| 从系统论分析慢性炎症向肿瘤的恶性转化 |
| |
| 引用本文： | 应力,程现昆,夏星海,周密. 从系统论分析慢性炎症向肿瘤的恶性转化[J]. 医学与哲学(人文社会医学版), 2011, 0(1): 55-56 |
| |
| 作者姓名： | 应力 程现昆 夏星海 周密 |
| |
| 作者单位： | [1]大连医科大学附属第二医院,辽宁大连116027 [2]大连医科大学社会科学与管理科学学院,辽宁大连116044 [3]中国医科大学,辽宁沈阳110001 |
| |
| 摘 要： | 慢性炎症相关肿瘤疾病，其机制涉及到的不再是个别的基因产物或蛋白分子，也不再是单一的信号通路或代谢途径，而是众多的基因、蛋白质和代谢小分子等各种生物分子构成的复杂的调控网络。这一网络中的相互联系、动态以及突变特性，要求运用系统论的方法来分析。这种分析将拓展临床医生的研究思路，推动对炎症向肿瘤转化本质的认识。
|
| 关 键 词： | 炎症 肿瘤 系统论 方法论 |
Analysis of Malignant Transformation of Chronic Inflammation Using System Theory |
| |
| Affiliation: | YING Li, CHENG Xian-kun, XIA Xing-hai ,et al. (The Second Hospital of Dalian Medical University, Dalian 116027, China ) |
| |
| Abstract: | The pathogenesis of inflammation--associated tumor involves in a complicated network regulated by multiplex rather than individual genes, proteins and metabolic molecules. Based on the principles of integrity, dynamic quality and universal connection and catastrophe model in system theory, the clinicians are capable of investigating the mechanism of malignant tumor with philosophy methodology which may subsequently broaden their sights in research studies. |
| |
| Keywords: | inflammation tumor system theory methodology |
| 本文献已被 维普 等数据库收录！ |
|
