应用烧伤整形外科技术治疗大面积皮肤撕脱伤

探讨大面积皮肤撕脱伤的治疗方法。分析总结大面积皮肤撕脱伤及合并损伤17例,根据伤情综合应用清创撕脱皮肤缝合、带蒂真皮下血管网皮瓣回植、撕脱皮肤反取皮回植、组织瓣转移修复、游离皮片移植、头皮取皮术、异体／异种皮移植、创面持续负压吸引VSD等治疗方法,观察创面修复、肢体外观及功能恢复情况。结果17例患者经综合治疗后创面均愈合。功能部位均予全层皮片或皮瓣修复;19处创面有深部组织外露,予皮瓣或肌瓣修复;随访6个月～3年,所有肢体功能良好。根据皮肤软组织损伤情况而综合运用多种烧伤整形外科技术修复大面积撕脱伤可缩短疗程,并最大可能保留受伤区域的功能与外观,改善患者生活质量。     

封闭式负压引流技术在慢性创面愈合中的应用进展及启示

医学与医疗技术的发展,改善了民生,促进了生命,见证了哲学真理。在现代医疗技术中,封闭式负压引流技术是慢性创面愈合中的一项重要辅助技术,它具有减少伤口细菌数量、改善局部血循环、促进伤口快速愈合等优点。这项技术的临床价值,已在慢性创面如压疮、烧伤、糖尿病足、下肢静脉曲张溃疡等的临床应用中日益显现。国内外学者不断的探索与研究,促进了慢性创面愈合技术的矛盾运动与技术成熟,也给患者带来了福音。封闭式负压引流技术的发展,印证了实践论与认识论哲学,蕴涵了矛盾学说与辩证智慧。     

从技术创新看负压封闭引流技术的发展

负压封闭引流技术(vacuum sealing drainage,VSD)是近几年来发展起来的一项新的创口引流技术,其操作方便,应用简单,在临床各个科室得到广泛应用和发展,作者介绍了这一新的引流技术的发展历史、技术原理及临床应用情况.并对负压封闭引流技术的创新特点和创新方法进行了简要论述及展望.     

从技术创新看负压封闭引流技术的发展

负压封闭引流技术(vacuumsealing drainage,VSD)是近几年来发展起来的一项新的创口引流技术,其操作方便,应用简单,在临床各个科室得到广泛应用和发展,作者介绍了这一新的引流技术的发展历史、技术原理及临床应用情况。并对负压封闭引流技术的创新特点和创新方法进行了简要论述及展望。     

辽宁省中西医结合糖尿病足治疗中心

大连医科大学附属第二医院北院区中西医结合科以糖尿病足、慢性创面、慢性骨髓炎、静脉性溃疡的治疗与修复为专科特色。     

烧伤治疗--仍需走出困境

以促进创面干燥,再行切痂植皮为局部治疗特点的外科技术,仍是烧伤治疗的主流,促使创面干燥是渗出的对症处理,切痂植皮的实质是将烧伤创面变为刀伤创面,然后再修补刀伤创面。显然,烧伤外科的治疗观已撤开了烧伤的病理变化和机体的免疫力,再生力,孤立地看待烧伤创面,认识上形而上学,治疗上一刀切,没有从根本上解决创面的疼痛,进行性坏死、感染和瘢痕愈合四大难题,相反,干燥切痂植皮技术的实施又是建立在病人痛苦之上的,     

辩证认识处理烧伤创面

人体是对立统一的有机整体,烧伤后皮肤局部形态结构和功能发生改变,进而引发局部与全身病理生理变化,烧伤创面处理贯穿于烧伤治疗的全过程。辩证认识和正确处理烧伤创面,提高烧伤治愈率;并将皮肤组织工程、整形外科等先进的技术手段和方法应用于烧伤创面的修复治疗,降低烧伤患者晚期畸形发生率,最大程度地让患者重返社会,恢复正常的生活和工作,这是现代烧伤治疗的目标。     

心肾贫血综合征的系统思维

心肾贫血综合征在慢性肾脏疾病患者和慢性心衰患者中大有人在,并日益受到医生重视,对其的正确认识及治疗直接影响患者的疾病预后,因此我们深入认识心肾贫血综合征及研究新的临床防治策略时,有必要着眼于心肾贫血综合征的内在特征并运用系统学方法原理分析其特点,为临床防治提供科学指导.     

慢性盆腔炎的中医治疗近况概述

西医对盆腔炎的治疗多流于急性期的抗炎治疗,对慢性迁延期并无切实有效的良法。中医对本病有独到见解,具有中药疗法、非药物疗法（针灸）或复合疗法三大疗法,但其治疗中存在的辩证偏向、体质忽略等不足还需解决。     

心肾贫血综合征的系统思维

心肾贫血综合征在慢性肾脏疾病患者和慢性心衰患者中大有人在,并日益受到医生重视,对其的正确认识及治疗直接影响患者的疾病预后.因此我们深入认识心肾贫血综合征及研究新的临床防治策略时,有必要着眼于心肾贫血综合征的内在特征并运用系统学方法原理分析其特点,为临床防治提供科学指导。     

The biopsychosocial approach to chronic pain: scientific advances and future directions

The prevalence and cost of chronic pain is a major physical and mental health care problem in the United States today. As a result, there has been a recent explosion of research on chronic pain, with significant advances in better understanding its etiology, assessment, and treatment. The purpose of the present article is to provide a review of the most noteworthy developments in the field. The biopsychosocial model is now widely accepted as the most heuristic approach to chronic pain. With this model in mind, a review of the basic neuroscience processes of pain (the bio part of biopsychosocial), as well as the psychosocial factors, is presented. This spans research on how psychological and social factors can interact with brain processes to influence health and illness as well as on the development of new technologies, such as brain imaging, that provide new insights into brain-pain mechanisms.     

心理性胰岛素抵抗及应对策略

糖尿病易导致严重的慢性并发症,已成为影响人们生活质量的一种常见疾病。早期应用胰岛素是使2型糖尿病患者血糖得到良好控制、减少并发症发生的有效手段。但许多患者不愿接受或延迟胰岛素治疗。本文旨在探讨胰岛素应用过程中患者及医护人员存在的心理障碍,即心理性胰岛素抵抗,并进一步阐述其应对策略。     

要重视慢性乙型肝炎的抗病毒治疗

慢性乙型肝炎是我国常见的慢性传染病之一,严重危害人民健康。围绕着乙型肝炎的防治,带来巨大的经济负担,已成为不可忽视的社会问题。在慢性乙型肝炎-肝硬化-HCC的发生发展过程中,HBV病毒载量起着重要的作用,抗病毒治疗是目前治疗慢性乙型肝炎的有效手段。因此,要重视和规范抗病毒治疗。     

经皮腔内冠状动脉成形术后再狭窄的科学认知

再狭窄 (Restenosis,RS)是随着经皮腔内冠状动脉成形术 (PTCA)等介入治疗技术用于治疗冠心病而带来的一个新的临床问题 ,严重影响了PTCA这一有效治疗方法的远期疗效。为认识了解再狭窄的发生与发展 ,达到有效防治的目的 ,过去十余年各国医学界 ,特别是心血管病学界进行了大量的研究 ,并从过程、发生机制到临床对策都取得了显著的成果。在现代科技革命条件下 ,这一认识过程有着鲜明的现代科学技术的认知特点     

Chronic social stress during adolescence in mice alters fat distribution in late life: prevention by antidepressant treatment

Obesity and visceral fat accumulation are key features of the metabolic syndrome that represents one of the main health problems in western societies due to its neurovascular and cardiovascular complications. Epidemiological studies have identified chronic stress exposure as an important risk factor for the development of obesity and metabolic syndrome, but also psychiatric diseases, especially affective disorders. However, it is still unclear if chronic stress has merely transient or potentially lasting effects on body composition. Here, we investigated the effects of chronic social stress during the adolescent period on body fat composition in mice one year after the cessation of the stressor. We found that stress exposure during the adolescent period decreases subcutaneous fat content, without change in visceral fat, and consequently increases the visceral fat/subcutaneous fat ratio in adulthood. Further, we demonstrated that treatment with a selective serotonin reuptake inhibitor (paroxetine) during stress exposure prevented later effects on body fat distribution. These results from a recently validated chronic stress paradigm in mice provide evidence that stressful experiences during adolescence can alter body fat distribution in adulthood, thereby possibly contributing to an increased risk for metabolic diseases. Antidepressant treatment disrupted this effect underlining the link between the stress hormone system, metabolic homeostasis and affective disorders.     

Chronic pain: a reformulation of the cognitive-behavioural model.

The last few decades has seen psychological theories of chronic pain dominated by behavioural concepts and particularly, by the operant model as described by Fordyce et al. (1968: Fordyce, W., Fowler, R., & DeLateur, B. (1968) An application of behavior modification technique to a problem of chronic pain. Behaviour Research and Therapy, 6, 105-107, 1976: Fordyce, W.E. (1976) Behavioral methods for chronic pain and illness. St Louis, MO: C. V Moseby). More recently, cognitive constructs have been included, giving the impression that the operant theory of chronic pain has been replaced by a cognitive-behavioural theory (CBT). Given the fact that CBTs were introduced essentially to overcome some inherent problems with operant theory, it is notable that they are still very much based on operant theory and continue to be founded upon operant principles. Further, the extent to which CBTs (at this stage) have included contemporary cognitive research has been limited. This paper argues that it is of questionable validity to continue to include problematic concepts (e.g., operant principles) into a revised theory (e.g., CBT). Instead, consistent with research from other areas (particularly the anxiety disorders), chronic pain and the problems associated with it may be better explained by a reformulated cognitive-behavioural theory which although not ignoring the observable behaviours of pain patients and their associations with social reinforcers, interprets these phenomena from a cognitive perspective. Thus, a modified CBT is proffered, focusing more directly on patients' thoughts about, and appraisals of, their pain. Evidence in support of such a theory is provided, as are suggestions for further research and the implications such a theory has for treatment.     

A Cognitive-Behavioral Model of Persistent Postural-Perceptual Dizziness

Persistent postural-perceptual dizziness (PPPD; previously termed “chronic subjective dizziness”) is a frequently observed disorder in patients who present with dizziness to audiology; ear, nose, and throat; or neurology clinics. The primary symptoms are persistent nonvertiginous dizziness, and hypersensitivity to motion and visual stimuli. These occur either in the absence of any active neuro-otologic illness or, where an episodic vestibular disorder exists, symptoms cannot be fully explained by the disorder alone. Diagnosis is necessarily multidisciplinary and proceeds by identification of primary symptoms and exclusion of other neurological or active medical disorders requiring treatment. Psychological processes are implicated in the development and maintenance of PPPD, with similarities to cognitive models of health anxiety and panic disorder, and there is evidence that cognitive-behavioral therapy is an effective treatment. A cognitive-behavioral model of PPPD is presented along with a case example. It is suggested that dizziness becomes persistent when it is processed as a threat, and that it is maintained by (a) unhelpful appraisals, (b) avoidance and safety behaviors, and (c) attentional strategies including selective attention to body sensations associated with dizziness. Once PPPD is identified techniques for its effective treatment fall within the skills mix of qualified cognitive-behavioral therapists or vestibular clinical scientists who have received additional training in cognitive and behavioral treatment.     

慢性乙肝治疗路线图和HBV DNA、HBeAg、HBsAg定量的监测意义

慢性乙型肝炎病毒感染呈世界分布并且引起不良结局,是极为严重的健康问题。慢性乙型肝炎治疗最重要的目标是长期抑制病毒以改善预后,防止出现肝硬化、肝衰竭和肝癌。目前,抗病毒药物主要有干扰素和口服核苷（酸）类似物,核苷（酸）类似物的缺点主要在于长期治疗中出现耐药。路线图概念被用于监测耐药预测疗效。HBV DNA定量水平被作为路线图较好的监测指标。由于血清转换率及清除率过低,HBeAg、HBsAg定量检测不适合用于路线图监测,但对于使用聚乙二醇干扰素的慢性乙肝患者,可作为预测治疗应答的指标。     

A Self-Management Program for Adolescents and Children with Renal Transplantation

This paper describes the development and implementation of a self-management program designed to address noncompliance in adolescents with renal transplants. Transplantation provides the best treatment alternative for End-Stage Renal Disease (ESRD), but is a procedure that subsequently demands recipients follow a life-long medication regimen. Nonadherance to medical therapy is a serious problem for adolescents; it is one of the most common causes of chronic graft rejection in this population. To improve compliance rates for this population, a self-management program was designed: (1) to provide social support; (2) to review information about medications and transplant management; and (3) to both teach and provide transplantation patients the opportunity to practice self-management skills. Details about the program, including recruitment issues and session content, are provided. Evaluations by participants indicated that the program was effective in creating a supportive environment for both patients and their parents, and in addressing health-related concerns.