Natural ways are better: Adolescents and the ‘anti-obesity’ gene

Empirical research with young people in Finland, Germany, Spain and Britain was carried out as part of the BIOCULT project funded by the European Union. The project focused on their attitudes to biotechnology and, in particular, the formation of arguments about risk and safety. This paper looks at the responses of 14–18 year olds to a story about the so called anti-obesity gene, in the form of advice to a friend who is taking it. The majority advised against taking it with some differences by gender and country. Most reservations were on grounds of safety and the feeling that ‘natural’ ways to lose weight are better: A minority questioned the idea of striving for a ‘perfect’ body. The types of arguments used by the young people reveal underlying perspectives on the place of human beings in the world and whether they have a right to manipulate nature and their own bodies. Marie Levitt is a sociologist with research interests in attitudes and values in relation to biotechnology, health and religion.     

Keeping Up with the Cloneses -- Issues in Human Cloning

The advent of cloning animals has created a maelstrom of social concern about the ethical issues associated with the possibility of cloning humans. When the ethical concerns are clearly examined, however, many of them turn out to be less matters of rational ethics than knee-jerk emotion, religious bias, or fear of that which is not understood. Three categories of real and spurious ethical concerns are presented and discussed: 1) that cloning is intrinsically wrong, 2) that cloning must lead to bad consequences, and 3) that cloning harms the organism generated. The need for a rational ethical framework for discussing biotechnological advances is presented and defended.     

Social and ethical dimensions of nanoscale science and engineering research

Continuing advances in human ability to manipulate matter at the atomic and molecular levels (i.e. nanoscale science and engineering) offer many previously unimagined possibilities for scientific discovery and technological development. Paralleling these advances in the various science and engineering subdisciplines is the increasing realization that a number of associated social, ethical, environmental, economic and legal dimensions also need to be explored. An important component of such exploration entails the identification and analysis of the ways in which current and prospective researchers in these fields conceptualize these dimensions of their work. Within the context of a National Science Foundation funded Research Experiences for Undergraduates (REU) program in nanomaterials processing and characterization at the University of Central Florida (2002–2004), here I present for discussion (i) details of a “nanotechnology ethics” seminar series developed specifically for students participating in the program, and (ii) an analysis of students’ and participating research faculty’s perspectives concerning social and ethical issues associated with nanotechnology research. I conclude with a brief discussion of implications presented by these issues for general scientific literacy and public science education policy.     

Shooting Genes,Distributing Credit: Narrating the Development of the Biolistic Gene Gun

Using oral histories with scientists, technology transfer managers and other collaborators who were involved with the development of the biolistic gene gun, I investigate how actors narrate their experiences of technology transfer. The individuals who worked on the gene gun draw on two different interpretive repertoires for describing the innovation process: a ‘localized’ repertoire that highlights defined moments and the conceptual contributions of a few individuals; and a ‘distributed’ repertoire that emphasizes longer time frames, the process of technical implementation and the importance of a network of collaborators. Each of these repertoires identifies a different assemblage of actors as deserving of credit and reward for the development of the gene gun. Examining how scientists employ these modes of describing the innovation process offers a way of thinking about how university inventors negotiate tensions around novel features of academic capitalism, such as personal profit arising from the commercialization of university technologies.     

The structure of “communities” and communications in the new millennium

The three lineages of information,—the genetic, the cultural and artifactual—will increasingly merge their constituent information contents through advances in biotechnology and information technology. This will redefine what constitutes “social” and what constitutes “community.” A community's members communicate with their “significant others” and change their internal information states (and their internal and external behaviors). Under conditions of merging, information exchanges occur across all the three lineages. In this sense, the concept of significant other,—that is, a communicating entity—, is now spread from human communities to encompass also the biological and the artifactual. A seamless merging between the three realms now occurs affecting their respective internal information stores. The resulting image of interactions that now arises is of multiple oceans of communities, operating at different levels, the genetic, the cultural and the artifactual. There are exchanges across the different levels, up and down and sideways, as information is translated from one realm to the other. These dynamics result in changes in the evolutionary characteristics of each lineage and sub‐lineage, including the internal perceptions from within a lineage, namely in the language of evolutionary epistemology, its “meanings” and “hypotheses” on the world. A future sociology must necessarily take into account these factors and incorporate the dynamics of all three realms.     

Protecting God from Science and Technology: How Religious Criticisms of Biotechnologies Backfire

Many religious critics argue that biotechnology (such as cloning and genetic engineering) intrudes on God's domain, or plays God, or revolts against God. While some of these criticisms are standard complaints about human hubris, I argue that some of the recent criticism represents a "Promethean" concern, in which believers unreflectively seem to fear that science and technology are actually replicating or stealing God's special deity–defining powers. These criticisms backfire theologically, because they diminish God, portraying God as an anthropomorphic superbeing whose relevance and special nature are increasingly rivaled by human power.     

现代生物技术前沿与创新药物研究的思考

生物技术是当今世界发展最快,潜力最大和影响最深远的高新技术之一。极大地推动着创新药物研究的发展,在基因组学,蛋白质组学,生物信息学和生物芯片等几个生物技术前沿大大拓展了创新药物研究的方法和理论,使创新药物研究具有前所未有的广阔的用武之地。     

Biotechnology in the Japanese media: Comparative analysis of newspaper articles on genetic engineering in Japan and Europe

The present study examined how the representations of biotechnology using genetic engineering have been developed in Japan relying on media analysis. Specifically, using the online database of the Asahi Shimbun , one of the major opinion-forming newspapers in Japan, the annual numbers of articles concerning biotechnology were tallied from 1985 to 2000, and an analysis was conducted of the content of 850 articles from 10 particular years. Specifically, a framework in which a biotechnological issue was presented was focused on; the changes of dominant frames and the relationships between frames and specific biotechnological applications (e.g. medicine, agrifood and cloning) were investigated. The results showed that: (i) the number of articles increased sharply in particular since 1996–1997; (ii) although general attitudes toward biotechnology were persistently positive, a frame of biotechnological article became more diverse (i.e. the prospect frames were considerably dominant in the earlier phases, but the concern frames also became prominent in the later phases); and (iii) several articles were found which reported cloned animals in a frame of emotional attachment, a frame unique to Japan. These results were compared with those of European countries and discussed from a perspective of the theory of collective symbolic coping.     

Conflict of interest from a Romanian geneticist’s perspective

This paper examines Romanian bioethics regulations for biomedical sciences, looking in particular at the genetics area as a source for conflict of interest. The analysis is focused on the organizational level, national regulations, the sources for generating conflicts of interest, and management of conflicts. Modern biotechnology and gene technology are among the key technologies of the twenty-first century. The application of gene technology for medical and pharmaceutical purposes is widely accepted by society, but the same cannot be said of the development and application of gene technology in agriculture and food processing. Because the use of a technology in the production and processing of food is regarded more sceptically than in the production of biomedical products, there can be areas of conflict in many cases when communication is undertaken about gene technology in the agro-food sector. Ethical concerns play an important factor in this, but a society’s attitude to a developing technology is an amalgam of many effects which are beyond ethics as such. This paper contains a study carried out by the author for the Romanian Association for Consumer Protection about the attitudes of consumers towards genetically modified (GM) foods. This study revealed that in Romania more than 98% of consumers did not know anything about GM foods and frequently were confused about the definitions of these terms. In conclusion, it is necessary to say that there is a low level of knowledge regarding biotechnology in Romania and this is an important reason why there is neither public acceptance of gene technology products nor is there a rejection. An earlier version of this paper was presented at an International Conference on “Conflict of Interest and its Significance in Science and Medicine” held in Warsaw, Poland on 5–6 April, 2002. Ioana Ispas, MD in Molecular Biology, is a scientific researcher and Member of the Romanian Association for Consumer Protection, NCP for FP5-Quality of life and management of living resources.     

Property rights and genetic engineering: Developing nations at risk

Eighty percent of (commercial) genetically engineered seeds (GES) are designed only to resist herbicides. Letting farmers use more chemicals, they cut labor costs. But developing nations say GES cause food shortages, unemployment, resistant weeds, and extinction of native cultivars when “volunteers” drift nearby. While GES patents are reasonable, this paper argues many patent policies are not. The paper surveys GE technology, outlines John Locke’s classic account of property rights, and argues that current patent policies must be revised to take account of Lockean ethical constraints. After answering a key objection, it provides concrete suggestions for implementing its ethical conclusions.