癌症病人的生活质量及心理干预研究

本研究在前期研究的基础上进一步探讨癌症病人的生活质量状况和心理干预的效果。运用病例对照实验设计 ,选用生活质量问卷 (QLQ C3 0 )作为主要测查工具 ,采用两因素混合实验方差分析统计方法 ,对 1 2 0名住院化疗病人进行了比较分析。结果显示 :躯体功能 (PF)、角色功能 (RF)、情绪功能(EF)、认知功能 (CF)和整体生活质量 (QL)得分在治疗前后和实验与对照组之间的交互作用均显著和非常显著 ;症状量表和单项症状中交互作用显著和非常显著的有 :疲乏 (FA)、呼吸困难 (DY)、失眠 (SL)、食欲丧失 (AP)。因此 ,化疗对病人的生活质量有明显的影响 ,经心理干预后癌症病人的各种功能状况和症状得到不同程度的改善。     

肺癌患者心理痛苦的研究进展

肺癌是最常见的恶性肿瘤之一,因其病情较重,治疗效果不佳,预后不良,患者常存在严重的心理痛苦。心理痛苦是由多重因素引起的一种不愉快的情绪体验,影响着患者的治疗依从性及身心症状,降低肺癌患者的生命质量。本文着重从相关因素、干预措施等方面综述肺癌患者心理痛苦的研究现状及进展。全面检索分析文献后发现:吸烟、病程、治疗方式、症状负担等均可不同程度引起肺癌患者心理痛苦;有效的干预方式主要有心理社会干预、药物干预及补充替代疗法。临床工作者应加强对肺癌患者心理痛苦的关注。     

抑郁症计算机化治疗的效果及其影响因素：基于RCT的元分析与元回归分析

运用元分析和元回归分析的方法考察抑郁症计算机化治疗的效果及其影响因素。来源于50篇文献,42项RCT研究的67个样本满足了元分析标准（N=7920）。结果发现：（1）整体效果量为0.53,三个月追踪效果量为0.14;6个月追踪效果量为0.16;（2）在年龄段、抑郁严重程度、支持方式和测量量表四个亚组分析中,其效果量存在显著差异。干预方式、干预取向和分析方法对效果量的影响不显著;（3）出版年份显著影响治疗效果量,脱落率和干预单元数对整体效果量的影响不显著。结果表明：抑郁症的计算机化治疗具有中等的效果量;年龄段、抑郁严重程度、支持方式、测量量表和出版年份对其整体效果量有调节作用。将来抑郁症计算机化治疗的研究应重视上述调节变量对治疗效果的影响。     

心理干预在放疗患者中的应用

探讨通过实施恰当的心理行为治疗,尤其是教育性干预措施,达到改善放疗患者情绪、提高其生活质量以及降低治疗负反应的效果.采用病例对照的临床研究方法,选用生活质量和心境问卷对160名正在进行放射治疗的住院癌症病人进行了心理干预的比较研究.结果表明,干预组患者的总体情绪和总体生活质量状况,比对照组患者有明显的改善,但愤怒、认知功能以及恶心呕吐症状在两组间的差异不显著;干预组组内比较中,角色功能没有显著性差别.其原因有待于进一步研究.     

归因方式对心理健康的影响及干预研究之概观

该文就归因方式对心理健康影响的特点、规律及其心理机制以及通过归因干预改善和提高个体与群体健康水平的研究进行了简要的叙述,并对已有研究存在的问题进行了初步的讨论。作者认为,归因干预可能是改善和提高个体与群体的健康水平的一条重要途径;未来的研究应着眼于揭示个体对不同性质、不同类型的生活事件在特定归因和维度归因上对心理健康影响的特点、规律及其心理机制,并就归因干预的理论和实践等问题进行了深入的探讨。     

集体心理干预对癌症患者应对方式影响的研究

为了探索集体心理干预对癌症患者应对方式的影响,本研究在90名癌症患者中随机选取46人进行干预研究。为考察干预效果,在干预后分别以医学应对方式问卷各维度因子的前测得分为协变量,以医学应对方式问卷各维度因子的后测得分为因变量,进行2(分组:实验组、对照组)×2(性别:男、女)×3(年龄:低龄组、中龄组、高龄组)的三因素协方差分析。结果表明,经过集体心理干预的实验组在应对方式各分量表上的得分要显著高于对照组,集体心理干预在性别和年龄上不存在显著差异。研究结果表明集体心理干预能够有效地改善癌症患者的应对方式。     

乳腺癌保乳治疗的进展与临床选择

保乳治疗既能满足乳腺癌的治疗要求,又适于追求更高的生活质量,但应用时必须严格掌握适应证,还要充分考虑到病人及其家庭的经济和心理承受能力,医院的综合治疗条件等因素,充分做到科学性与人性化的高度结合,才能获得最佳临床效果.     

乳腺癌保乳治疗的进展与临床选择

保乳治疗既能满足乳腺癌的治疗要求,又适于追求更高的生活质量,但应用时必须严格掌握适应证,还要充分考虑到病人及其家庭的经济和心理承受能力,医院的综合治疗条件等因素,充分做到科学性与人性化的高度结合,才能获得最佳临床效果。     

解析城市中学生的消费心理与消费行为

城市中学生所接受的教育、所处的校园环境以及该年龄特殊的心理特征等因素使得这一阶段的个体有着特殊的消费心理和消费行为。对他们的消费心理和消费行为进行研究,提出相应的建议及对策,是有现实意义的。本文对当代城市中学生的消费水平、消费方式、消费心理的特点及其影响因素作了分析讨论并提出干预的对策。     

生理心理社会综合诊疗对原发性高血压的疗效观察

观察生理心理社会综合诊疗对原发性高血压(EH)患者的疗效。EH患者162例,采用随机数字表法分为干预组(生理心理社会综合诊疗)和对照组(常规诊疗),比较两组在血压控制率、服药依从性、再住院次数、心理状况、生活方式、社会境遇、就诊满意度方面的效果。干预组的血压控制率较对照组高(P0.05);干预组较对照组的服药依从性高、再住院次数少(P0.05),干预组的心理状况、生活方式、社会境遇、就诊满意度较对照组改善(P0.05)。生理心理社会综合诊疗对EH的控制具有一定的临床意义。     

心理干预在化疗患者中的应用

本研究针对化疗患者常见的恶心呕吐、烦躁不安等副作用．运用心理行为技术．采用病例对照研究方法,对129名化疗患者进行了比较研究。结果为：各项情绪指标和总的情绪状况以及恶心呕吐反应。干预组患者比对照组改善明显;生活质量各指标在组问和组内比较中,有不同程度的改善,角色、社会、认知功能和疼痛症状在两组比较中改善不明显。由此认为,对化疗患者实施恰当的心理行为技术．干预效果是明显的     

心理行为干预对乳腺癌患者情绪反应及免疫功能的影响

按随机和匹配原则,将40名乳腺癌放疗患者分入干预组和对照组。对干预组患者进行为期4周的心理行为干预,对照组仅接受相应的医药治疗。以肿瘤病人情绪适应问卷(MAC)和免疫测试法研究患者干预前后的情绪反应和免疫功能,探讨心理行为干预对乳腺癌患者情绪反应和免疫功能的影响。结果发现,心理行为干预有利于提高患者NK细胞活性(NKCA);并有助于维持放疗期间患者的白细胞水平。     

榄香烯联合替莫唑胺与单药替莫唑胺在 NSCLC 脑转移放疗后维持治疗中的比较研究

探讨榄香烯注射液联合替莫唑胺在非小细胞肺癌（NSCLC）脑转移患者放疗后维持治疗的疗效,将46例NSCLC脑转移放疗后患者,随机分为联合治疗组和对照组,分别采用榄香烯联合替莫唑胺和单药替莫唑胺维持化疗,观察两组疗效、免疫指标、不良反应及生存分析。结果显示两组无进展生存期（PFS）、总生存期（OS）差异无统计学意义（P＞0．05）。总缓解率及卡氏功能状态评分（KPS）两组比较差异有统计学意义（P＜0．05）。联合治疗组免疫功能提高,化疗不良反应减轻。榄香烯联合替莫唑胺维持治疗可以提高NSCLC脑转移患者放疗后的总缓解率,改善生活质量,减轻化疗的不良反应,应用安全。     

Web-based remote psychological intervention improves cancer treatment

Web-based-remote (WBR) intervention is a new approach that incorporates smart control technology and modern medicine to monitor patient compliance. It is based on computer control and communication technology. This study is to explore the benefits of WBR psychological intervention for cancer treatment. 128 patients diagnosed with cancer by Pathology Department of our hospital between 1 February 2013 and 1 August 2013 were included. Patients were randomly assigned to intervention and control group (n = 64). The Questionnaire-Core 30 (QLQ-C30) was used for the survey. Intervention group received WBR psychological intervention in addition to regular clinical follow-up care. Control group only received regular clinical follow-up care. The QLQ-C30 score was significantly better in the intervention group than the control group when the intervention and control groups were followed for three months. In conclusion, WBR psychological intervention substantially improves the quality of life in patients during cancer treatment.     

Evaluation of a psychosocial intervention on social support, perceived control, coping strategies, emotional distress, and quality of life of breast cancer patients

The purpose of this research was to demonstrate that a specific psychosocial intervention changes reactions to cancer and quality of life. This study was carried out on 66 patients with a first breast cancer. Patients were randomly divided into two groups: a specific intervention group (G1, 8 sessions) or a support group (G2, 8 sessions). A control group (G3) was composed of patients who refused to participate in psychological intervention. Social support, perceived control, repression of emotions, coping strategies, emotional distress, and quality of life were assessed one week before (T1) and at the end (T2) of the psychological intervention. Results showed that G1 did not have significantly modified quality of life or psychological scores. Patients of G2 had poorer emotional quality of life, use of internal causal attributions, and minimized their illness at T1 as compared to patients of G3. At Time 2 these differences were not observed.     

住院放化疗肺癌患者生活质量影响因素分析

生活质量研究是近年来肿瘤治疗研究的热点之一。应用生存质量核心问卷（QLQ—C30）及卡氏功能量表,于治疗前、中、后进行问卷式调查,探讨60例经病理证实接受放、化疗的肺癌患者生活质量的影响因素,预测患者预后和远期生存状态,为住院放化疗肺癌的治疗方法提供一个较好的参考标准,对放化疗肺癌的治疗水平和改善生活质量起到了一定的推动作用。     

Comparing the effectiveness of behavioral treatment for chemotherapy-induced nausea and vomiting when administered by oncologists, oncology nurses, and clinical psychologists.

Adequate control of side effects during medical treatment of cancer increases patient compliance and quality of life. Antiemetic drugs are not an effective treatment for the one in three cancer patients on chemotherapy who experience anticipatory nausea and vomiting (ANV); the behavioral treatment of systematic desensitization has been found effective for ANV when delivered by clinical psychologists. This study examined the effectiveness of systematic desensitization when delivered by medical personnel versus clinical psychologists. Seventy-two consecutive cancer patients with ANV were randomly assigned to no-treatment control or to systematic desensitization from 5 behaviorally trained clinical psychologists, 6 clinical oncologists, or 10 oncology nurses. The treatment was found effective in reducing anticipatory nausea, anticipatory vomiting, posttreatment nausea, and posttreatment vomiting compared to control patients, with no significant differences in effectiveness found between clinical psychologists and oncology staff. Although medical personnel should not engage patients in psychotherapy or other interventions that cannot be completed successfully, they can treat patients effectively with systematic desensitization and should be encouraged to learn and use this and other behavioral intervention techniques to benefit total patient care.     

Optimizing preoperative expectations in cardiac surgery patients is moderated by level of disability: the successful development of a brief psychological intervention

Patients’ expectations have shown to be a major psychological predictor of health outcome in cardiac surgery patients. However, it is unclear whether patients’ expectations can be optimized prior to surgery. This study evaluates the development of a brief psychological intervention focusing on the optimization of expectations and its effect on change in patients’ expectations prior to cardiac surgery. Ninety patients scheduled for coronary artery bypass graft were randomly assigned to (1) standard medical care, (2) additional expectation manipulation intervention (EMI), and (3) additional attention control group. Therapists’ fidelity to intervention manuals and patients satisfaction with the intervention were assessed for both active intervention conditions. Patients’ expectations about post-surgical disability, treatment control, personal control, and disease duration were assessed before and after the psychological intervention. Demographical, medical, and psychosocial characteristics and disability were assessed at baseline. Treatment fidelity and patient satisfaction was very high in both intervention conditions. Only patients receiving EMI developed higher personal control expectations and longer (more realistic) expectations of disease duration. The effect of intervention group on patients’ disability expectations and patients’ personal control expectations was moderated by patient’s level of disability. EMI patients with low to moderate disability developed positive expectations whereas patients with high disability did not. This study shows the successful development of a short psychological intervention that was able to modify patients’ expectations, especially in those with low to moderate disability. Given the robust association of expectations and surgery outcome, such an intervention might offer the opportunity to enhance patients’ health following cardiac surgery.     

Effectiveness of therapy group in women with localized breast cancer

Background/ObjectiveBreast cancer causes high levels of anxiety and depression, deteriorating quality of life of patients. Several studies have found that group therapy reduces depression and anxiety also improves the quality of life. The aim of this study is to analyze group therapy effectiveness in emotional state and quality of life in women with breast cancer after finalized medical treatments.MethodParticipants in this study were 100 adult women diagnosed of breast cancer non-mestastasic and were divided into two types of intervention groups (Self-esteem-Social Skills and Cognitive-Behavioral Therapy). Evaluation instruments were questionnaire Functional Assessment of Breast-cancer Therapy (FACT-B) and Hospital Anxiety and Depression Scale (HADS).ResultsA statistically significant effect of group therapy in reducing anxiety and depression were observed. Quality of life and emotional well-being significantly improved. These effects remain three months after intervention.ConclusionsThe results show that the psychological intervention group is efficient to improve emotional state and quality of life of women with breast cancer.