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咪达唑仑—舒芬太尼靶控输注辅助神经阻滞用于颈部手术临床观察
引用本文:孙振涛,韩雪萍,徐广,王勇,田丹丹.咪达唑仑—舒芬太尼靶控输注辅助神经阻滞用于颈部手术临床观察[J].医学与哲学,2009(9):32-33,39.
作者姓名:孙振涛  韩雪萍  徐广  王勇  田丹丹
作者单位:郑州大学第一附属医院麻醉科,河南省高等学校临床医学重点学科开放实验室,河南郑州450052
基金项目:河南省医学科技攻关项目,项目编号:200703020
摘    要:观察咪达唑仑复合舒芬太尼TCI及恒速输注辅助颈丛阻滞颈部手术的镇痛镇静效果及对术中知晓、血液动力学和呼吸的影响,将80例择期颈部手术患者,随机分为2组各40例:咪达唑仑复合舒芬太尼TCI组(A组);咪达唑仑复合舒芬太尼恒速输注组(B组)。比较二组MAP,HR,RR,SpO2等及术中镇痛、镇静、术中知晓和各种不良反应发生情况。发现A组血液动力学较B组更加稳定。提示TCI辅助颈丛阻滞麻醉安全有效,镇痛良好,无术中知晓,较恒速输注血液动力学更稳定,呼吸抑制少。

关 键 词:咪达唑仑  舒芬太尼  靶控输注  神经阻滞  镇痛

Midazolam and Sufentanil Combined with Target--controlled Infusion Assist Cervical Plexus Block on Cervical Surgery
Institution:SUN Zhen-tao, HAN Xue ping, XU Guang ,et al. (Department of Anesthesiology, the First Affiliated Hospital of ZhengZhou University, ZhengZhou 450052, China)
Abstract:The purpose of this study is to evaluate the effects on sedation, hemodynamic and respiratory of Midazolam and Sufentanil combined with target--controlled infusion (TCI) and constant infusion assist cervical plexus block on cervical surgery. 80 elective cervical surgery patients were randomly divided into two groups:Midazolam and Sufentanil TCI group (group A); midazolam and sufentanil constant infusion group (group B) 40 cases each. MAP, HR, RR, SpO2 changes were recorded. Sedation, respiratory depression, muscle stiffness, nausea and vomiting, pruritus, and other adverse reactions were recorded,too. A group hemodynamics were more stable than group B. Therefore, Midazolam and Sufentanil combined with TCI assist cervical plexus block for cervical surgery is safe and effective.
Keywords:Midazolam  Sufentanil  target-- controlled infusion  cervical plexus block  sedation
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