutionary framework. Juvenility is a crucial life history stage, when social learning and interaction with peers become central developmental functions; here it is argued that the “juvenile transition” is a developmental switch point in the human life history, when both sex-related and individual differences in reproductive strategies are expressed after the assessment period provided by early childhood. Adrenarche, the secretion of adrenal androgens starting at the beginning of middle childhood, is proposed as the endocrine mechanism mediating the juvenile transition. It is argued that, in connection with the stress system, adrenal androgens enable adaptive plasticity in the development of reproductive strategies through integration of environmental and genetic factors. Finally, evidence is reviewed of both sex-related and individual differences arising during the juvenile transition, in the domains of attachment and aggression. Juvenility plays a central role in the ontogeny of behavior and personality; this paper contributes to defining its place within an integrated model of human development.     

The Indirect Effects of Social Network Characteristics and Normative Beliefs in the Association between Adolescent Depressive Symptomatology and Binge Drinking

Adolescents who experience depression have different attributional styles and may overestimate how much alcohol their friends consume. This misperception may increase binge drinking among adolescents with depressive symptomatology. The social networks of adolescents with depressive symptomatology are systematically different, providing different social learning opportunities. Using Add Health, we find that individuals who suffer from depressive symptomatology are more likely to have peers with higher depression scores. Adolescents with higher depressive symptomatology are more likely to perceive their peers as drinking alcohol. Our results suggest that normative beliefs are the key mediator in explaining the association between depressive symptomatology and binge drinking.     

Electrophysiological correlates of observational learning in children

Observational learning is an important mechanism for cognitive and social development. However, the neurophysiological mechanisms underlying observational learning in children are not well understood. In this study, we used a probabilistic reward‐based observational learning paradigm to compare behavioral and electrophysiological markers of individual and observational reinforcement learning in 8‐ to 10‐year‐old children. Specifically, we manipulated the amount of observable information as well as children's similarity in age to the observed person (same‐aged child vs. adult) to examine the effects of similarity in age on the integration of observed information in children. We show that the feedback‐related negativity (FRN) during individual reinforcement learning reflects the valence of outcomes of own actions. Furthermore, we found that the feedback‐related negativity during observational reinforcement learning (oFRN) showed a similar distinction between outcome valences of observed actions. This suggests that the oFRN can serve as a measure of observational learning in middle childhood. Moreover, during observational learning children profited from the additional social information and imitated the choices of their own peers more than those of adults, indicating that children have a tendency to conform more with similar others (e.g. their own peers) compared to dissimilar others (adults). Taken together, our results show that children can benefit from integrating observable information and that oFRN may serve as a measure of observational learning in children.     

Life‐events and post‐traumatic stress in a sample of English adolescents

The aim of the present study was to investigate the lifetime prevalence of negative life‐events and their association with post‐traumatic stress in English adolescents. Of the 427 adolescents surveyed, 360 (84%) endorsed at least one negative event. Respondents were asked to complete the Impact of Event Scale (IES: Horowitz, Wilner and Alvarez, 1979) for each event that they endorsed. For boys, highest levels of post‐traumatic stress were found in those who had experience of a ‘family member with a drink or drugs problem’, followed by ‘parental separation or divorce’, ‘life threat to family member’, and ‘life‐threat to self ’. For girls, highest levels of post‐traumatic stress were found in those who had experienced ‘attack or physical assault to self ’, followed by ‘family member with drink or drugs problem’, ‘parental separation or divorce’, and ‘life threat to family member’. These data suggest that moderate levels of post‐traumatic stress are present in around one fifth of adolescents who have experienced one of these events and that community levels of post‐traumatic stress in adolescents may be higher than previously thought. Copyright © 2000 John Wiley & Sons, Ltd.     

The effect of perceived parental involvement and the use of growth-fostering relationships on self-concept in adolescents participating in gear up

Adolescence is marked by physical, cognitive, and social changes which affect how individuals perceive themselves. However, individuals do integrate their perceptions with those of significant others. Adolescents' self-concept is influenced by their relationships with family, peers, mentors, and community groups. In this study, the characteristics of these relationships are examined as well as the perception of parental involvement. The effect of perceived parental involvement and the use of growth-fostering relationships on self-concept was examined using 78 adolescents who were participating in GEAR UP (Gaining Early Awareness of Readiness for Undergraduate Programs). Results support the influence of family, peers, mentors, and involvement in community groups on adolescent self-concept.     

The effect of early life stress on the cognitive phenotype of children with an extra X chromosome (47,XXY/47,XXX)

Studies on gene–environment interactions suggest that some individuals may be more susceptible to life adversities than others due to their genetic profile. This study assesses whether or not children with an extra X chromosome are more vulnerable to the negative impact of early life stress on cognitive functioning than typically-developing children.

A total of 50 children with an extra X chromosome and 103 non-clinical controls aged 9 to 18 years participated in the study. Cognitive functioning in domains of language, social cognition and executive functioning were assessed. Early life stress was measured with the Questionnaire of Life Events. High levels of early life stress were found to be associated with compromised executive functioning in the areas of mental flexibility and inhibitory control, irrespective of group membership. In contrast, the children with an extra X chromosome were found to be disproportionally vulnerable to deficits in social cognition on top of executive dysfunction, as compared to typically-developing children. Within the extra X group the number of negative life events is significantly correlated with more problems in inhibition, mental flexibility and social cognition. It is concluded that children with an extra X chromosome are vulnerable to adverse life events, with social cognition being particularly impacted in addition to the negative effects on executive functioning. The findings that developmental outcome is codependent on early environmental factors in genetically vulnerable children also underscores opportunities for training and support to positively influence the course of development.     

Social Cognition and Interpersonal Impairment in Young Adolescents with ADHD

The purpose of this study is twofold. First, it aims to examine whether the impairment in peer functioning and social-cognitive deficits (i.e., hostile attribution bias, social comprehension, social problem-solving) found in elementary school aged children with ADHD also occur in adolescence. Second, it aims to provide evidence for a predictive relationship between these social-cognitive deficits and an adolescent’s functional impairment in the social domain. To address these aims, several social-cognitive tasks were administered to a small sample of young adolescents with ADHD (N = 27) and a comparison sample without an ADHD diagnosis (N = 18). Parent report of functional impairment and peer sociometric data were also gathered. Comparisons of both parent and peer report of adolescent social functioning suggest that individuals with ADHD continue to experience difficulties with peers into the adolescent years and data from the social-cognitive tasks show evidence of social comprehension and problem-solving deficits. Further analyses indicated a significant link between functional impairment and social cognition. Findings herein are discussed in the context of both the developmental changes that arise during adolescence and consideration of the importance of social cognition for understanding the impaired social functioning experienced by adolescents with ADHD.     

The role of general cognitive ability in moderating the relation of adverse life events to emotional and behavioural problems

Previous studies have established the role of various measures of cognitive functioning in dampening the association between adverse life events (‘life stress’) and adolescents’ emotional and behavioural problems. However, it is not yet clear if general cognitive ability (‘intelligence’) is a protective factor. In this study of 1,175 10‐ to 19‐year‐olds in five secondary schools in England, we explored this issue. We found that even after controlling for sex, age, family poverty, and special educational needs, the association of life stress with emotional, hyperactivity, and conduct problems was significant. General cognitive ability moderated the association between life stress and conduct problems; among adolescents with higher than average general cognitive ability, the association between life stress and conduct problems was non‐significant.     

Adolescent-specific patterns of behavior and neural activity during social reinforcement learning

Humans are sophisticated social beings. Social cues from others are exceptionally salient, particularly during adolescence. Understanding how adolescents interpret and learn from variable social signals can provide insight into the observed shift in social sensitivity during this period. The present study tested 120 participants between the ages of 8 and 25 years on a social reinforcement learning task where the probability of receiving positive social feedback was parametrically manipulated. Seventy-eight of these participants completed the task during fMRI scanning. Modeling trial-by-trial learning, children and adults showed higher positive learning rates than did adolescents, suggesting that adolescents demonstrated less differentiation in their reaction times for peers who provided more positive feedback. Forming expectations about receiving positive social reinforcement correlated with neural activity within the medial prefrontal cortex and ventral striatum across age. Adolescents, unlike children and adults, showed greater insular activity during positive prediction error learning and increased activity in the supplementary motor cortex and the putamen when receiving positive social feedback regardless of the expected outcome, suggesting that peer approval may motivate adolescents toward action. While different amounts of positive social reinforcement enhanced learning in children and adults, all positive social reinforcement equally motivated adolescents. Together, these findings indicate that sensitivity to peer approval during adolescence goes beyond simple reinforcement theory accounts and suggest possible explanations for how peers may motivate adolescent behavior.