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Factors Associated with Functional Dependence in Alzheimer's Disease
Authors:Chooyon Cho  Hangsuk Cho  Kyunghee Cho  Kyounggyu Choi  Heejong Oh  Chulyoung Bae
Affiliation:(1) Department of Family Medicine, Soonchunhyang University School of Medicine, 657-58, Hannam-Dong, Yongsan-Ku, Seoul, 140-743, South Korea;(2) Department of Family Medicine, Kwandong University School of Medicine, Myungji Hospital, Hwajeong-Dong, Koyang, Kyunggi-Do, 412-270, South Korea;(3) Department of Geriatric Medicine, Sungnam Hospital, 5113-1, Sungnam, Kyunggi-Do, 461-191, South Korea;(4) Department of Neurology, Ewha University School of Medicine, 911-1, Mok-Dong, Yangchon-Ku, Seoul, 158-710, South Korea;(5) Department of Neurology, Catholic University of Taegu-Hyosung, School of Medicine, 3056-6, Daemyung-4 Dong, Nam-Ku, Taegu, 705-034, South Korea;(6) Department of Family Medicine, Pochon-CHA University School of Medicine, 351, Yatap-Dong, Sungnam, Kyunggi-Do, 463-070, South Korea
Abstract:The purpose of this study was to determine whether common geriatric conditions, family function, and nutritional problems have independent associations with functional dependence beyond the effect of cognitive impairment in patients with Alzheimer's disease. It was found that some common geriatric conditions affecting patients with Alzheimer's disease appear to have multiple and differential relationships with specific instrumental activities of daily living (IADLs) dependency. These results have implications for medical care. Preventing one condition may not be sufficient to prevent further IADL dependences because the conditions are independently related to individual outcome variables. Thus, multiple conditions may need to be managed concurrently if further functional dependence is to be expected.
Keywords:Alzheimer's disease  functional dependence  IADLs
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