Pupillary and heart rate reactivity in children with minimal brain dysfunction

This study attempted to replicate and extend previous findings on autonomic arousal and responsivity in children with diagnoses of minimal brain dysfunction (MBD). Pupil size, heart rate, skin conductance, and skin temperature were recorded from 32 MBD and 45 control children during a session that included presentation of visual stimuli, simple reaction time (RT), a cold pressor procedure, and rest periods. The MBD children were tested both off and on clinical dosages of stimulant drugs in a crossover design. Evidence of higher than normal arousal levels in the unmedicated MBD Ss was obtained from resting skin conductance and, more tenuously, from pupil size. Lower phasic responsivity in the MBD children was evidenced by slower RT, less cardiac deceleration to both light and RT stimuli, and smaller pupil dilation to the RT stimuli. Spontaneous pupillary constrictions during rest periods, presumably indicating drowsiness, were observed about equally in MBD and control children. Stimulant drugs raised arousal levels but did not reverse the responsivity deficits. The lower phasic reactivity in the MBD group and the effects of stimulant drugs on arousal indices confirm earlier reports. The finding of higher arousal in drug-free MBD children is incompatible with the low arousal hypothesis of MBD but is consistent with a previous report of the effects of a stimulating environment on these children.This work was supported in part by a grant from the Ittleson Family Foundation. The authors thank Frank Abate for technical assistance.     

Naming of object-drawings by dyslexic and other learning disabled children

On the Oldfield-Wingfield Picture-Naming Test, sensitive to subtle chronic dysphasia in adults, dyslexic children name fewer pictures correctly. Even when correct on words with less than 30 per million frequency of occurrence, they perform more slowly than do nondyslexic subjects suffering from minimal brain dysfunction (MBD) or normal controls. However, there is no evidence for “perceptual impairment” underlying dyslexic subjects' low scores and prolonged latencies, as the distribution of their errors is similar to that of normal children. Rather it is the nondyslexic MBD group which produces a high percentage of wrong names, suggestive of mistaking the pictured stimuli for other, visually similar, objects.     

Atypical brain responses to sounds in children with specific language and reading impairments

This study tested if children with specific language impairment (SLI) or children with specific reading disability (SRD) have abnormal brain responses to sounds. We tested 6‐ to 12‐year‐old children with SLI (N =19), children with SRD (N =55), and age‐matched controls (N =36) for their passive auditory event‐related potentials (ERPs) to tones, rapid tones, vowels and consonant‐vowels. Thirty‐eight percent of the children with SLI or SRD had less typical passive auditory ERPs in the N1–P2 window to sounds in general, rather than to tones, rapid tones, vowels or consonant‐vowels specifically. The ERPs of these children were significantly ‘flatter’ in the N1–P2 region than normal. All the children with flatter ERPs in the N1–P2 region had poor non‐word reading. A subgroup of these poor non‐word readers also had poor non‐word repetition. These findings support the hypothesis that impaired auditory processing is a causal risk factor for both SLI and SRD.     

Concurrent Verbal and Emotion Laterality Effects Exhibited by Normally Achieving and Learning Disabled Children

This study assessed both left- and right-hemisphere functions simultaneously when two-syllable words differing only in the initial stop consonant and spoken in different emotional tones were paired dichotically. Seventy-two right-handed normally achieving children, 12 boys and 12 girls at each of grades 1, 3, and 5, were instructed to detect either the presence of a specific word or of a specific emotion. In addition, 30 right-handed learning disabled (LD) children (age-matched to the normal controls) were assessed to determine whether LD children distribute verbal and nonverbal functions to different hemispheres. Results indicated that although both control and LD children demonstrated an overall REA for word stimuli and an LEA for emotional stimuli, and that emotional stimuli were easier to process than word stimuli, LD children were less accurate in processing both types of stimuli than their control counterparts. ‘Complementary specialization,’ as assessed through distribution of laterality effects, was found to be greater for control children than for LD children. However, the lack of consistency in complementary specialization found among the three developmental grade levels may be indicative that independent brain mechanisms underlying verbal and emotional processing have yet to be fully established in children. Further, in contrast to adult findings, a larger LEA was obtained for the emotion ‘happy’ than for the emotion ‘sad.’ It was concluded that whereas independent hemisphere processing for words and emotions is somewhat prevalent for control children, LD children might not be as strongly lateralized for opposite hemisphere processing of these functions.     

Cardiovascular generalization and differentiation: The relationship between heart rate and blood pressure

The present study was designed to study generalization and differentiation and to check the relation between heart rate and blood pressure in cardiovascular conditioning. Five naive mongrel dogs were presented with 10 sec 1000 cps tone regularly reinforced with 0.5-sec shock to a left foreleg. Four other 10-sec tones (600, 800, 1200, 1400 cps), never reinforced, were administered in a randomized and counterbalanced fashion using a differential reinforcing technique. The response measures were heart rate and three indices of blood pressure,i.e., systolic, diastolic, and pulse pressures.“Initial response” of heart rate showed rapid tachycardia to all tones, with no generalization and differentiation among five tones.“Terminal response” clearly indicated generalization gradients that tachycardia to 800 and 1200 cps tones were higher than those to 600 and 1400 cps tones, respectively. Some differences were noted among systolic, diastolic, and pulse pressures, with pulse pressure showing a trend of generalization and differentiation in the“initial response.” No statistical difference, however, was obtained in blood pressure scores. Beat-by-beat analyses of correlations between heart rate and diastolic blood pressure showed that the correlations successively decreased during the“terminal response.” Overall correlations between heart rate and three indices of blood pressure were obtained, with the highest correlation between heart rate and pulse pressure. Considering the above results in relation to the classical conditioning theory, it was tentatively concluded that“initial response” includes non-conditional factors, while“terminal response” reflects mainly a true conditional response, particularly, at a long CS-US interval. This interpretation leads to the hypothesis that conditional response with a short CS-US interval may attain better conditioning scores in terms of the summation effect between a non-conditional factor and a true conditional factor.     

多动症儿童与认知事件相关电位的实验研究

本研究通过对29名多动症(MBD)儿童与正常儿童认知事件相关电位各成份的比较,结果发现多动症组与正常儿童组在反映大脑认知功能P300潜伏期有明显的差异,从而说明P300可以作为检测多动症儿童的参考性的客观指标。     

多动症儿童的智力水平、行为与认知事件相关电位的研究

通过对多动症 (MBD)儿童的智力、行为和认知事件相关电位的分析研究,发现多动症儿童的智力水平正常但均数都低于正常儿童,行为问题的检出率和行为量表指数高于一般正常儿童,反映大脑认知功能的事件相关电位的N2、P3的潜伏期较之正常儿童组均延长,且差异均达到显著性水平。     

Developmental changes in application of the majority rule in group decisions

This study examined age-related changes in the child's application of the principle of majority rule in group decisions. Following a problem posed by Moessinger (1981), we enquired whether children routinely apply the majority rule when the majority consists of a shifting (variable) set of members across decisions, and alternate between majority and minority when the majority and minority is fixed, i.e. consists of the same individuals each time. In Geneva, Moessinger found that 8-year-olds failed to discriminate between fixed and shifting majorities, while most 13-year-olds (75 per cent) did so. An altered replication was conducted in Australia modifying Moessinger's procedure to control for extraneous variables such as ‘set’ and the need for variety in choice. It was found that on the task 7 per cent of 8-year-olds, 20 per cent of 10-year-olds, 32 per cent of 12-year-olds, and 39 per cent of 14-year-olds discriminated on a behavioural criterion between fixed and shifting majorities. Ten per cent of 8-year-olds, 40 per cent of 10-year-olds, 52 per cent of 12-year-olds, and 55 per cent of 14-year-olds made the discrimination on Moessinger's cognitive ‘reason’ criterion. The results show that development of the conceptual distinction between fixed and shifting majorities is gradual and continuous.     

Concurrent task performance enhances low-level visuomotor learning

Visuomotor association learning involves learning to make a motor response to an arbitrary visual stimulus. This learning is essential for visual search and discrimination performance and is reliant upon a well-defined neural circuit in the brain that includes the prefrontal cortex and the hippocampal formation. In the present study, we investigated the possible role of attentional processes during such learning using dual-task interference. A motor, verbal, or perceptual concurrent task was performed during the learning/training block of a simple visual discrimination task. Contrary to expectation, the dual-task groups showed improved learning and learning-dependent performance compared with untrained control and non-dual-task trained groups. A second experiment revealed that this effect did not appear to be due to increased arousal level; the inclusion of alerting tones during learning did not result in facilitation. These findings suggest that the engagement of attention, but not arousal, during the acquisition of a visuomotor association can facilitate this learning and its expression.     

Evidence for early arousal‐based differentiation of emotions in children’s musical production

Accurate perception and production of emotional states is important for successful social interactions across the lifespan. Previous research has shown that when identifying emotion in faces, preschool children are more likely to confuse emotions that share valence, but differ in arousal (e.g. sadness and anger) than emotions that share arousal, but differ on valence (e.g. anger and joy). Here, we examined the influence of valence and arousal on children's production of emotion in music. Three‐, 5‐ and 7‐year‐old children recruited from the greater Hamilton area (N = 74) ‘performed’ music to produce emotions using a self‐pacing paradigm, in which participants controlled the onset and offset of each chord in a musical sequence by repeatedly pressing and lifting the same key on a MIDI piano. Key press velocity controlled the loudness of each chord. Results showed that (a) differentiation of emotions by 5‐year‐old children was mainly driven by arousal of the target emotion, with differentiation based on both valence and arousal at 7 years and (b) tempo and loudness were used to differentiate emotions earlier in development than articulation. The results indicate that the developmental trajectory of emotion understanding in music may differ from the developmental trajectory in other domains.     

Exploration of perceptual and motor inhibition in children with traumatic brain injury

Perceptual and motor inhibition were examined using conflict resolution tasks for 12 children with traumatic brain injury and 24 matched controls. Direct comparisons of inhibition performances between the two groups showed a specific and disproportionate impairment of motor inhibition (compared with perceptual inhibition) for the children with traumatic brain injury, which suggests that inhibition processes might be differentially impaired in children after traumatic brain injury.     

Subjectively different emotional schematic faces not automatically discriminated from the brain’s bioelectrical responses

The present study investigates how the brain automatically discriminates emotional schematic faces, as indicated by the mismatch responses, and how reliable these brain responses are. Thirty-three healthy volunteers participated in the vMMN EEG experiment with four experimental sets differing from each other by the type of standard (object with scrambled face features) and the type of deviants (Angry, Happy and Neutral schematic faces) presented. Conscious subjective evaluations of valence, arousal and attention catching of the same stimuli showed clear differentiation of emotional expressions. Deviant faces elicited rather similar vMMN at frontal and occipital sites. Bayesian analyses suggest that vMMN does not differ between angry and happy faces. Neutral faces, however, did not yield statistically significant vMMN at occipital leads. Pearson’s correlation and intra-class correlation analyses showed that the brain’s reactions to the stimuli were highly stable within individuals across the experimental sets, whereas the mismatch responses were much more variable.     

Auditory ERP in extremely premature 5-year-old children

The aim of this research was to test the hypothesis of a functional impairment in the automatic detection of deviant tones in 141 children born after 25 to 28 weeks of gestational age, as compared to 45 age-matched full-term control children. All of them were assessed at age 5 years 9 months and instructed to listen passively to two different pure tones (1000 vs 1200 Hz; 20 vs 80%) counterbalanced between ears. Rarity was thus defined by specific ear by tone combinations. The temporal N100 showed a clear contralateral functional organization of the central auditory pathway, especially for the left ear, but without group difference. By contrast, in full-term controls but not in premature children, the central N200 was specifically increased over frontal leads to rare stimuli as compared to frequent. Premature children demonstrated a lack of brain response when more complex processing integrating different informations was required.     

Reaction times and dyslexia

Five groups of children, including two groups of dyslexics (aged 15 and 11 years), were tested on simple reaction, selective choice reaction, and lexical decision tasks. In simple reactions to a pure tone, the dyslexic children responded as quickly as their chronological age controls and significantly faster than their reading age controls. In selective choice reactions to pure tones, the dyslexic children were significantly impaired compared with their chronological age controls and no faster than their reading age controls. This speed impairment obtained even though a selective choice reaction task has only one positive response. In “by-item” analyses of lexical decisions to spoken words, the dyslexic children were significantly impaired compared even with their reading age controls. The pattern of results suggests that at least two factors contribute to slowness of dyslexic children: a general deficit reflected in slower stimulus classification speed and a linguistic deficit reflected in slower lexical access speed.     

Cognitive predictors of parent-rated inattention in very preterm children: The role of working memory and processing speed

Inattention is one of the most common neurobehavioral problems following very preterm birth. Attention problems can persist into adulthood and are associated with negative socio-emotional and educational outcomes. This study aimed to determine whether the cognitive processes associated with inattention differ between term-born and very preterm children. Sixty-five children born very preterm (<33+0 weeks’ gestation) aged 8–11 years were recruited alongside 48 term-born controls (?37 20 +0 weeks’ gestation). Both groups included children with a wide spectrum of parent-rated inattention (above average attention to severe inattention) measured as a continuous dimension using the Strengths and Weaknesses of ADHD and Normal-Behavior (SWAN) scale. The children completed tests to assess basic cognitive processes and executive function. A hierarchical multiple regression analysis was implemented to assess which neurocognitive processes explained variance in parent-rated inattention and whether these differed between preterm and term-born children. In both groups, poorer verbal and visuospatial short-term memory and poorer visuospatial working memory independently explained variance in parent-rated inattention. Slower motor processing speed explained variance in inattention among very preterm children only. The cognitive mechanisms associated with parent-rated inattention were predominantly overlapping between groups, but relationships between motor processing speed and inattention were unique to very preterm children. These associations may reflect risk factors for inattention in term and very preterm children. Future research should assess the efficacy of these cognitive processes as potential targets for intervention     

Perceiving arousal and valence in facial expressions: Differences between children and adults

Arousal and valence have long been studied as the two primary dimensions for the perception of emotional stimuli such as facial expressions. Prior correlational studies that tested emotion perception along these dimensions found broad similarities between adults and children. However, few studies looked for direct differences between children and adults in these dimensions beyond correlation. We tested 9-year-old children and adults on rating positive and negative facial stimuli based on emotional arousal and valence. Despite high significant correlations between children’s and adults’ ratings, our findings also showed significant differences between children and adults in terms of rating values: Children rated all expressions as significantly more positive than adults in valence. Children also rated positive emotions as more arousing than adults. Our results show that although perception of facial emotions along arousal and valence follows similar patterns in children and adults, some differences in ratings persist, and vary by emotion type.     

Identifying play characteristics of pre-school children with developmental coordination disorder via parental questionnaires

Motor coordination deficits that characterize children with Developmental Coordination Disorder (DCD) affect their quality of participation. The aim of the current study was to identify play characteristics of young children with DCD, compared to those of children with typical development in three dimensions: activity and participation, environmental factors and children’s impairments.MethodSixty-four children, aged four to six years, participated. Thirty were diagnosed as having DCD; the remaining 34 children were age, gender and socioeconomic level matched controls with typical development. The children were evaluated by the M-ABC. In addition, their parents completed a demographic questionnaire, the Children’s Activity Scale for Parents (CHAS-P), the Children’s Leisure Assessment Scale for preschoolers (CLASS-Pre), and My Child’s Play Questionnaire (MCP).ResultsChildren with DCD performed significantly poorer in each of the four play activity and participation domains: variety, frequency, sociability, and preference (CLASS-Pre). Furthermore, their environmental characteristics were significantly different (MCP). They displayed significantly inferior performance (impairments) in interpersonal interaction and executive functioning during play, in comparison to controls (MCP). Moreover, the children’s motor and executive control as reflected in their daily function as well as their activities of daily living (ADL) performance level, contributed to the prediction of their global play participation.DiscussionThe results indicate that the use of both the CLASS-Pre and the MCP questionnaires enables the identification of unique play characteristics of pre-school children with DCD via parents’ reports. A better insight into these characteristics may contribute to theoretical knowledge and clinical practice to improve the children’s daily participation.     

Precision and accuracy in the reproduction of simple tone sequences

In four experiments we investigated the precision and accuracy with which amateur musicians are able to reproduce sequences of tones varied only temporally, so as to have tone and rest durations constant over sequences, and the tempo varied over the musically meaningful range of 5-0.5 tones per second. Experiments 1 and 2 supported the hypothesis of attentional bias toward having the attack moments, rather than the departure moments, precisely times. Experiment 3 corroborated the hypothesis that inaccurate timing of short interattack intervals is manifested in a lengthening of rests, rather than tones, as a result of larger motor activity during the reproduction of rests. Experiment 4 gave some support to the hypothesis that the shortening of long interattack intervals is due to mnemonic constraints affecting the rests rather than the tones. Both theoretical and practical consequences of the various findings, particularly with respect to timing in musical performance, are discussed.     

Effects of stimulus differentiation training upon hypotheses,strategies, and stereotypes in discrimination learning among kindergarten children

Two groups of kindergarten children received stimulus differentiation training either with feedback (experimental Ss) or without (controls), prior to presentation of a series of discrimination-learning problems using blanktrial probes. Results were as follows: Performance of both groups was virtually perfect during differentiation training (less than one error per 1000 trials). In transfer, however, experimental Ss solved more problems, generated more consistent Ss during blank-trial probes, manifested fewer response sets, were more likely to abandon a disconfirmed H, sampled more locally consistent Ss following errors, and retained a confirmed H more frequently than control Ss. Experimental Ss also manifested strategy Sys (hypothesis sampling systems) predominately, while controls generated only stereotypes. Findings were discussed in relation to theoretical perspectives derived from Piagetian theory and developmental learning theory.     

Do Children Behave Better When Parents’ Emotion Coaching Practices are Stimulated? A Micro-Trial Study

The links between parents’ emotion regulation practices and children’s behavioral outcomes are well established. The aim of the current study designed as a randomized micro-trial was to test experimentally if and to what extent stimulating parents’ emotion coaching practices improves preschoolers’ behavioral outcomes, i.e. positive affect, irritability, non-compliance, persistence and enthusiasm. In line with this objective, the emotion coaching practices of parents of 4-to-5-year-old children were stimulated in a brief 15-min lab session. Immediately afterwards, parents and children were observed during a free-play session and frustration laboratory tasks designed to elicit negative emotions in children. The results indicated that, compared to the control group, parents whose emotion coaching practices had been stimulated displayed higher positive affect and were more emotionally sensitive during free play. Positive behaviors persisted in frustration tasks; parents were more behaviorally and emotionally responsive towards their children. In turn, children of these parents displayed higher persistence and enthusiasm but only when they had to deal with negative emotional arousal during frustration tasks. Mediation analyses also confirmed that the influence of the stimulation of parents’ emotion coaching practices on children’s outcomes, i.e. persistence and enthusiasm, was mediated by the parents’ behavior.