诱导排尿反射对急性酒精性意识障碍患者催醒作用的研究

为了观察以呋塞米注射液诱导排尿反射对急性酒精性意识障碍患者促醒的作用,将30例急性重度酒精中毒患者纳入观察,随机分为2组,每组15例.两组患者均予补液,营养支持,纠正水电解质、酸碱平衡等对症处理.对照组予注射用纳洛酮2mg,加入5％葡萄糖溶液中静滴,纳洛酮日总用量不超过4.0mg.观察组在对照组基础上,加用呋塞米注射液20mg静脉推注,1次/日.对照组治疗后平均苏醒时间为1.85h±0.26h,观察组治疗后平均苏醒时间为1.28h±0.22h,经t检验,t=6.481 7,P＜0.01,提示观察组疗效优于对照组.笔者认为,以呋塞米注射液诱导排尿反射对急性酒精性意识障碍患者有较好的促醒作用,不仅与促进酒精代谢有关,兴奋觉醒中枢亦是其可能的机制.     

妇科恶性肿瘤合并静脉血栓栓塞的研究进展

静脉血栓栓塞(venous thromboembolism,VTE)是妇科恶性肿瘤的常见并发症之一,与患者的病死率升高密切相关。患者自身状态、肿瘤的类型、分期及手术、放化疗等治疗手段均可构成VTE的危险因素。但目前尚缺乏专门针对妇科恶性肿瘤合并VTE的临床实验数据以及预防和诊治指南。     

手术室护士术前访视存在的问题及对策

通过对手术患者实施术前访视工作中存在的问题进行分析,主要问题有:护理人员对访视重要性认识不足、缺乏知识、缺乏沟通技巧、人力资源不足及患者自身问题等.认为制定相关措施、贯彻落实术前访视制度、提高护士的业务水平、增进护患交流可提高术前访视质量,使患者以最佳状态接受手术.     

妇科恶性肿瘤合并静脉血栓栓塞的研究进展

静脉血栓栓塞(venous thromboembolism,VTE)是妇科恶性肿瘤的常见并发症之一,与患者的病死率升高密切相关.患者自身状态、肿瘤的类型、分期及手术、放化疗等治疗手段均可构成VTE的危险因素.但目前尚缺乏专门针对妇科恶性肿瘤合并VTE的临床实验数据以及预防和诊治指南.     

机器学习在抑郁症领域的应用

抑郁症患者疾病意识的不足以及早期筛查方法的缺乏导致患者在被诊断时大多已发展至重性抑郁障碍。为改善现状, 近年来机器学习被逐渐应用到抑郁症的早期预测、早期识别、辅助诊断和治疗决策中。在应用中, 机器学习模型准确性的影响因素包括样本集种类及规模、特征工程、算法类型等。建议未来将机器学习进一步融入医疗健康系统及移动应用程序等, 不断优化机器学习模型, 通过充分挖掘患者健康数据来改善抑郁症的预防、识别、诊断和治疗等相关问题。     

持续性植物状态若干问题的探讨

明确意识的含义及意识障碍的分类是分析持续性植物状态的前提。根据多年临床经验对持续性植物状态的定义、评分标准、诊断与鉴别诊断进行深入割析。植物状态的研究取得相当进展,但从诊断、评分到治疗手段仍面临诸多困惑,而神经干细胞移植和神经电刺激术是未来希望所在。     

脑功能成像在催眠状态中的研究进展

催眠是一种特殊的意识状态。本文从意识状态、疼痛及精神病理现象三个方面对脑功能成像在催眠状态中的研究进展进行了回顾,并对脑功能成像技术进行了比较。提出国内可以借鉴相应的方法来研究中国气功。     

主体意识不等于自我意识

首先,自我意识与主体意识在产生的时间上有先后之分。自我意识是人对自身的状态以及自身与外界关系的意识,即以自身为对象的意识。主体意识则是人自立为主体并对于自身的主体地位、主体能力、主体价值的一种自觉意识,是主体自主性和能动性的观念表现。从时间的序列看,主体意识是后     

意识状态改变的心理生理学理论与实证研究

从“意识状态”解释人类意识的本质是当前意识心理学研究的一个重要取向。研究意识状态改变(ASC)的物质生理基础具有十分突出的理论和临床实践意义。意识状态改变可以分为自发、物理和生理原因、心理方式和疾病引起这样四个方面,不同类型的意识状态改变可以从激活、意识域、自我觉察和感觉振荡四个维度进行综合归类和分析。不仅脑结构功能状态、脑动力的暂时变化、神经化学过程和新陈代谢过程等因素影响着人的意识经验改变状态,而且环境变化、心理活动和自我控制及技巧也可以暂时改变人的意识功能状态。     

佛教信众环保意识与行为现状问卷分析

"佛教信众生态环保意识与行为现状"问卷调查发现,大陆佛教信众生态环保意识和行为尚存在生态环保知识不扎实、生态环保意愿不足、日常生态环保行为有待深化、生态实践活动单一、生态环保宣传缺乏自觉意识等局限。引导佛教信众生态环保意识与行为应从政府的规范、引导与组织,社会生态文化氛围的营造,信众自身的努力和积极参与等方面进行。     

植物状态的残存脑功能和意识研究

综述了有关植物状态患者对外加刺激脑反应的功能成像研究文献,着重讨论了研究发现的非典型激活的临床价值以及植物状态患者是否存在意识的功能脑成像证据。     

Establishing consciousness in non-communicative patients: a modern-day version of the Turing test

In a recent study of a patient in a persistent vegetative state, [Owen, A. M., Coleman, M. R., Boly, M., Davis, M. H., Laureys, S., & Pickard, J. D. (2006). Detecting awareness in the vegetative state. Science, 313, 1402] claimed that they had demonstrated the presence of consciousness in this patient. This bold conclusion was based on the isomorphy between brain activity in this patient and a set of conscious control subjects, obtained in various imagery tasks. However, establishing consciousness in unresponsive patients is fraught with methodological and conceptual difficulties. The aim of this paper is to demonstrate that the current debate surrounding consciousness in VS patients has parallels in the artificial intelligence (AI) debate as to whether machines can think. Basically, (Owen et al., 2006) used a method analogous to the Turing test to reveal the presence of consciousness, whereas their adversaries adopted a line of reasoning akin to Searle's Chinese room argument. Highlighting the correspondence between these two debates can help to clarify the issues surrounding consciousness in non-communicative agents.     

Possibilities and limits of mind-reading: A neurophilosophical perspective

Access to other minds once presupposed other individuals’ expressions and narrations. Today, several methods have been developed which can measure brain states relevant for assessments of mental states without 1st person overt external behavior or speech. Functional magnetic resonance imaging and trace conditioning are used clinically to identify patterns of activity in the brain that suggest the presence of consciousness in people suffering from severe consciousness disorders and methods to communicate cerebrally with patients who are motorically unable to communicate. The techniques are also used non-clinically to access subjective awareness in adults and infants. In this article we inspect technical and theoretical limits on brain–machine interface access to other minds. We argue that these techniques hold promises of important medical breakthroughs, open up new vistas of communication, and of understanding the infant mind. Yet they also give rise to ethical concerns, notably misuse as a consequence of hypes and misinterpretations.     

Self-consciousness in non-communicative patients

The clinical and para-clinical examination of residual self-consciousness in non-communicative severely brain damaged patients (i.e., coma, vegetative state and minimally conscious state) remains exceptionally challenging. Passive presentation of the patient's own name and own face are known to be effective attention-grabbing stimuli when clinically assessing consciousness at the patient's bedside. Event-related potential and functional neuroimaging studies using such self-referential stimuli are currently being used to disentangle the cognitive hierarchy of self-processing. We here review neuropsychological, neuropathological, electrophysiological and neuroimaging studies using the own name and own face paradigm obtained in conscious waking, sleep, pharmacological coma, pathological coma and related disorders of consciousness. Based on these results we discuss what we currently do and do not know about the functional significance of the neural network involved in "automatic" and "conscious" self-referential processing.     

意识和无意识活动的脑区能态理论

本文在脑的四个功能系统学说的基础上,提出脑区能态理论,研究有意识、无意识和潜意识。讨论有意识、无意识、潜意识的脑机制,指出有意识、无意识、潜意识的统一性。     

Prefrontal lesion evidence against higher-order theories of consciousness

According to higher-order theories of consciousness, a mental state is conscious only when represented by another mental state. Higher-order theories must predict there to be some brain areas (or networks of areas) such that, because they produce (the right kind of) higher-order states, the disabling of them brings about deficits in consciousness. It is commonly thought that the prefrontal cortex produces these kinds of higher-order states. In this paper, I first argue that this is likely correct, meaning that, if some higher-order theory is true, prefrontal lesions should produce dramatic deficits in visual consciousness. I then survey prefrontal lesion data, looking for evidence of such deficits. I argue that no such deficits are to be found, and that this presents a compelling case against higher-order theories.     

意识:大脑整体运动态

简要叙述有关意识问题的不同理论观点,同时从一个全新的角度提出对意识内涵的理解:意识是大脑整体运动态,是能够与环境相互作用形成心理现象的大脑"运动态".意识是大脑运动的固有属性,大脑运动的本质功能就是产生意识.意识随着大脑的进化而进化,同时又是大脑进化的动因.     

Color, consciousness, and the isomorphism constraint

The relations among consciousness, brain behavior, and scientific explanation are explored in the domain of color perception. Current scientific knowledge about color similarity, color composition, dimensional structure, unique colors, and color categories is used to assess Locke's "inverted spectrum argument" about the undetectability of color transformations. A symmetry analysis of color space shows that the literal interpretation of this argument--reversing the experience of a rainbow--would not work. Three other color to color transformations might work, however, depending on the relevance of certain color categories. The approach is then generalized to examine behavioral detection of arbitrary differences in color experiences, leading to the formulation of a principled distinction, called the "isomorphism constraint," between what can and cannot be determined about the nature of color experience by objective behavioral means. Finally, the prospects for achieving a biologically based explanation of color experience below the level of isomorphism are considered in light of the limitations of behavioral methods. Within-subject designs using biological interventions hold the greatest promise for scientific progress on consciousness, but objective knowledge of another person's experience appears impossible. The implications of these arguments for functionalism are discussed.     

Coherence,Brain Evolution,and the Unity of Consciousness: The evolution of Planetary Consciousness in the Light of Brain Coherence Research

The law of coherence helps us understand the physical force behind the increasing complexity of the evolutionary process, from quanta, to cells, to self-awareness and collective consciousness. The coherent electromagnetic field is the inner glue of every system, the “intelligent” energy–information communication that assures a cooperative and synergic behavior to all the components of the system, as a whole, allowing harmonious evolution and unity of consciousness. Neuropsychological experiments show that the different brain areas communicate with more or less coherence according to different states of consciousness: high values are correlated with states of psychophysical integrity and well-being, whereas low values with states of conflict and depression. If we expand isomorphically these brain discoveries, we will have four main general states of coherence: from disgregation to unity, which represents an important element, in the General System Theory, to differentiate between inanimate and animate system, and to understand how billions cells become a single living organism, and then how billions of human beings could eventually generate planetary consciousness. In this light the resolution of the global ecosystem crisis implicates human transformation from a low to a highly coherent state of consciousness. The key to the entire process seems to be the coherent nature of consciousness.