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Regional cerebral blood flow response in a patient with remitted global amnesia
Authors:Frank Wood  Lawrence McHenry  Gustavo Román-Campos  Charles M. Poser
Affiliation:Bowman Gray School of Medicine of Wake Forest University USA;University of Vermont, College of Medicine USA
Abstract:A case of remitted global amnesia, believed to have residual left medial temporal lobe damage, is tested by the same recognition memory paradigm used by Wood, Taylor, et al. in the previous paper. On two different testing occasions, once using an intentional and once an incidental memory procedure, the patient's right occipital flows were inversely correlated with memory accuracy and the values were very close to the regression line for 10 normals relating occipital flow to memory accuracy. The left occipital flows did not fit the regression line, however. The results were interpreted as consistent with the notion that occipital flow is inversely related to medial temporal lobe activation. Another surprising feature of this case is the unexpected persistence of amnesia for a period from about 5 to 10 years before her episode to about 2 weeks after the episode, with recovery of memory functioning for the period since that time.
Keywords:Address reprint requests to Dr. Frank Wood   Section of Neuropsychology   Department of Neurology   Bowman Gray School of Medicine of Wake Forest University   Winston-Salem   North Carolina   27103.
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