Inhibition of the LH Surge by Restraint Stress in Cyclic Rats: Studies on the Role of GABAA and GABAB Receptors

There is evidence that stress can alter the activity in the brain of gamma-aminobutyricacid (GABA), a neurotransmitter that has been implicated in the regulation of LH secretion. In the present study the role of GABA in the restraint stress-induced inhibition of the LH surge was investigated in the intact cyclic rat. Intracerebroventricular (icv) administration of the GABAA receptor agonist muscimol (0.1, 0.5 or 1 μg) 5 min before the presumed onset of the pro-oestrous LH surge (at 0900 h) caused a dose dependent suppression of the surge. A single dose of the GABAB receptor agonist baclofen (1 μg; icv) injected at 0855 h postponed the onset of the LH surge, and repeated injections at 0855 and 1130 h suppressed the surge. These data indicate that GABA-ergic activity in the brain can inhibit the LH surge in the cyclic rat via GABAA and GABAB receptors. Pro-oestrous rats were subjected to 5 hrs of restraint starting at 0855 h. Pretreatment with the GABAA receptor antagonist bicuculine (1 μg; icv) at 0840, 0940 and 1040 h or pretreatment with the GABAB receptor antagonist phaclofen (10 μg; icv) at 0840 h were ineffective in preventing the restraint-induced inhibition of the LH surge. The results suggest that GABAA and GABAB receptors are not involved in the inhibitory effect of restraint stress on the LH surge.     

Effects of Acute Stress or Centrally Injected Interleukin-1beta on Neuropeptide Expression in the Immune System

Acute stress stimulates the expression and release of corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) from the hypothalamus, and the pro-opiomelanocortin products beta-endorphin and ACTH from the anterior pituitary. These neuropeptides are also expressed in immune tissues, and it has been proposed that they may modulate immune responses to stress through paracrine mechanisms. We subjected rats to restraint stress or central injection of interleukin (IL)-1beta to determine whether these acute stimuli can alter the expression of neuropeptides in the spleen and thymus. Restraint stress significantly increased the contents of all these neuropeptides in thymic, but not splenic, extracts. A single icv injection of IL-1beta increased contents of CRH, AVP, ACTH and beta-endorphin in the spleens of both sham-operated and adrenalectomised (ADX) rats. IL-1beta increased thymic contents of CRH and ACTH in sham-operated rats but these increases were not observed in ADX rats. These results suggest that the effects of IL-1beta on neuropeptide expression in the spleen are independent of glucocorticoids, whereas IL-1beta stimulation of neuropeptide expression in the thymus is dependent on circulating glucocorticoids. There were significant correlations between increases in CRH, ACTH and beta-endorphin in the spleen, and between CRH and ACTH in the thymus, consistent with the suggestion that IL-1beta-induced increases in ACTH and beta-endorphin may be mediated through CRH. These results provide evidence that stressors can directly influence neuropeptide expression in immune tissues. Thus stress may influence immune functions through paracrine mechanisms involving locally synthesised neuropeptides as well as through activation of the hypothalamo-pituitary-adrenal axis.     

Comparing learning environments in U.S. military officer education: a brief replication

A 2003 comparative study on learning environments at two military officer training sites was replicated using different methodology. Satisfaction with learning environment and with administrative inprocessing was higher at Fort Leavenworth than at Fort Dix. Most students expressed a preference for Fort Leavenworth. Satisfaction with institutional support and educational facilities appears to influence perceived satisfaction with a learning environment and with preference for training sites among senior military officers.     

Interpreting past religious discrimination today

Much of modern western law now presupposes opposition to discrimination based on race, religion, sex, national origin, and other factors. However, ancient religious Scriptures may have sanctioned certain types of discrimination. Whether those who are inclined to accept literal interpretations of their Scriptures will condone certain forms of discrimination could be evaluated to contrast the effects of modernization versus religious indoctrination on various kinds of prejudice.     

A discriminant analysis of Whissell's New Testament data: on the statistical trail of the author of Hebrews

Discriminant analyses of data on 6 dimensions from Whissell's analyses of 27 books of an English translation of the New Testament seem to support Clement of Alexandria's contention that Luke was involved in the authorship, but it is difficult after centuries to rule out definitively a few other contenders.     

First and Fourth Grade Boys' and Girls' Preferences For and Perceptions About Narrative and Expository Text

This investigation focused on elementary-aged (first and fourth grade) children's individual preferences for narrative and expository text and perceptions of what their same-aged peers would like to read. Preferences and perceptions of text were examined through the lenses of social constructivist and engaged reading theories. The overall purpose of this study was to examine elementary students' preferences for and perceptions about narrative and expository text. This study was a systematic replication and extension of Chapman, Filipenko, McTavish, and Shapiro's (2007) research in British Columbia with first graders. Two individually administered book preference (Open and Closed) tasks and interviews were administered to 84 students. Findings revealed gender and grade level profiles in terms of preferences, perceptions, and rationales for their book choices. As expected, both first and fourth grade boys demonstrated a strong preference for expository text, however, the fourth grade boys also showed a growing preference for narrative text as well. In contrast, both first and fourth grade girls demonstrated a strong preference for both narrative and expository text. For both boys and girls, book topic and pictures/illustrations were the two top categories that drew the children's interest and resulted in the most conversations. Results are discussed in light of implications for instruction, assessment, and future research.     

Differences in Paradox between Islam and Christianity: a statistical comparison

Historically Islam has been recognized as a religion that is logical. Christianity has long been recognized as having a number of beliefs or doctrines that could be described as paradoxical. Sixty-nine religious doctrines or beliefs were evaluated for paradoxical content and in terms of whether Islam and Christianity agreed or disagreed with respect to each doctrine or belief. It was hypothesized that disagreement between the two religions would be much more common with respect to paradoxical doctrines or beliefs. Nearly 90% of doctrinal agreement or disagreement could be traced to the paradoxical or non-paradoxical content of the beliefs evaluated. The relationship between agreement and paradox was very significant statistically. Implications for future Christian–Muslim dialogue are discussed.     

大学二年级学生人际宽恕与报复心理及其与抑郁的关系研究

采用沉思量表、报复动机量表、宽恕倾向量表、宽恕态度量表和流调中心用抑郁量表对236名大二学生进行问卷调查,综合探讨大学生人际宽恕和报复心理及其与抑郁的关系。研究发现:(1)男大学生的报复倾向显著高于女大学生。(2)宽恕倾向与报复倾向及对侵犯的沉思程度显著负相关。沉思程度和抑郁显著正相关。(3)沉思程度和宽恕倾向对抑郁分别具有显著的正向和负向的预测作用。(4)大学生的宽恕倾向和宽恕态度的相互作用以及宽恕倾向和报复倾向之间的交互作用对抑郁均没有显著预测作用。     

Dimensionality of subscales for emotional support in the Bosch Support Measure for survivors of domestic abuse

Items from the Emotional Support Subscale of the Bosch Support Measure were administered in a small survey of 56 formerly abused rural women in the midwestern USA. Maximum likelihood factor analyses were performed on a total of 21 items. A 5-factor solution appeared to produce the best results, but only 3 factors suggested viable subscales with Cronbach alphas greater than .80. Informal support networks in the rural areas studied here appeared to provide survivors of domestic violence with general emotional support to a greater extent than guidance on accessing professional resources and help.     

Premarital counseling: Approaches,objectives, content,and evaluation—a bibliography

A major problem for the premarital counselor is that the literature in the field is scattered throughout numerous journals and books representing several disciplines. Since counselors tend to subscribe to and read the literature from their own academic discipline, they may be unaware of what is being written elsewhere. This article contains a bibliography of what the authors consider to be the most relevant books and articles on premarital counseling published by the various disciplines. For the convenience of the reader, each listing is also coded as to its content.The authors express their appreciation to Charles R. Figley, Ph.D., Douglas H. Sprenkle, Ph.D., and Diane Spencer, M.S., for their assistance in the preparation of this paper. The valuable assistance of those contributors who notified the authors of their publications is gratefully acknowledged.