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Family and psychosocial predictors of obsessive compulsive disorder in a community sample of young adolescents
Authors:Laura A. Valleni-Basile M.S.P.H.  Carol Z. Garrison Ph.D.  Kirby L. Jackson A.B.  Jennifer L. Waller Ph.D.  Robert E. McKeown Ph.D.  Cheryl L. Addy Ph.D.  Steven P. Cuffe M.D.
Affiliation:(1) Department of Epidemiology and Biostatistics, School of Public Health, University of South Carolina, 29208 Columbia, SC;(2) Department of Epidemiology and Biostatistics, Associate Provost and Dean of the Graduate School, University of South Carolina, Columbia, South Carolina
Abstract:A two-stage epidemiologic study conducted between 1986 and 1988 in the southeastern United States investigated family and psychosocial predictors of obsessive compulsive disorder (OCD) and subclinical OCD in young adolescents. In the first stage, a life-event schedule and a family adaptability and cohesion scale were administered to a community sample of 3,283 adolescents. In stage two, the Schedule for Affective Disorders and Schizophrenia in School Age Children and the Children's Global Assessment Scale were administered to 488 mother-child pairs. In multivariable models family cohesion was the only significant correlate of OCD (odds ratio=0.95, 95% confidence interval 0.91–0.98). Gender, race, age, socioeconomic status, guardian status, adaptability, undesirable life events and desirable life events were not found to be significant predictors of OCD in models adjusting for cohesion. Note of the above variables were significantly associated with subclinical OCD. However, separate analyses of the 41 individual life events indicated seven specific events were significantly associated with OCD or subclinical OCD. These findings are at odds with the theory that overinvolvement of family members is a risk factor for OCD, though an association with overly rigid family structure cannot be eliminated based on these data. Further exploration of family characteristics is warranted.
Keywords:obsessive compulsive disorder  community sample  adolescent  cohesion  adaptability  life events
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