Neuroimaging of multisensory processing in vision,audition, touch,and olfaction

The development of neuroimaging methods has had a significant impact on the study of the human brain. Functional MRI, with its high spatial resolution, provides investigators with a method to localize the neuronal correlates of many sensory and cognitive processes. Magneto- and electroencephalography, in turn, offer excellent temporal resolution allowing the exact time course of neuronal processes to be investigated. Applying these methods to multisensory processing, many research laboratories have been successful in describing cross-sensory interactions and their spatio-temporal dynamics in the human brain. Here, we review data from selected neuroimaging investigations showing how vision can influence and interact with other senses, namely audition, touch, and olfaction. We highlight some of the similarities and differences in the cross-processing of the different sensory modalities and discuss how different neuroimaging methods can be applied to answer specific questions about multisensory processing.Edited by: Marie-Hélène Giard and Mark Wallace     

Psychodynamics of Suicide in Lesbian,Gay, Bisexual,or Transgender Youth

Lesbian, gay, bisexual, and transgender (LGBT) youth are a vulnerable population at high risk of suicide and, as such, benefit from an informed psychotherapeutic approach to treatment. While it is clear that sexual orientation and gender identity are independent dimensions from psychopathology, LGBT youth are frequently marginalized and may face unique challenges with self-acceptance and identification with peers, family, and society, increasing risk of social isolation, which in turn increases vulnerability to anxiety, mood disorders, substance use, and suicide. We elaborate on the common phenomenon of ambivalent repression of the sexual self in adolescents associated with intertwined themes frequently expressed in suicidal lesbian, gay, transgender, bisexual, and queer patients on the inpatient adolescent unit: anger directed toward internal and external objects; desire for self-punishment, atonement, and possibly rebirth; and desperation and desire to escape psychic pain. We enhance our discussion with case examples and practical therapeutic considerations that emerge from these themes that can be harnessed across treatment settings.     

Definitions of Idioms in Preadolescents, Adolescents, and Adults

The purpose of this study was to expand the current literature on word definitions by focusing on definitions of idioms provided by several age groups. Preadolescents, young adolescents, older adolescents, and adults wrote definitions for 10 frequently used idioms and also rated their familiarity with the idiomatic expressions. Participants’ definitions were scored based on the degree to which their definitions reflected use of critical elements (determined by a standard dictionary of idioms), use of examples or related/associated concepts, and errors. Significant age differences were found in both idiom familiarity and idiom definition tasks: both idiom familiarity and definitional skill improved with age. In addition, we found a positive correlation between idiom familiarity and idiom definition. Results are discussed with respect to age-related changes in definitional response types and understanding of figurative language.     

Characterization of state transitions in spatially distributed,chaotic, nonlinear,dynamical systems in cerebral cortex

The neurons of cerebral cortex are largely autonomous and generate activity that is manifested in trains of microscopic axonal action potentials. The neurons interact by sparse but numerous synaptic connections to generate macroscopic dendritic activity patterns that are observed in electroencephalographic (EEG) waves. The macroscopic patterns are constructed by the populations and they shape the output of cortical neurons in parallel arrays. Sensory cortexes receive sensory information in the form of microscopic action potentials, which induce state transitions in population dynamics. Each state transition transforms sensory information to perceptual meaning. The EEG reflects both kinds of activity. The sensory input is accessed by time ensemble averaging, whereas the perceptual output is found by spatial ensemble averaging. Spatial phase gradients in the EEG are useful for identifying EEG segments in a sequence of state transitions in response to sensory input. The rapidity and flexibility with which they take place give strong reason to postulate that the mechanism for the construction of these sequences of patterns is a dynamical system operating in a chaotic domain.     

Factor analysis of the heterosexist harassment,rejection, and discrimination scale in lesbian,gay, bisexual,transgender, and queer people of colour

The factor structure of the Heterosexist Harassment, Rejection, and Discrimination Scale (HHRDS) was examined in lesbian, gay, bisexual, transgender, and queer (LGBTQ) people of colour. Two hundred participants completed a survey with the HHRDS and several mental health scales. A confirmatory factor analysis suggested the original HHRDS structure fit the data poorly. Exploratory factor analyses found a different 2-factor structure, consisting of harassment/rejection and family discrimination. Convergent validity analyses demonstrated that family discrimination had the largest association with depression and anxiety, indicating that family discrimination may be particularly salient among LGBTQ people of colour. This study supports the use of the HHRDS in racially/ethnically diverse samples, but with a slightly different factor structure. Examining discriminatory experiences from family members is an important direction for future research in LGBTQ people of colour.     

Matching, undermatching, and overmatching in studies of choice

Almost all of 103 sets of data from 23 different studies of choice conformed closely to the equation: log (B(1)/B(2)) = a log (r(1)/r(2)) + log b, where B(1) and B(2) are either numbers of responses or times spent at Alternatives 1 and 2, r(1) and r(2) are the rates of reinforcement obtained from Alternatives 1 and 2, and a and b are empirical constants. Although the matching relation requires the slope a to equal 1.0, the best-fitting values of a frequently deviated from this. For B(1) and B(2) measured as numbers of responses, a tended to fall short of 1.0 (undermatching). For B(1) and B(2) measured as times, a fell to both sides of 1.0, with the largest mode at about 1.0. Those experiments that produced values of a for both responses and time revealed only a rough correspondence between the two values; a was often noticeably larger for time. Statistical techniques for assessing significance of a deviation of a from 1.0 suggested that values of a between .90 and 1.11 can be considered good approximations to matching. Of the two experimenters who contributed the most data, one generally found undermatching, while the other generally found matching. The difference in results probably arises from differences in procedure. The procedural variations that lead to undermatching appear to be those that produce (a) asymmetrical pausing that favors the poorer alternative; (b) systematic temporal variation in preference that favors the poorer alternative; and (c) patterns of responding that involve changing over between alternatives or brief bouts at the alternatives.     

神经颗粒素与脑老化、疾病及应激关系

神经颗粒素是一种神经元特异性、Ca2＋敏感性的鈣调蛋白（CaM）结合蛋白,是蛋白激酶C的突触后底物,与信号传导和长时程增强（LTP）有关。这是一种新发现的脑特异性蛋白质。主要分布在前脑和海马,在皮质、海马CA1-CA3区、齿状回、纹状体和杏仁核中高表达。在大脑发育的不同阶段,神经颗粒素在脑内的含量和分布区域会发生变化,其生物学作用受到国内外学者的关注。近年来国外学者开始对神经颗粒素与脑老化、疾病及应激关系进行考查。该文将着重介绍对神经颗粒素在脑老化、疾病和应激过程中所扮演的角色的研究工作及其新发现,目的是对脑与行为关系的理解及有关的脑机制的研究提供一个新的视点。     

Religion,sexuality, and (in)equality in the lives of older lesbian,gay, and bisexual people in the United Kingdom

This article explores how older lesbian, gay, and bisexual (LGB) people in the United Kingdom engage with religion in later life. Drawing on research with older persons who are LGB and with activists, it explores religious spaces as sites of both inclusion and exclusion, historically and in the present day. Particular consideration is given to the equality implications, in the form of parity of participation, including in the context of religious-based social care provision for older people. Future research implications are addressed.     

Attitudes to,and habits of,gambling in Britain

This study aimed to investigate the relationship between demographic (e.g. age, sex) psychological belief (e.g. alienation, conservatism) and attitudes towards, and habits of, gambling. Over 250 people from a variety of backgrounds completed a number of standardized questionnaires. A factor analysis of the Attitude to Gambling scale revealed five clearly interpretable factors which were computed into subscale scores and related to the independent variables. A canonical correlation showed that age and alienation were most closely related to gambling attitudes. Analysis of the Gambling Habits scale showed that sex, age and education best discriminated the Ss' habits of gambling. A correlational analysis between attitudes and habits yielded some interesting and predictable findings. The results are discussed in terms of the previous literature in the field.     

Assertiveness,self-actualization,and locus of control in women

An intervention program designed to facilitate psychological growth in middle-aged women was implemented and evaluated. Specifically, the study examined the program's effects on the participants in the areas of assertiveness, externality, and self-actualization at the end of the program and five months later. The results showed significant increases in assertiveness and self-actualization in the women at the posttest and five months later. There was no change in locus of control; most of the women were internally oriented at the pretest and remained the same over time.     

Norms on the gender perception of role nouns in Czech,English, French,German, Italian,Norwegian, and Slovak

We collected norms on the gender stereotypicality of an extensive list of role nouns in Czech, English, French, German, Italian, Norwegian, and Slovak, to be used as a basis for the selection of stimulus materials in future studies. We present a Web-based tool (available at https://www.unifr.ch/lcg/) that we developed to collect these norms and that we expect to be useful for other researchers, as well. In essence, we provide (a) gender stereotypicality norms across a number of languages and (b) a tool to facilitate cross-language as well as cross-cultural comparisons when researchers are interested in the investigation of the impact of stereotypicality on the processing of role nouns.