Male and female psychoneuroendocrine response to examination stress: A case report

Urinary catecholamine levels were investigated in one female and one male Ph.D. candidate during public defense of their Ph.D. theses as well as during 2 weeks preceding and 1 week following these examinations. Although females, in comparison to males, usually tend to show a weak adrenaline response to mental stress, a threefold increase was observed in both subjects. The results support the assumption that sex differences in adrenal-medullary responsiveness to stress is not determined by sex-specific biological factors alone and that a “male” responsiveness may be observed in achievement-oriented females exposed to a challenging real-life situation. Effects on urinary measures of cortisol obtained from the male subject resembled effects on adrenaline, showing that this kind of real-life stressor affects the sympathetic-adrenal medullary and the pituitary-adrenocortical systems similarly.