Comprehension and expression of affect in language-impaired children

Eight children with developmental language impairment (LI) and eight age-, sex-, socioeconomic-status-, and I.Q.-matched controls were given tests of comprehension and expression of affective intent in spoken language and through facial expression. The LI children performed significantly more poorly than did controls in both comprehension and spontaneous expression of vocal affect. On tasks involving emotional facial expression, the opposite results were observed: The LI children were more dramatic in their expression of facial affect than were the controls. Children with language impairment appear to have a deficit in affective comprehension and expression that is modality-specific, i.e., limited to vocal affect. The heightened range of affective facial expression that they demonstrate may be a compensatory mechanism to offset their difficulties with vocal affect.This work was supported by grant 12-203 from the March of Dimes Birth Defects Foundation, and by NINDS grant NS22343 for the Center for the Study of the Neurological Basis of Language.     

Early lexical development in children with focal brain injury

Early lexical development in 27 children with focal brain injury was studied cross-sectionally and longitudinally. Data were obtained from children between 12 and 35 months of age who acquired their lesion prenatally or within the first 6 months of life. Results for the group as a whole provide clear evidence for delays in lexical comprehension and production, and for a larger number of comprehension/production dissociations than would be expected by chance. In addition, a significant number of children were observed having unusual difficulty mastering predication and/or using an atypically high proportion of closed class words (suggesting reliance on holistic/formulaic speech). Analyses by lesion type revealed no effect of lesion size. Analyses according to side of lesion revealed that children with right-hemisphere damage produced a higher proportion of closed class words, suggesting heavy reliance on well-practiced but under-analyzed speech formulae. Children with left-hemisphere damage were slightly better in comprehension than children with right-hemisphere damage. In addition, left posterior lesions were associated with greater delays in expressive language, and delays were more protracted in children with left posterior damage. No differential effects of left posterior damage were found for lexical comprehension.     

异体造血干细胞移植问题、发展与思考

异体造血干细胞移植(Allo-HSCT)已成为治疗恶性血液病及其他各种疾病的有效方法之一。在Allo-HSCT中由于供体和受体免疫屏障的存在。从而一开始就是一个供受体矛盾的对立统一的过程。对其中矛盾的研究和解决充满了辩证唯物的哲学思想。也促使Allo-HSCT技术不断发展。新的方法和理念不断出现。使Allo-HSCT治疗白血病的疗效不断提高。     

Visual attention in infants with perinatal brain damage: Evidence of the importance of anterior lesions

Shifts of visual attention can be studied in adults and infants by cueing responses to a particular spatial location. Earlier studies have shown that by seven months of age normal infants show a similar pattern of facilitation and inhibition to a cued spatial location as adults. In this study we report data from infants with perinatal lesions that include or exclude the left anterior quadrant. Results indicate that infants with left anterior lesions do not show facilitation to a cued spatial location in this task. In contrast, infants with posterior lesions showed the same pattern of performance as healthy subjects. While these findings differ from those obtained with adults, they are consistent with previous studies of children with perinatal lesions, and with findings from ERP studies with normal infants.     

退步原来是向前

从契此的“手把青苗插满田,低头便见水中天,六根清净方为道,退步原来是向前”偈中,反映了退让并不是完全的消极,有时反而是一种积极的进取,从而揭示出丰富的人生哲理。     

苏辙“示疾而病”的禅学思想

＂多病则与学道者宜,多难则与学禅者宜＂,苏辙却因有＂喜汝因病悟,或免终身著＂的示疾而病的禅学思想。＂示疾而病＂的苏辙以维摩自喻,在深层意义上,是他借维摩诘而表现其忧以天下、以乐天下的人格理想。     

试论卫生与法律的关系

卫生是人类重要的社会实践活动。卫生也是保护人体健康的重要社会事业,需要法律的保护和导向。卫生法为卫生发展提供了良好的社会环境,并控制医药卫生无序、失控及异化带来的社会危害性,造福人类,促进经济发展和社会进步。     

Modeling signal features of escape response: effects of cessation conditioning in "learned helplessness" paradigm

Six experiments examined the effects of signaling the termination of inescapable shock (cessation conditioning) or shock-free periods (backward conditioning) on later escape deficits in the learned helplessness paradigm, using rats (Sprague-Dawley and Bantin-Kingman). A cessation signal prevented later performance deficits when highly variable inescapable shock durations were used during pretreatment. The inclusion of short minimum intertrial intervals during pretreatment did not alter the benefits of cessation conditioning but eliminated the protection afforded by a safety signal. The beneficial effects of both cessation and backward signals were eliminated when a single stimulus signaled shock termination and a shock-free period. Finally, a combination of cessation and backward signals was found to be most effective in immunizing against the effects of subsequent unsignaled, inescapable shock on later escape performance. These data suggest that cessation conditioning may be crucial to the prophylactic action of an escape response.     

Development of perceptual asymmetry for free viewing of chimeric stimuli

Free-viewing chimeric stimuli tasks have been used in a number of studies to assess perceptual asymmetries and draw inferences about hemispheric lateralization in children and adults. In order to determine whether perceptual asymmetries for nonverbal information are present in children, a free-viewing chimeric stimuli task was used in 63 normally developing 6- through 16-year-old children. Stimuli included affect (happy faces), gender, quantity, and shape. An overall left hemispace (LHS) advantage was present by 6 years of age. This LHS preference was more prominent by age 10 and then plateaued. No preference for shape was detected at any of the age ranges studied. These results suggest that perceptual asymmetries for visual stimuli develop during childhood and appear to reach a plateau by age 10. The observed specificity for certain types of nonverbal stimuli should be taken into account in future studies of perceptual asymmetry in both normal and neurologically impaired children.     

Culture in the context of intercultural negotiation.

This study explores culture's effect on behaviors and outcomes in intercultural negotiation and examines how those effects are moderated by role. Eighty U.S. and international students took part in a previously developed negotiation task (Pruitt, 1981) and completed Hui and Triandis's (1986) individualism‐collectivism (INDCOL) scale. Negotiation interactions were coded for information sharing, offers, and distributive tactics. Findings show that a negotiation dyad's collectivism is positively associated with higher joint profit. The effects of culture on both communication behaviors and joint outcomes, however, differ by role of the negotiator. In particular, seller collectivism has larger and more consistent effects on communication behavior and joint profit than buyer collectivism. Results support a ‘culture in context’ perspective of negotiation that takes into account negotiator qualities, contextual and structural features of the negotiation, and mediating processes in addition to cultural values.