A study of the effects of cranial electrical stimulation on attention and concentration

There have been several anecdotal accounts that cranial electrical stimulation (CES) enhances attention and the ability to learn new tasks in a normal population, but only one published investigation confirms that CES improves attention using the Alpha Stim CES (Madden and Kirsch, 1987). The purpose of this study was to corroborate the findings of Madden and Kirsch, using more precise measures of attention, such as a Continuous Performance Test (CPT). A pretest and posttest CPT was given to two groups using the LISS CES device. The control group consisted of twenty-one subjects who received the placebo treatment. The experimental group of thirty-one subjects received twenty minutes of CES. Four measures of the CPT show significant gains in attention: Number of Hits,p=.010 Hit RT ISI Change,p=.016, Risk Taking,p=.055; and Attentiveness,p=.054. Based on subjects who demonstrated improvement by one standard deviation on two different measures of the CPT, thirty-one percent of the experimental group improved versus four percent of the control group. The use of CES as a method of increasing attention is a promising are that requires further investigation.     

Effect of exercise-based cardiac rehabilitation on mobility and self-esteem of persons after cardiac surgery

This study adopted an experimental design with using a nonequivalent, posttest only control group to study the rehabilitation outcomes of 152 persons who received cardiac surgery. 37 subjects in a rehabilitation group participated in a 2-mo. exercise-based cardiac rehabilitation programme, and another 115 subjects who did not attend the programme formed the control group. The subjects' self-esteem was measured on the Adult Source of Self-esteem Inventory by Elvoson and Fleming, and their mobility skill was measured by a simple mobility test based on New York Heart Association Classification. Analysis of covariance (with covariance analysis of the subjects' age, years of education, occupational skill, and mobility skill) indicated that the experimental group scored higher on positive self esteem and showed significantly better improvement in mobility skill. The exercise-based cardiac rehabilitation programme positively affected physical and psychological outcomes. Also, subjects' self-esteem was significantly correlated with their mobility skills (r=.21, p<.05) among those aged under 60 years (n=96) but not among those aged 60 or above (n=53).     

Psychotherapeutic Interventions for Symptom Reduction in Veterans With PTSD: An Observational Study in a Residential Clinical Setting

Cognitive processing therapy (CPT) and eye movement desensitization and reprocessing (EMDR) therapy were compared for veterans in a posttraumatic stress disorder (PTSD) residential program (N = 51) who received individual EMDR and group CPT, individual CPT and group CPT, or trauma group exposure (TGE) therapy. Analyses revealed an overall significant difference on posttest measures of the PTSD Checklist for individual EMDR/group CPT and individual CPT/group CPT when compared to TGE, with no significant difference found between EMDR and CPT. Depression scores were significantly decreased between pre- and posttest for patients who received individual EMDR/group CPT. Results support EMDR and CPT as clinically effective and complementary treatments in residential PTSD treatment programs.     

A rehabilitative program for central executive deficits after traumatic brain injury

Deficits affecting Central Executive System (CES) of working memory (WM) are the main neuropsychological outcome after traumatic brain injury (TBI) and can also explain deficits in other domains, like divided attention, executive functions and long-term memory. For this reason we developed a rehabilitative program based on CES functions and we expected to find an improvement in WM as well as in those cognitive functions controlled by the CES.The experimental group was composed by 9 TBIs, selected for WM deficits, whereas the control group was composed by 6 TBIs, without WM deficits, but with speed processing deficits. All patients performed a cognitive training, based on PASAT (Gronwall & Wrightson, 1981)and two new versions of this task.The results showed in the experimental group an improvement in WM and in the cognitive functions controlled by the CES, whereas control patients did not show any improvement after the cognitive training.     

Comparative effects of microcurrent stimulation on EEG spectrum and correlation dimension

Two mathematical derivatives of electroencephalogram (EEG), Fast Fourier Transform (FFT), and correlation dimension from chaos analysis were used to assess the objective effects of earlobe versus mid-trapezius microcurrent stimulation on brain EEG. These measures were considered to be clinically relevant since low points in the FFT have been associated with attention deficit disorder, and declining correlation dimension has been associated with onset of epilepsy. Thirty Subjects (30) were assigned randomly to one of three groups: earlobe, trapezius, and a double blind placebo control Earlobe stimulation (CES) was hypothesized to alter BEG since research suggests CES enters the brain directly, through a perineural or vascular path via the auditory meatus. Results showed that trapezius microcurrent therapy proved more effective in producing significant declines in FFT spectral smoothing, with an average standard deviation (SD) in the FFT of 1.1, as compared to the CES group showing an SD of 2.9. Correlation dimension in both trapezius and CES stimulation groups increased significantly (p<.001) as compared to placebo, with the correlation dimension measures for earlobe, trapezius, and placebo being 5.7, 5.6, and 3.7, respectively. The author discusses the significance of using body points for promoting clinically beneficial effects in brain electrophysiology as evidenced by improved FFT and correlation dimension.     

A meta-analytic review of cognitive processing therapy for adults with posttraumatic stress disorder

Numerous studies have demonstrated the efficacy of cognitive processing therapy (CPT) for treating posttraumatic stress disorder (PTSD). Two prior meta-analyses of studies are available but used approaches that limit conclusions that can be drawn regarding the impact of CPT on PTSD outcomes. The current meta-analysis reviewed outcomes of trials that tested the efficacy of CPT for PTSD in adults and evaluated potential moderators of outcomes. All published trials comparing CPT against an inactive control condition (i.e. psychological placebo or wait-list) or other active treatment for PTSD in adults were included, resulting in 11 studies with a total of 1130 participants. CPT outperformed inactive control conditions on PTSD outcome measures at posttreatment (mean Hedges’ g = 1.24) and follow-up (mean Hedges’ g = 0.90). The average CPT-treated participant fared better than 89% of those in inactive control conditions at posttreatment and 82% at follow-up. Results also showed that CPT outperformed inactive control conditions on non-PTSD outcome measures at posttreatment and follow-up and that CPT outperformed other active treatments at posttreatment but not at follow-up. Effect sizes of CPT on PTSD symptoms were not significantly moderated by participant age, number of treatment sessions, total sample size, length of follow-up, or group versus individual treatment; but, older studies had larger effect sizes and percent female sex moderated the effect of CPT on non-PTSD outcomes. These meta-analytic findings indicate that CPT is an effective PTSD treatment with lasting benefits across a range of outcomes.     

Individualized behavior therapy for alcoholics: a third year independent double-blind follow-up.

An independently conducted double-blind study providing third year follow-up data for 53 of 70 male alcoholics who served as subjects in an experiment evaluating “Individualized Behavior Therapy (IBT)” techniques is reported. In the original study, subjects were initially assigned to either a controlled drinking or non-drinking (abstinence) treatment goal, and were then randomly assigned to either an experimental group receiving IBT or a control group receiving conventional state hospital treatment oriented towards abstinence. Previously reported results showed that IBT subjects functioned significantly better than control subjects throughout the first year of follow-up. Second year follow-up results found that IBT subjects treated with a controlled drinking goal functioned significantly better than their respective control subjects on a variety of measures, including drinking behavior. Differences between IBT subjects treated with a non-drinking goal and their control subjects did not retain statistical significance during the second year of follow-up. The independently determined follow-up data showed that during the third post-treatment year, subjects in the experimental groups generally functioned better than their respective control subjects. Comparison of the controlled drinking experimental group with its control group showed the significantly better functioning of subjects in the experimental condition on a number of drinking and other life functioning measures. Comparison of the non-drinking groups indicated only one possible difference on the drinking related measures involving a trend for subjects in the experimental condition to abstain more than those in the non-drinker control group. On other life functioning measures, however, subjects in the non-drinking experimental condition showed consistent improvement over their respective control subjects. Both of the controlled drinking groups reported more controlled drinking days than the non-drinking groups throughout the third year follow-up period.     

The effects of the Let's Get Rational board game on rational thinking,depression, and self-acceptance in adolescents

The present study investigated the effects of the Let's Get Rational board game on rational thinking, depression, and self-acceptance in high school students. A sample of 80 subjects (40 male, 40 female) was selected for participation in this study. Four experimental groups of 10 students played the board game Let's Get Rational for one 52 minute class period once a week for seven weeks. Three dependent measures were used. These included a measure of rational thinking (Child and Adolescent Scale of Irrationality), a measure of depression (Beck Depression Inventory), and a measure of self-acceptance (Adjective Generation Technique). Cell means were calculated for the following independent variables: 1) treatment vs. no treatment, 2) gender—male vs. female, and 3) grade level—9th, 10th, 11th, and 12th. Results indicated that the subjects in the experimental group agreed with fewer irrational beliefs than subjects who received no treatment. Ninth grade experimental subjects reported less irrational thinking than did 9th-grade control group subjects. Finally, 10th-grade experimental subjects were significantly less depressed than 10th-grade control subjects.     

Does the Conners' Continuous Performance Test Aid in ADHD Diagnosis?

The performance of clinic-referred children aged 6–11 (N = 100) was examined using the Conners' Continuous Performance Test (CPT) and measures of auditory attention (Auditory Continuous Performance Test; ACPT), phonological awareness, visual processing speed, and visual-motor competence. The Conners' CPT overall index was unrelated to measures of visual processing speed or visual-motor competence. Although the Conners' CPT converged with the ACPT, the latter demonstrated age and order effects. Significant variance in Conners' CPT parameters was predicted by phonological awareness measures, suggesting that Reading Disordered (RD) children could be false positives on the Conners' CPT. The Conners' CPT overall index, phonological awareness, and visual-motor measures were submitted to a 2×2 MANCOVA (ADHD vs. RD, covarying for age and socieoeconomic status): a main effect for RD status was found. Children with ADHD did not have higher Conners' CPT scores than did clinical controls; however, children with Reading Disorders did. Phonological measures distinguished RD children from ADHD children and other clinical controls. ADHD children who failed the Conners' CPT were rated by teachers as more hyperactive. Despite the strengths of the Conners' CPT, its utility for differential diagnosis of ADHD is questioned.     

Bladder training and enuresis: A controlled trial

This study was designed to test the effectiveness of a short bladder training procedure to increase bladder capacity and to improve enuresis. Eighteen enuretic children, aged 5–13 years, were randomly assigned to either an experimental or control group. Pre- and post-treatment measures of bladder capacity and frequency of bedwetting were obtained from subjects in both groups. The experimental group received 35 days of bladder training administered at first by the experimenter and then by the parents. The training consisted of required drinking, practice in holding and rewards for retaining progressively larger volumes of fluid before voiding. The control group received no training during the duration of the experiment. The results showed that the mean bladder capacity of the experimental subjects increased significantly with bladder training compared to controls. However, the frequency of bedwetting of the experimental subjects did not decrease significantly with training. Consequently, the efficacy of a bladder training procedure in the treatment of enuresis is questioned     

Improving the quality of parental interaction with very low birth weight children: A longitudinal study using a Mediated Learning Experience model

Cognitive performance of 3-year-old, very low birth weight children (N = 42) was found to be more significantly related to the quality of parent-child interaction than to early measures of cognitive performance or measures of developmental risk such as birth weight and APGAR. The subjects were randomly divided into an intervention and a control group. The intervention group was visited at home, infrequently, by a mediator who identified basic criteria of quality of parent-child interaction and provided the parents with feedback on the quality of interaction with their own children. The intervention procedure continued for 7 months. The extent of a family's participation in the intervention varied depending upon the initial quality of parent-child interaction and the amount of time it took a family to reach criteria. Quality of parent-child interaction and children's cognitive performance were pretested and reassessed 3 years after the intervention. The sample was reduced to 29 due to attrition over time. Parental behavior following the intervention had changed significantly with respect to all criteria. Parents who had received intervention, as compared to the control group parents, provided their children with more behaviors related to focusing attention, exciting and rewarding, expanding children's understanding of the world around them, preplanning and regulating behavior. Three years after the relatively unintensive intervention, parents continued to show significant gains in quality of mediation. Differences were found between parents of Small for Gestational Age (SGA) and Appropriate for Gestational Age (AGA) children in favor of the SGA group. In children's cognitive performance, scores of the intervention group on the Peabody Picture Vocabulary Test (PPVT) were significantly higher than those of the control group. On other cognitive measures, a consistent trend in favor of the intervention group was noted. More children in the control as compared to the experimental group were rated by their parents as having difficulties with language, fine motor, and sociability skills 3 years after the intervention.     

Group Counseling with College Underachievers

Some of the controversy concerning the efficacy of psychotherapy or counseling has been resolved by recent evidence that studies reporting no effects had indiscriminately lumped together the high and low therapeutic conditions that are associated with successful and unsuccessful outcomes. The present study extends these findings to a group of essentially neurotic underachieving college freshmen. The 24 experimental students who received group counseling showed greater improvement in grade-point average than 24 matched, non-counseled control subjects. Further, those counseled subjects who received the highest therapeutic conditions tended to show the greatest improvement.     

Self-directed attention and taking the other's perspective

A series of experiments was conducted to assess the influence of self-directed attention on the ability to take another's perspective. In Experiment 1 subjects who listened to a recording of their own voice were better able to orient themselves to the perspective of another than were subjects in a control group. However, the presence of concern about a potentially negative aspect of the self eliminated the positive relationship between self-directed attention and other orientation. Experiment 2, with the same experimental conditions as in Experiment 1, investigated the relationship between self-focused attention and selfattribution for a group product. The results indicated that self-awareness lessened the tendency of subjects within a group to “overattribute” responsibility for the group product to oneself. Again, self-focused attention did not improve self-other differentiation when subjects were concerned about a potentially negative aspect of the self. A final experiment (3) was a conceptual replication of Experiment 1, using a different perspective-taking measure and a different method of inducing self-focus.     

The use of structured learning therapy and transfer programming with disruptive adolescents in a school setting

In behavior change literature, little attention has been paid to the systematic study of variables affecting transfer of training. The present study employed a skill-training method known as Structured Learning Therapy (SLT) for the dual purpose of testing the effectiveness of this method and to identify variables that will promote transfer of training. Forty-three disruptive male adolescents were assigned to three experimental and two control conditions. One experimental group received SLT plus an additional transfer-enhancing procedure referred to as Transfer Programming (TP) which consisted of in vivo practice of treatment gains and peer reinforcement. Another group received only SLT, and a third group received only TP. One control group received only brief instructions pertaining to the nature of the skill, while the second group served as an attention control. Consistent with predictions, the results were that the two groups receiving the SLT performed significantly better than the three groups not receiving SLT on all dependent measures at posttest. These differences generally maintained at follow-up. Contrary to expectations, the implementation of TP did not prove to promote transfer of training beyond that found with SLT alone.     

Visual Information Processing Speed in Hypnotized and Nonhypnotized Subjects

Using a backward-masking paradigm with a bias-free and ceiling-free psychophysical task, we tested hypnotized and control subjects for speed of visual information processing. Approximately half of each group received visual imagery suggestions in an attempt to influence attention. Imagery produced no significant differential effect. Although an absence of a hypnotizability-performance relationship was in keeping with findings of a previous study, those subjects in the present study who performed under hypnosis were, as a group, significantly superior to the other subjects in speed of information processing.     

AULA virtual reality test as an attention measure: Convergent validity with Conners’ Continuous Performance Test

The majority of neuropsychological tests used to evaluate attention processes in children lack ecological validity. The AULA Nesplora (AULA) is a continuous performance test, developed in a virtual setting, very similar to a school classroom. The aim of the present study is to analyze the convergent validity between the AULA and the Continuous Performance Test (CPT) of Conners. The AULA and CPT were administered correlatively to 57 children, aged 6–16 years (26.3% female) with average cognitive ability (IQ mean = 100.56, SD = 10.38) who had a diagnosis of attention deficit/hyperactivity disorder (ADHD) according to DSM-IV-TR criteria. Spearman correlations analyses were conducted among the different variables. Significant correlations were observed between both tests in all the analyzed variables (omissions, commissions, reaction time, and variability of reaction time), including for those measures of the AULA based on different sensorial modalities, presentation of distractors, and task paradigms. Hence, convergent validity between both tests was confirmed. Moreover, the AULA showed differences by gender and correlation to Perceptual Reasoning and Working Memory indexes of the WISC-IV, supporting the relevance of IQ measures in the understanding of cognitive performance in ADHD. In addition, the AULA (but not Conners’ CPT) was able to differentiate between ADHD children with and without pharmacological treatment for a wide range of measures related to inattention, impulsivity, processing speed, motor activity, and quality of attention focus. Additional measures and advantages of the AULA versus Conners’ CPT are discussed.     

An electrophysiological study of school-aged children with a history of failure to thrive during infancy

Sixty-five subjects, ages 8 to 12, participated in a visual electrophysiological study. Twenty-two of the subjects had received a diagnosis of nonorganic failure-to-thrive (FTT) before the age of three. The remaining 43 subjects had no history of FTT and served as Controls. IQs were obtained with the abbreviated WISC-III, and the Controls were split into two groups, LO IQ and HI IQ, to provide a LO IQ Control group with an average IQ equivalent to the FTT group. Event-related brain potentials (ERPs) were recorded from five scalp locations during a cued continuous performance task (CPT). Subjects had to press a button every time they saw the letter “X” following the letter “A” (50 targets out of 400 stimuli). During the CPT, the FTT subjects made marginally more errors of omission to targets than the LO IQ Control group and significantly more errors of omission than the HI IQ Control subjects. The groups did not differ significantly on errors of commission (false alarms) or reaction times to targets. ERP averages revealed a group difference in amplitude in a late slow wave for the 50 non-X stimuli (false targets) that followed the letter A. This difference was greatest over frontal sites, where the FTT group had a more negative going slow wave than each control group. Late frontal negativity to No Go stimuli has been linked with post-decisional processing, notably in young children. Thus, the FTT subjects may have less efficient inhibitory processes, reflected by additional late frontal activation. *** DIRECT SUPPORT *** A31BB040 00006     

Visual information processing speed in hypnotized and nonhypnotized subjects

Using a backward-masking paradigm with a bias-free and ceiling-free psychophysical task, we tested hypnotized and control subjects for speed of visual information processing. Approximately half of each group received visual imagery suggestions in an attempt to influence attention. Imagery produced no significant differential effect. Although an absence of a hypnotizability-performance relationship was in keeping with findings of a previous study, those subjects in the present study who performed under hypnosis were, as a group, significantly superior to the other subjects in speed of information processing.     

Effects of rational emotive education on the rationality, neuroticism and defense mechanisms of adolescents

The purpose of this study was to assess the efficacy of rational emotive education (REE) as a mental health prevention program for adolescents. The subjects included 109 eleventh- and twelfth-grade students enrolled in four introductory psychology courses, and who were divided into experimental and control classes. Experimental subjects received 12 biweekly sessions of REE. Subjects were pre- and posttested on three measures of psychosocial adaptation: the Rational Behavior Inventory (RBI), the Defense Mechanism Inventory (DMI), and the Eysenck Personality Inventory (EPI). The effects of REE upon behavior were also examined by comparing academic effort grades, number of detentions, and grade point averages. Overall results showed significant positive changes in use of more adaptive defense mechanisms and in academic effort grades in the predicted direction. No significant changes occurred on the other measures. However, as a distinctive group, 17-year-olds demonstrated a significant reduction in neuroticism scores and a significant increase in academic effort grades.     

CGRP和VIP与先天性胫骨假关节的相关性研究

为了明确降钙素基因相关肽（CGRP）、血管活性肠肽（VIP）在先天性胫骨假关节（CPT）病变组织中的表达,取10例CPT病变骨膜作为实验组,以10例正常骨膜作为对照组,采用免疫组化方法检测两组标本中CGRP、VIP的表达。结果显示,CGRP、VIP在CPT的骨膜中较对照组表达减弱。因此,CGRP和VIP在CPT中的异常表达可能是导致CPT的因素之一。