Quantification of brain lesions using interactive automated software |
| |
| Authors: | Milan?Makale,Jeffrey?Solomon,Nicholas?J.?Patronas,Adrian?Danek,John?A.?Butman,Jordan?Grafman author-information" > author-information__contact u-icon-before" > mailto:grafmanj@ninds.nih.gov" title=" grafmanj@ninds.nih.gov" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author |
| |
| Affiliation: | 1.H. M. Jackson Foundation,Bethesda;2.Sensor Systems Incorporated,Sterling;3.Cognitive Neuroscience Section, National Institute for Neurological Disorders and Stroke,National Institutes of Health,Bethesda |
| |
| Abstract: | We developed an interactive program, Analysis of Brain Lesions (ABLe) so that researchers studying the effects of brain lesions on cognition could have a user-friendly tool that could quantitatively characterize such lesions. The program was prepared in Tcl/Tk and will run on any UNIX or PC LINUX platform with the MEDx medical imaging software package. The ABLe is almost completely automated and determines the brain lesion size as well as which cytoarchitectonic brain regions (Brodmann areas) are contained within the boundaries of the lesion. Lesion data from multiple subjects can be grouped together and the degree of lesion overlap displayed. All images are analyzed and displayed within standard Talairach coordinate space, and the precision of the match between the ABLe Brodmann area graphics and the subject/patient brain is easily confirmed. The program is the first easy-to-use software that contains these specific features and is available for interested researchers with a background in lesion analysis. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
