Deficits in set-shifting ability in nonclinical compulsive checkers

Recent studies suggest deficits in set-shifting ability in patients with obsessive-compulsive disorder (OCD) as measured by tasks such as the Wisconsin Card Sorting Test (WCST; Berg, 1948). The present study examined the extent to which these deficits were demonstrated by nonclinical subjects selected on the basis of their checking scores on the Maudsley Obsessional-Compulsive Inventory. A multivariate analysis revealed that frequent checkers performed significantly worse on the WCST than noncheckers, making more total errors and more perseverative errors and requiring more time to complete the test. A follow-up analysis on a subset of the original sample found similar performance deficits in checkers. While the poorer performance of checkers could be statistically accounted for by anxiety during the first administration of the WCST, anxiety could not explain the relationship between checking status and WCST performance at follow-up. Therefore, there does appear to be some relationship between checking status and WCST performance beyond what can be explained by affective variables.