Apple II/FIRST system control of electrical brain stimulation in the rabbit

An Apple II/FIRST system has been developed to control classical conditioning experiments, collect analog data, and extract dependent variable measures of conditioning from uniphasic (Scandrett & Gormezano, 1980) and multiphasic (Johnson, 1981) response signals. The present paper details the development of an electrical brain stimulation system as a peripheral device to the Apple II/FIRST system. In addition, data are presented that document the capabilities of the EBS system to concurrently stimulate up to eight animals while values along the dimension of each of four stimulation parameters are manipulated by a program written in FIRST. In our judgment, the EBS system has a number of advantages over currently available commercial stimulators, including cost, number of sites that can be independently stimulated, and availability of complete software control.