Schizophrenic tendencies and memory deficits in normals

The report tests the hypothesis that normals who exhibit schizophrenic tendencies are likely to show verbal-memory deficits of the types observed in schizophrenics. Thirty-four middle-aged men were tested using the MMPI 2–7–8 schizophrenic-tendency scales, the Sorting Consistency Task and the Physical Anhedonia Scale. The dependent variables were four memory tests selected on the basis of their known discriminating power and their relevance. The results showed the Schizophrenia (8) and Psychasthenia (7) scales of MMPI, and the Sorting Consistency Task effectively detected memory deficits in normals. When partialling out intelligence, as a measure of general current cognitive functioning, it appeared that one of the deficits reflecting encoding difficulty disappeared. This suggests that normal ‘high-risk’ subjects for schizophrenia show a ‘generalized deficit’, which affects memory in addition to a ‘differential deficit’ in retention. Though tentative, the results can be taken as an indication that ‘high-risk’ subjects indeed show memory deficits and that detecting these deficits requires relatively sensitive tools.