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BDNF serum levels in subjects developing or not post-traumatic stress disorder after trauma exposure
Francesco Angelucci Valerio Ricci Francesca Gelfo Giovanni Martinotti Marcella Brunetti Gianna Sepede Maria Signorelli Eugenio Aguglia Mauro Pettorruso Federica Vellante Massimo Di Giannantonio Carlo Caltagirone 《Brain and cognition》2014
Post-traumatic stress disorder (PTSD) is a syndrome resulting from exposure to a severe traumatic event that poses threatened death or injury and produces intense fear and helplessness. The neural structures implicated in PTSD development belong to the limbic system, an important region for emotional processing. Brain-derived neurotrophic factor (BDNF) is a neurotrophin that serves as survival factor for selected populations of central nervous system (CNS) neurons and plays a role in the limbic system by regulating synaptic plasticity, memory processes and behavior. Impaired BDNF production in the brain can lead to a variety of CNS dysfunctions including symptoms associated with PTSD. However, so far fewer studies have investigated this neurotrophin in patients with PTSD. Furthermore, given the multiple role of BDNF in various CNS disorders, it cannot be excluded that traumatic events per se may influence neurotrophin levels, without a direct association to the PTSD syndrome. 相似文献
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With the changing demographics in the United States, there is an increasing need for psychotherapy interventions that have been tailored for and empirically evaluated with culturally diverse groups. This article discusses the development and evaluation of a family-focused, culturally informed therapy for schizophrenia (CIT-S) that is currently being pilot tested at the University of Miami. Case examples of CIT-S with participating families are provided, along with a discussion of interesting and challenging cultural issues that we have encountered during the pilot phase of this treatment study. 相似文献
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Masip, et al. (2009) conducted a study in which observers had to make truth-lie judgments at the beginning, middle, or end of a series of videotaped statements. They found a decline in truth judgments over time and explained this finding in terms of information processing mode. Recently, Elaad (2010) challenged this explanation and contended that the decline could be a result of regression toward the mean. In the present paper, it is argued that because Masip, et al. took multiple Moment 1 judgments over time and then averaged across judgments, regression toward the mean was extremely unlikely. Furthermore, the decrease in truth judgments was found under several separate conditions; this cannot be explained by random fluctuations alone. Finally, Masip, et al.'s data were re-analyzed adjusting for the effects of regression toward the mean. The outcomes of these analyses were the same as those reported in the original article. 相似文献
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ResumenEl propósito de la presente investigación es desarrollar una jerarquía experimental que estudie las características más importantes del conflicto social en los procesos de influencia minoritaria. También se hace un análisis de los límites de la influencia latente minoritaria. Se defiende así la idea de que la influencia indirecta de las minorías reposa sobre una relación de naturaleza binaria no transitiva entre las posiciones minoritarias y las opiniones y actitudes objeto de influencia. Para ello se elaboró una serie de experimentos que combinan las siguientes variables, pertenencia categorial y presentatividad de la fuente minoritaria, en un diseño factorial 3 x 2. Los sujetos, 107 escolares (110 mujeres y 87 varones) fueron distribuidos en seis condiciones experimentales resultantes de la combinación de dos clases de variables: fuente de influencia perteneciente a un intragrupo, a un extragrupo, o a una minoría sin categorización social; fuente minoritaria representativa o no representativa. Los resultados subrayan la importancia del conflicto social en la producción de la influencia minoritaria y parecen confirmar la hipótesis de los límites en la influencia indirecta minoritaria. 相似文献
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RESUMENEn este artículo se analizan las implicaciones de la teoría de James con un siglo de perspectiva y, se realiza un amplio estudio de la noción de emoción y su significación psicológica y epistemológica. Se exponen los principios fundamentales de la Teoría de James-Lange, además de exponer la teoría de Canon que se enfrentaba a la Teoría de James-Lange, se recogen también, aquellas teorías que se sitúan en un punto intermedio de estas dos teorías. Finalmente se analiza en mayor profundidad la teoría de James en la actualidad y sus implicaciones epistemológicas. 相似文献
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The paper presents an epistemic logic with quantification over agents of knowledge and with a syntactical distinction between de re and de dicto occurrences of terms. Knowledge de dicto is characterized as ‘knowledge that’, and knowlegde de re as ‘knowledge of’. Transition semantics turns out to be an adequate tool to account for the distinctions introduced. 相似文献
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Starting from a proof-theoretic perspective, where meaning is determined by the inference rules governing logical operators, in this paper we primarily aim at developing a proof-theoretic alternative to the model-theoretic meaning-invariant logical pluralism discussed in Beall and Restall (Logical pluralism, Oxford University Press, Oxford, 2006). We will also outline how this framework can be easily extended to include a form of meaning-variant logical pluralism. In this respect, the framework developed in this paper—which we label two-level proof-theoretic pluralism—is much broader in scope than the one discussed in Beall and Restall’s book.
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T he babyface overgeneralization effect is perceiving that people whose facial features resemble those of children have childlike traits, and treating them accordingly. This experiment sought to replicate the US findings with a South‐European sample, to examine the impact of facial maturity on impressions of truthfulness, and to examine the influence of age on person perception. Three‐hundred and twenty‐four Spanish undergraduates were shown a photograph and had to rate it on a series of behavioural‐tendency and trait scales measuring honesty, truthfulness, strength, dominance, intelligence, naivety, and warmth. The photographs were babyfaced, intermediate, and mature faced computer‐manipulated versions of three pictures of the same individual at three different ages. Results indicate that the experimental manipulations significantly affected most of the dependent variables. Babyfaced individuals were perceived as the most truthful, and children as the most deceitful. However, when the deceit concerned a sexual abuse allegation, children were rated as the least deceitful. These results support the existence of (a) the babyface overgeneralization effect, (b) the stereotype that children are unreliable witnesses, and (c) the belief that children never lie about sexual abuse offenses. They also suggest that facial babyishness and age may be static perceived deception cues that may account for the demeanour bias found in nonverbal research on the detection of deceit. 相似文献