Cross-sectional and longitudinal relationships among age, cognition, and processing speed

Cross-sectional and longitudinal age effects on cognitive function were examined in 302 older adults followed longitudinally. Processing speed was related to cognitive performance at cross-section, and change in speed predicted within-person longitudinal cognitive decline. Statistical control of processing speed greatly reduced cross-sectional age effects but did not attenuate longitudinal aging effects. This difference in processing speed's ability to account for cross-sectional and longitudinal age effects is discussed in the context of theories of cognitive aging and methodological and statistical issues pertaining to the cross-sectional and longitudinal study of cognitive aging.     

Cross-sectional versus longitudinal age gradients of tower of Hanoi performance: the role of practice effects and cohort differences in education

We examined 5-year longitudinal changes in Tower of Hanoi (TOH) performance in a population-based sample of adults (35-85 years initially; n = 1480). An age-matched sample (n = 433) was included to estimate practice effects. The longitudinal age gradients differed substantially from the cross-sectional age gradients. This was the case even when practice effects, that were substantial in magnitude across the young/middle-aged groups, were controlled for. Instead of a continuous age-related deficit in performance from 35 and onwards, longitudinal data showed slowing of performance and increases of illegal moves past age 65. Cohort-related differences in educational attainment did not account for this discrepancy. Further analyses revealed a positive relation between practice-related gains and explicit memory of having performed the task at the first test occasion and a positive association between latent changes in TOH and Block Design, in line with cross-sectional findings. In conclusion, the results demonstrate a pattern of age-related changes indicating a late-onset decline of TOH performance and underscore the need to control for retest effects in longitudinal aging research.     

The fate of cognition in very old age: six-year longitudinal findings in the Berlin Aging Study (BASE)

The authors report full-information longitudinal age gradients in 4 intellectual abilities on the basis of 6-year longitudinal changes in 132 individuals (mean age at T1 = 78.27, age range = 70-100) from the Berlin Aging Study. Relative to the cross-sectional parent sample (N = 516, mean age at T1 = 84.92 years), this sample was positively selected because of differential mortality and experimental attrition. Perceptual speed, memory, and fluency declined with age. In contrast, knowledge remained stable up to age 90, with evidence for decline thereafter. Age gradients were more negative in old old (n = 66, mean age at T1 = 83.04) than in old (n = 66, mean age at T1 = 73.77) participants. Rates of decline did not differ reliably between men and women or between participants with high versus low life-history status. They conclude that intellectual development after age 70 varies by distance to death, age, and intellectual ability domain.     

Performance variability is related to change in cognition: evidence from the Victoria Longitudinal Study

Performance variability across repeated task administrations may be an important indicator of age-related cognitive functioning. In the present investigation, the authors examined whether age differences and change in inconsistency were related to 6-year (3 occasion) cognitive change. Inconsistency scores were computed from 4 reaction time tasks performed by 446 older adults (54-89 years). Replicating previous cross-sectional results, greater inconsistency was observed for older participants even after controlling for differences in response speed. New longitudinal results demonstrated (a) associations between inconsistency at baseline measurement and 6-year change in cognitive performance; (b) longitudinal change in inconsistency; and (c) intraindividual covariation between 6-year change in inconsistency and 6-year change in level of cognitive function. These findings support the view that performance variability serves as a marker of cognitive aging.     

Mortality-Related Differences and Changes in Episodic Memory Among the Oldest Old: Evidence From a Population-Based Sample of Nonagenarians

We examined cross-sectional differences and longitudinal changes in episodic memory performance related to impending death among a group of very old people, aged 90–101 years. Participants were assessed at 3 measurement points across a 6-year interval. Three groups were identified: those who survived the entire follow-up period (n =40), those who died before the first follow-up (n =44), and those who died after the first follow-up (n =14). Participants completed a battery of episodic memory tasks consisting of face recognition, word recognition, word recall, and object recall with selective reminding. Those who survived performed better than those who were going to die in object recall at baseline. A Cox regression analysis, controlling age, revealed that object recall performance was significantly related to subsequent mortality status. Longitudinal analyses demonstrated significant 3-year decline for both face recognition and object recall, but no evidence of differential decline as a function of mortality group. Thus, longitudinal changes in memory preceding death were not as pronounced as the corresponding cross-sectional differences in this very old sample. In general, the results suggest that mortality-related memory deficits are present in extreme old age, although these deficits are relatively small and task-specific.     

Well-being affects changes in perceptual speed in advanced old age: longitudinal evidence for a dynamic link

This study examined competing hypotheses about dynamic cross-domain associations between perceptual speed and well-being in advanced old age. We applied the bivariate dual change score model (J. J. McArdle & F. Hamagami, 2001) to 13-year incomplete longitudinal data from the Berlin Aging Study (P. B. Baltes & K. U. Mayer, 1999; N=516, 70-103 years at T1, M=85 years). Reports of well-being were found to influence subsequent decline in perceptual speed (time lags of 2 years). No evidence was found for a directed effect in the other direction. None of the potential covariates examined (initial health constraints, personality, and social participation) accounted for these differential lead-lag associations. Our results suggest that well-being is not only a consequence of but also a source for successful aging. The discussion focuses on conceptual implications and methodological considerations.     

Longitudinal Changes in Memory Performance and Processing Speed in Old Age abstract Keywords

The speed theory of cognitive aging posits that an age-related slowing of processing speed leads to impairments in higher order cognitive functions, such as memory. However, only few studies have examined the relationship between longitudinal changes in processing speed and longitudinal changes in memory performance. In the present study, data of 474 older adults (T1: 59–65 years) from the Interdisciplinary Longitudinal Study on Adult Development (ILSE) were used to investigate whether changes in speed and in memory were associated over a 4-year period. Performance changes in both constructs were analyzed using latent change factor models. Results show that latent changes in processing speed and latent changes in memory performance correlated with 0.61. This association is considerably lower than what would have been expected from cross-sectional data. Our longitudinal results suggest that although speed changes explain a substantial proportion of variance in memory changes, additional explanatory factors must be taken into consideration.     

Evaluating the interdependence of aging-related changes in visual and auditory acuity,balance, and cognitive functioning

High proportions of shared age-related variance are found among measures of perceptual acuity, balance, muscle strength, and cognitive capabilities in age-heterogeneous, cross-sectional studies. Reliance on cross-sectional studies is problematic, however, because associations may arise from age-related mean trends. Narrow age-cohort samples provide an alternative basis for testing hypotheses regarding associations among rates of change. Cross-domain associations were evaluated in combined 75-year-old cohort samples from Denmark, Finland, and Sweden. In general, no consistent associations were found across sensory, balance, strength, and cognitive domains. These findings indicate that the effects of aging on sensory acuity, balance, and cognitive functioning are likely to be largely independent, multidimensional, and complex at the level of the individual.     

Social participation attenuates decline in perceptual speed in old and very old age

Does an engaged and active lifestyle in old age alleviate cognitive decline, does high cognitive functioning in old age increase the possibility of maintaining an engaged and active lifestyle, or both? The authors approach this conundrum by applying a structural equation model for testing dynamic hypotheses, the dual change score model (J. J. McArdle & F. Hamagami, 2001), to 3-occasion longitudinal data from the Berlin Aging Study (Time 1: n=516, age range=70-103 years). Results reveal that within a bivariate system of perceptual speed and social participation, with age and sociobiographical status as covariates, prior scores of social participation influence subsequent changes in perceptual speed, while the opposite does not hold. Results support the hypothesis that an engaged and active lifestyle in old and very old age may alleviate decline in perceptual speed.     

Episodic memory change in late adulthood: Generalizability across samples and performance indices

Younger adults recall more information from episodic memory tasks than do older adults. Because longitudinal studies are rare and often incompatible, the extent of actual late-life memory change is not well established. We assemble two different longitudinal samples of normal older adults, each of which is tested twice at a 3-year interval, using a large battery of episodic memory indicators. Together, two-wave data from both the Victoria Longitudinal Study in Canada (n = 400) and the Kungsholmen Project in Sweden (n = 168) cover a 40-year span of adulthood, ranging from 54 to 94 years of age. Principal memory tasks include categorizable word lists, story recall, and random word lists, as well as indicators of cognitive support. Overall, an examination of performance on sets of common and complementary episodic tasks reveals that, for both samples, actual 3-year changes are modest and that, when decline occurs, it is gradual. The exception-greater decline for more supported tasks-suggests that these may be especially sensitive to late-life changes.     

Sustained attention in adulthood: a unique, large-sample, longitudinal and multicohort analysis using the Mackworth Clock-Test

A cross-sectional sample of men (n = 177) tested in 1962-1964, and men (n = 188) and women (n = 113) tested in 1980-1984, and a longitudinal sample (n = 53) of men tested in 1962-1964 and 1980-1984, were used to investigate age differences and 18-year age changes on a 62-min sensory vigilance task that made virtually no demand on memory, the Mackworth Clock-Test. Age differences and changes in the vigilance decrement were also examined. No age differences or changes were obtained for detection accuracy. Target response time showed significant age-related 18-year longitudinal changes and one significant cross-sectional age difference; the overall age effect was of a U-shaped function with a minimum at middle age. Age differences and changes were obtained in a measure of arousal: skin potential response latency; the overall age effect was also consistent with a U-shaped function. There was little consistent evidence of a differential effect of age on the vigilance decrement. Outcomes contradictory to Surwillo and Quilter (1964) and Quilter, Giambra, and Benson (1983) are reconciled through additional statistical analyses.     

A longitudinal study of the performance of hypertensive and normotensive subjects on the Wechsler Adult Intelligence Scale

Performance on the Wechsler Adult Intelligence Scale was followed over two 5- to 6-year intervals for essential hypertensive Ss (EH; n = 22) free from medical complications and for normotensive Ss (N; n = 20). EH were treated with adrenergic beta-blocking drugs, diuretics, or both. Mean age was 46 years (SD = 12.6 years), initially (Time 1). Results were unaltered by adjustment for initial age. N improved modestly on the Verbal scale, from Time 1 to Time 2 only. EH neither improved nor declined on the Verbal scale. Scores remained unchanged for both EH and N Ss for the Performance scale. Overall, and at Times 2 and 3, Verbal scores were lower for the EH group. It was concluded that neither decline nor improvement in cognitive function over time are necessary outcomes of modest, carefully treated, uncomplicated hypertension in the middle years.     

Lead us not into temptation: Differential associations of religious identification with self-regulatory traits and abilities

While there has been considerable research on the link between religiosity and self-regulation, the directionality of both constructs remains equivocal. Moreover, little is known regarding the association between religiosity and performance-based measures of self-regulatory abilities, given that past studies have predominantly examined self-regulatory traits via self-reports. Drawing from a 9-year longitudinal dataset (Time 1: n = 4836; Time 2: n = 3467), cross-sectional findings indicated that religious identification was positively and negatively correlated with self-regulatory traits and abilities, respectively. Longitudinal findings revealed that self-regulatory abilities predicted negative changes in religious identification, and this effect strengthened from middle to late adulthood. No longitudinal relations between religious identification and self-regulatory traits were found. Our findings highlight the differential associations of religious identification with self-regulatory traits and abilities, and how these associations are modulated by advancing adulthood.     

Proactive interference in working memory is related to adult age and cognitive factors: cross-sectional and longitudinal evidence from the Betula study

ABSTRACT

In working memory (WM), successful maintenance of information is affected by interference. Older adults may be especially susceptible to the effects of interference, which may cause age-related cognitive impairments. A relative score of IC was derived from cross-sectional (n = 869) and longitudinal (n = 443) data to investigate (1) if IC is reduced in normal aging, (2) if individual differences in IC related to individual performance in other cognitive domains, and (3) if 5-year change in IC is related to change in general cognition. Older age was associated with reduced IC, but no decline in IC occurred over 5 years. Also, the ability to control interference in WM was related to performance in episodic memory, verbal fluency, and block design. We also found that IC mediates the relationship between age and cognition, suggesting that age-related cognitive decline is linked to IC. Finally, we demonstrate that change in IC was related to decline in episodic memory.     

ANTECEDENTS AND CONSEQUENCES OF PSYCHOLOGICAL WORKPLACE STRAIN DURING EXPATRIATION: A CROSS-SECTIONAL AND LONGITUDINAL INVESTIGATION

In this study, we examined nonlinear/interaction effects associated with the antecedents and consequences of psychological workplace strain, using cross-sectional ( N = 165) and longitudinal ( N = 133) data collected from Western expatriates in China. The results of this study indicate that family characteristics interact to affect the level of psychological workplace strain experienced by expatriates. In addition, we find an inverse u-curve relationship between psychological workplace strain and supervisory rated job performance for both cross-sectional and longitudinal analyses. Finally, the empirical results lend support to the hypothesized positive relationship between work adjustment measured at Time 1 and job performance measured at Time 2. Implications for expatriate adjustment research and practice are discussed.     

Is age-related stability of subjective well-being a paradox? Cross-sectional and longitudinal evidence from the Berlin Aging Study

Subjective well-being is thought to remain relatively stable into old age despite health-related losses. Age and functional health constraints were examined as predictors of individual differences and intraindividual change in subjective well-being, as indicated by positive and negative affect, using cross-sectional (N = 516) and longitudinal (N = 203) samples from the Berlin Aging Study (age range 70-103 years). In cross-sectional and longitudinal analyses, age and functional health constraints were negatively related to positive affect but unrelated to negative affect. Cross-sectionally, controlling for functional health constraints reversed the direction of the relationship between age and positive affect and produced a negative association between age and negative affect. Findings suggest two qualifications to the average stability of overall subjective well-being: Only some dimensions of subjective well-being remain stable, while others decline; age per se is not a cause of decline in subjective well-being but health constraints are.     

The factor structure and factorial invariance of the 12-item General Health Questionnaire (GHQ-12) across time: evidence from two community-based samples

This study provides new knowledge about the factor structure of the 12-item General Health Questionnaire (GHQ-12; D. Goldberg, 1972) through the application of confirmatory factor analysis to longitudinal data, thereby enabling investigation of the factor structure, its invariance across time, and the rank-order stability of the factors. Two community-based longitudinal adult samples with 1-year (n = 640) and 6-year (n = 330) follow-up times were studied. As a result, the correlated 3-factor model (i.e., Anxiety/Depression, Social Dysfunction, and Loss of Confidence) showed a better fit with both samples than the alternative models. The correlated 3-factor structure was also relatively invariant across time in both samples, indicating that the scale has good construct validity. The rank-order stabilities of the factors were low across time, which suggests that the GHQ-12 measures temporal mental state.     

Is Obstructive Sleep Apnoea Related to Neuropsychological Function in Healthy Older Adults? A Systematic Review and Meta-Analysis

Previous systematic reviews and meta-analyses have identified cognitive deficits in adults with obstructive sleep apnoea (OSA). However, quantitative analysis of the association between OSA and neuropsychological performance has not been conducted specifically in older adults, for whom there is a greater risk of cognitive decline. We searched Medline, Embase and PsycINFO through August 2016 for studies describing associations between OSA and neuropsychological outcomes in people aged>50 years. Meta-analyses were performed on these studies for overall cognition and within cognitive domains. Subgroup analyses were performed taking into account risk of bias and moderating differences in study design. 13 studies met eligibility criteria for analysis. A small negative association was found between OSA and all neuropsychological outcomes combined, g=0.18(95% CI 0.04–0.32), and in memory and processing speed domains. Small case-control studies from sleep clinic populations observed the greatest associations, while larger cohort studies from community samples illustrated no association. Analysis accounting for publication bias resulted in a null overall association, g=0.02 (95%CI -0.12 to 0.16). Associations between OSA and cognition in later life are highly variable and the findings differ based on the type and setting of study. It appears some older adults may be at risk of cognitive impairments attributable to OSA; however, the risk of bias renders the evidence inconclusive. High quality research is warranted in clinically diagnosed OSA patients as well as those already experiencing neuropsychological impairment and who may be regarded at higher risk of further cognitive decline.     

The relations between phonological processing abilities and emerging individual differences in mathematical computation skills: a longitudinal study from second to fifth grades

The primary purpose of this longitudinal correlational study was to examine relations between phonological processing abilities and emerging individual differences in math computation skills and also to investigate the source of covariation between reading and math computation skills in a random sample (n = 201). Phonological memory, rate of access to phonological codes in long-term memory, and phonological awareness were uniquely associated with growth in estimated total number of computation procedures mastered (general computation skills) from 92.5 to 134.8 months in age, although the contributions of the first two abilities were developmentally limited. Phonological processing almost completely accounted for the associations between reading and general computation skills. Evidence of bidirectional relations between general computation skills and simple arithmetic problem solving speed was found.     

A Two-Year Longitudinal Study of Neuropsychological and Cognitive Performance in Relation to Behavioral Problems and Competencies in Elementary School Children

Despite interest in early neuropsychological status as a possible contributor to children's behavioral development, prospective longitudinal investigations of neuropsychological measures in relation to later behavioral outcomes in childhood are few. A 2-year longitudinal study in a nonselected childhood sample is reported. The study tested the influence of early neuropsychological performance (verbal fluency, mental inhibitory control, and visual spatial ability) on later childhood behavioral problems and social competency. Regular education children (n = 235) were assessed at three time points 1 year apart. To control for autocorrelation of outcome measures, Time 1 behavior was partialed while testing the effects of Time 1 neuropsychological scores on Time 3 outcome. To control for autocorrelation of neuropsychological scores, Time 2 scores were partialed while testing the predictive effect of Time 1 scores on Time 3 outcome. Both sets of regression models suggested modest but statistically significant effects for inhibitory control and verbal fluency, but not IQ, reading, or visual spatial ability, on behavioral outcome. Study results are consistent with a modest causal effect of selected neuropsychological skills on later behavioral adjustment. The findings support theories that implicate subtle neuropsychological dysfunction in the development of behavioral problems in childhood.