Consideration of the BDNF gene in relation to two phenotypes: hoarding and obesity

The gene coding for the brain derived neurotrophic factor (BDNF) has emerged as an interesting candidate for multiple brain and brain disorder-related phenomena. The primary aim of the present investigation was to consider the relationship between the BDNF Val66Met variant and two phenotypes: compulsive hoarding as a symptom dimension of obsessive-compulsive disorder (OCD), and body mass index (BMI). We examined the BDNF gene in a large (N=301) clinical sample of probands with OCD. Participants were classified as hoarding or nonhoarding using a strict, multimeasure grouping approach. Results revealed that the Val/Val genotype was linked with hoarding classification and more severe hoarding behaviors, as well as greater BMI levels. Hoarding status was also associated with greater BMI scores, with individuals in the hoarding group being far more likely to be classified as obese compared with the nonhoarding group. Our findings may provide a distinct avenue through which hoarding and BMI could be linked. These findings are suggestive of a complex gene, body weight, and psychopathology relationship wherein a primitive, survival "thrifty gene" strategy may be conserved and represented in a subgroup of humans manifesting severe hoarding symptoms.     

Keeping one's options open: The detrimental consequences of decision reversibility

People generally prefer to have the opportunity to revise their decisions. Surprisingly however, research has shown that keeping one's options open yields lower satisfaction with the decision outcome (Gilbert & Ebert, 2002). Two studies aimed to gain more insight into the detrimental consequences of decision reversibility and the cognitive processes underlying decision reversibility. Building upon literature on goal fulfillment we hypothesized and found in a first experiment that as long as decisions are still open to change, accessibility of decision-related constructs is increased compared to neutral constructs. A second experiment demonstrated that decision reversibility undermines working memory capacity. Moreover participants experienced higher regret after having made a reversible decision, an effect that was mediated by decreased working memory capacity. The study set implies that reversible decisions yield lower working memory capacity because people continue to think about the, still relevant, choice options. In the end this might increase dissatisfaction with the decision and regret.     

Stepping back to see the big picture: when obstacles elicit global processing

Can obstacles prompt people to look at the "big picture" and open up their minds? Do the cognitive effects of obstacles extend beyond the tasks with which they interfere? These questions were addressed in 6 studies involving both physical and nonphysical obstacles and different measures of global versus local processing styles. Perceptual scope increased after participants solved anagrams in the presence, rather than the absence, of an auditory obstacle (random words played in the background; Study 1), particularly among individuals low in volatility (i.e., those who are inclined to stay engaged and finish what they do; Study 4). It also increased immediately after participants encountered a physical obstacle while navigating a maze (Study 3A) and when compared with doing nothing (Study 3B). Conceptual scope increased after participants solved anagrams while hearing random numbers framed as an "obstacle to overcome" rather than a "distraction to ignore" (Study 2) and after participants navigated a maze with a physical obstacle, compared with a maze without a physical obstacle, but only when trait (Study 5) or state (Study 6) volatility was low. Results suggest that obstacles trigger an "if obstacle, then start global processing" response, primarily when people are inclined to stay engaged and finish ongoing activities. Implications for dealing with life's obstacles and related research are discussed.     

He just wants to play: how goals determine the influence of violent computer games on aggression

Generally, the accessibility of goal-related constructs is inhibited upon goal fulfillment. In line with this notion, the current studies explored whether violent computer games may reduce relative accessibility of aggression if the game involves the fulfillment of an aggressive goal. Specifically, in Study 1, participants who watched a trailer for a violent computer game that fulfilled the goal of venting anger showed less relative accessibility of aggression compared to participants who watched the trailer without goal fulfillment. In Study 2, actually playing a violent computer game to vent anger also decreased the relative accessibility of aggression compared to a control condition in which the game was played without such a goal. Lastly, in Study 3, the relative accessibility of aggression was reduced after playing a violent computer game for participants who reported a high general tendency to vent their anger.     

Two-Year Findings from a National Effectiveness Trial: Effectiveness of Behavioral and Non-Behavioral Parenting Programs

Long-term follow-up studies of selective parent training (PT) programs are scarce, particularly in the case of effectiveness trials conducted within regular care settings. This study evaluated the 2-year effects of 4 programs: Comet, Incredible Years, Cope, and Connect and differences in the rate of change among programs were investigated using Latent Growth Modeling (LGM). Participants were parents who had sought help at 30 local service sector units (e.g., child psychiatric clinics and social services centers) for major problems in managing their children’s externalizing behavior. Parents of 749 children (63 % boys) with moderate levels of externalizing behavior, aged 3–12, were randomized to one of the 4 PT programs. Assessments included parent-reported measures of child externalizing, hyperactivity and inattention, as well as parenting practices, sense of competence, and parents’ stress and depressive symptoms. At 2-year follow-up, there were no differences in any of the child outcomes among the programs. All programs had reduced externalizing behaviors with large effect sizes (d = 1.21 to d = 1.32), and negative parenting practices with moderate to large effect sizes (d = 0.49 to d = 0.83). LGM analyses showed that the 2 behavioral programs, Comet and Incredible Years, produced more rapid reductions in externalizing behavior during the course of the intervention than the non-behavioral program, Connect. Connect, however, was the only program where children continued to improve after the intervention. Overall, the results indicate that the 4 programs were equally effective in a clinical setting, despite differences in their theoretical origin.     

Parfit on fission

Derek Parfit famously defends a number of surprising views about “fission.” One is that, in such a scenario, it is indeterminate whether I have survived or not. Another is that the fission case shows that it does not matter, in itself, whether I survive or not. Most critics of the first view contend that fission makes me cease to exist. Most opponents of the second view contend that fission does not preserve everything that matters in ordinary survival. In this paper I shall provide a critique that does not rely on either of these contentions. There are other, interrelated reasons to reject Parfit’s defense of the two theses. In particular, the availability of the following view creates trouble for Parfit: I determinately survive fission, but it is indeterminate which fission product I am.     

How love and sex can influence recognition of faces and words: A processing model account

A link between romantic love and face recognition and sexual desire and verbal recognition is suggested. When in love, people typically focus on a long‐term perspective which enhances global perception, whereas when experiencing sexual encounters they focus on the present which enhances a perception of details. Because people automatically activate these processing styles when in love or sex, subtle reminders of love versus sex should suffice to change ways of perception. Global processing should further enhance face recognition, whereas local processing should enhance recognition of verbal information. In two studies participants were primed with concepts and thoughts of love versus sex. Compared to control groups, recognition of verbal material was enhanced after sex priming, whereas face recognition was enhanced after love priming. In Experiment 2 it was demonstrated that differences in global versus local perception mediated these effects. However, there was no indication for mood as a mediator. Copyright © 2009 John Wiley & Sons, Ltd.     

We all live in Germany but … Ingroup projection,group‐based emotions and prejudice against immigrants

Immigration, cultural diversity and integration are among the most central challenges for modern societies. Integration is often impeded by negative emotions and prejudices held by the majority members towards immigrants in a common society. Based on the ingroup projection model (Mummendey & Wenzel, 1999), we examined the impact of perceived relative ingroup prototypicality on intergroup emotions and prejudice. Additionally, we examined whether this impact is causal and explored the issue of causality in more detail contrasting a linear causal model with bi‐directional or reciprocal causality. Hypotheses were tested in a study with a two‐wave panel of majority members (N=1085) in Germany. We examined the proposed relations between relative ingroup prototypicality, intergroup emotions and prejudice and determined the causal direction of these relationships. Results support the predictive power of relative ingroup prototypicality on intergroup emotions and prejudice. Moreover, most causal relations between our measures are reciprocally causal. We discuss the implications of these findings for the general conception of prejudice and intergroup emotions. Copyright © 2009 John Wiley & Sons, Ltd.     

Mechanistic Constitution in Neurobiological Explanations

This paper discusses the constitution relation within the framework of the mechanistic approach to neurobiological explanation. It develops a regularity theory of constitution as an alternative to the manipulationist theory of constitution advocated by some of the proponents of the mechanistic approach. After the main problems of the manipulationist account of constitution have been reviewed, the regularity account is developed based on the notion of a minimal type relevance theory. A minimal type relevance theory expresses a minimally necessary condition of a given type that consists of a disjunction of minimally sufficient conditions of that type. Afterwards, the attained definition is successfully applied in an analysis of the logical structure of the explanation of spatial learning and memory in rats as a paradigm neurobiological explanation. The overall result is a more robust and more precise version of the mechanistic approach to neurobiological explanations.