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An estimating equations approach for the LISCOMP model
Authors:Beth A. Reboussin  Kung-Yee Liang
Affiliation:(1) Department of Public Health Sciences, Medical Center Boulevard, Wake Forest University School of Medicine, 27157 Winston-Salem, NC;(2) School of Hygiene and Public Health, Johns Hopkins University, USA
Abstract:Maximum likelihood estimation is computationally infeasible for latent variable models involving multivariate categorical responses, in particular for the LISCOMP model. A three-stage generalized least squares approach introduced by Muthén (1983, 1984) can experience problems of instability, bias, non-convergence, and non-positive definiteness of weight matrices in situations of low prevalence, small sample size and large numbers of observed indicator variables. We propose a quadratic estimating equations approach that only requires specification of the first two moments. By performing simultaneous estimation of parameters, this method does not encounter the problems mentioned above and experiences gains in efficiency. Methods are compared through a numerical study and an application to a study of life-events and neurotic illness.The authors would like to thank Bengt Muthén for many helpful discussions and Scott Henderson for generously providing the Canberra data set. This work was supported in part by grant number GM49909 of the National Institutes of Health.
Keywords:estimating equations  latent variable  LISCOMP model  multivariate binary data
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