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Interhemispheric transfer of lever pressing as stimulus generalization of the effects of spreading depression
Authors:Allen M. Schneider and Ebbe Ebbesen
Abstract:Rats trained to lever-press with spreading depression in one cerebral hemisphere showed weak responding when tested with depression shifted to the trained hemisphere. The rats were then divided into two groups: one group (normal) was permitted a single reinforced response with neither hemisphere depressed, the other group (depressed) was permitted a single reinforced response with the trained hemisphere depressed; both groups were then tested with the trained hemisphere depressed. Responding during this second test increased for both groups, but the magnitude of the increase tended to be greater for the depressed than for the normal group. Since memory transfer could not have occurred with the trained hemisphere depressed, the results were taken to indicate that the single reinforced response strengthened stimulus generalization between train-test conditions.
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