Interactive effects of subjective memory complaints and hypertension on learning and memory performance in the elderly

This study evaluated whether the relation between subjective memory complaints and cognitive performance is influenced by the presence of hypertension in the elderly. One hundred and five healthy older adults, 70–89 years of age, with and without hypertension treatment or diagnosis, completed a scale of subjective memory complaints. Participants were divided into those with mild memory concerns and those with minimal or no complaints. All participants completed a battery of neuropsychological tests including measures of verbal and nonverbal memory. After controlling for differences in age, gender, education, and overall intellectual ability, there were significant main effects for memory concerns and significant interactions for memory complaints and hypertension on several measures of memory performance. There were no main effects for hypertension on memory performance. Simple effects analyses of the interactions showed that the hypertensive complainers demonstrated poorer performance on measures of long-term memory and greater reliance on short-term recall than the hypertensive non-complainers. There were no differences in memory performance for the non-hypertensive groups. Among healthy elderly community-dwelling adults, those with mild subjective memory complaints in the context of hypertension demonstrated greater objective cognitive difficulties than those without hypertension as well as a greater reliance on a less efficient learning strategy. These findings suggest that memory concerns in the presence of hypertension may be important when evaluating treatment efficacy in these individuals and for identifying differences in cognitive aging.     

Protective role of educational level on episodic memory aging: An event-related potential study

The aim of the present experiment was to investigate whether educational level could modulate the effect of aging on episodic memory and on the electrophysiological correlates of retrieval success. Participants were divided into four groups based on age (young vs. older) and educational level (high vs. low), with 14 participants in each group. Event-related potentials (ERP) were recorded while participants performed a word-stem cued-recall task. Age-related memory deficits were greater for the less educated individuals. Age differences in the ERP old/new effects were also modulated by the level of education. This study demonstrated that the effects of age on episodic memory and ERP correlates of retrieval success are smaller in participants with high educational levels than those with lower levels. These findings provide support for the reserve hypothesis and highlight the need to consider individual differences when studying cognitive and cerebral changes in aging.     

老年人记忆补偿的长期稳定性和变异性：来自维多利亚纵向研究的证据

两种记忆状况组来自于参与加拿大维多利亚纵向研究(VLS)的老年人原样本。一种是未受损伤的控制组(NIC), 另一种是轻度记忆损伤组(MMD)。在基线水平和纵向水平上(即5次追踪或12年)比较了他们在日常生活中对记忆补偿技术的使用。我们使用多水平模型(以年龄和教育水平为协变量)来检验基线水平的差异和长期的变化模式。基线的结果表明MMD组被试报告了近期在日常生活中使用记忆补偿策略方面有更大的增长。纵向的结果表明记忆补偿的使用在12年中具有明显的稳定性, 但是与努力相关的补偿机制存在显著组间差异。教育水平这一协变量(可认为是潜在的认知储备指标)和三种记忆补偿策略随时间的不同变化相关。     

Relationship between frequency of involuntary autobiographical memories and cognitive failure

Involuntary autobiographical memories are memories of personal experiences that pop into mind without a conscious attempt at their retrieval. This study investigated individual differences in the number of involuntary autobiographical memories, and explored the relationship between the frequency of occurrence in involuntary autobiographical memory and cognitive failures in everyday memory, as indexed by metamemory questionnaires. A total of 24 undergraduate students reported involuntary autobiographical memories in controlled field interviews, and completed the Everyday Memory Questionnaire and the Cognitive Failures Questionnaire. The results showed that, despite controlled conditions, considerable individual differences were observed in the number of involuntary autobiographical memories reported while walking along a prescribed route on the campus, and that reported memories were predominantly serving self function. In addition, the number of involuntary autobiographical memories was positively related to cognitive failures in everyday memory: participants who acknowledged more problems in everyday memory had a higher frequency of involuntary memories. The implications of these results are discussed in terms of the complementary function of involuntary autobiographical memory in everyday life.     

Episodic and semantic memory in bilingual and monolingual children

Although bilinguality has been reported to confer advantages upon children with respect to various cognitive abilities, much less is known about the relation between memory and bilinguality. In this study, 60 (30 girls and 30 boys) bilingual and 60 (30 girls and 30 boys) monolingual children in three age groups (mean ages 8.5, 10.5 and 12.5 years) were compared on episodic memory and semantic memory tasks. Episodic memory was assessed using subject-performed tasks (with real or imaginary objects) and verbal tasks, with retrieval by both free recall and cued recall. Semantic memory was assessed by word fluency tests. Positive effects of bilingualism were found on both episodic memory and semantic memory at all age levels. These findings suggest that bilingual children integrate and/or organize the information of two languages, and so bilingualism creates advantages in terms of cognitive abilities (including memory). Some sex differences were also found in episodic memory but not in semantic memory. This episodic memory difference was found with younger children.     

Cognitive functioning in healthy older adults aged 64-81: a cohort study into the effects of age, sex, and education

The objective of this study was to determine a possible differential effect of age, education, and sex on cognitive speed, verbal memory, executive functioning, and verbal fluency in healthy older adults. A group of 578 healthy participants in the age range of 64-81 was recruited from a large population study of healthy adults (Maastricht Aging Study). Even in healthy individuals in this restricted age range, there is a clear, age-related decrease in performance on executive functioning, verbal fluency, verbal memory, and cognitive speed tasks. The capacity to inhibit information is affected most. Education had a substantial effect on cognitive functioning: participants with a middle or high level of education performed better on cognitive tests than did participants with a low level of education. Women performed better than men on verbal memory tasks. Therefore, education and sex must be taken into account when examining an older individual's cognitive performance.     

The effects of marital status on episodic and semantic memory in healthy middle-aged and old individuals

The present study examined the influences of marital status on different episodic and semantic memory tasks. A total of 1882 adult men and women participated in a longitudinal project (Betula) on memory, health and aging. The participants were grouped into two age cohorts, 35-60 and 65-85, and studied over a period of 5 years. Episodic memory tasks concerned recognition and recall, whereas semantic memory tasks concerned knowledge and fluency. The results showed, after controlling for education, some diseases, chronological age and leisure activity as covariates, that there were significant differences between married and single individuals in episodic memory, but not in semantic memory. Married people showed significantly better memory performances than singles in both subsystems of episodic memory, that is, recall and recognition. Also, the rate of decline in episodic memory was significantly larger for singles and widowed than other groups over the 5-year time period in both age groups. The findings demonstrate that the positive relation found between marriage and health can be extended to the relation between marriage and cognitive performance. This effect might be explained by the role played by cognitive stimulation in memory and cognition.     

The relation between verbal and visuospatial memory and autobiographical memory

The basic-systems approach (Rubin, 2005, 2006) states that autobiographical memory is supported by other cognitive systems and argues that autobiographical memories are constructed from interactions between cognitive systems, such as language, vision and emotion. Although deficiencies in one or more of the basic systems influence the properties of autobiographical memories, little is known about how these cognitive abilities and autobiographical memory are related. To assert whether participants with stronger cognitive abilities also perform better on autobiographical memory tests, participants who completed verbal and visuospatial memory tests also recorded one personal event, which they recalled after a certain interval. Participants who performed well on the verbal memory tests also had better retention for the personal event, providing support for the basic-systems approach to autobiographical memory and preliminary support for the view that people have more memories from adolescence and early adulthood because the memory system works optimally in these lifetime periods.     

Everyday memory performance across the life span: effects of age and noncognitive individual differences.

Gerontologists have long been concerned with the impact of individual-difference factors on memory. This study used a large sample (N = 2,495) of adult volunteers aged 18 to 90 years to determine if a set of individual-difference variables--vocabulary, education, depression, gender, marital status, and employment status--mediates the effects of aging on a wide range of laboratory-analogue tests of everyday memory. The data indicated that age was consistently the most significant predictor of memory performance, followed by vocabulary and gender. Vocabulary totally mediated age effects on a prose memory measure, and partial mediation of aging effects--primarily by vocabulary and gender--was observed on 5 other memory tests. These data suggest that when health samples of volunteers serve as research subjects, these individual differences can affect some memory test scores, but age remains the best overall predictor of memory performance.     

Sex differences in cognition in healthy elderly individuals

ABSTRACT

Sex differences in patterns of cognitive test performance have been attributed to factors, such as sex hormones or sexual dimorphisms in brain structure, that change with normal aging. The current study examined sex differences in patterns of cognitive test performance in healthy elderly individuals. Cognitive test scores of 957 men and women (age 67–89), matched for overall level of cognitive test performance, age, education, and depression scale score, were compared. Men and women were indistinguishable on tests of auditory divided attention, category fluency, and executive functioning. In contrast, women performed better than men on tests of psychomotor speed and verbal learning and memory, whereas men outperformed women on tests of visuoconstruction and visual perception. Our finding that the pattern of sex differences in cognition observed in young adults is observed in old age has implications for future studies of both healthy elderly individuals and of those with cognitive disorders.     

The sensory‐cognition association in adulthood: Different magnitudes for processing speed,inhibition, episodic memory,and false memory?

One hundred and forty-six participants (age range = 20-80) completed a battery of tests designed to measure visual acuity, processing speed, inhibition, episodic memory and false memory. The relations between visual acuity and general cognitive ability, as well as between visual acuity and the indicators of this construct, were evaluated with structural equation modeling. The measurement model confirmed that the indicators of the individual cognitive abilities could be grouped into a general cognitive functioning factor. However, the relation between episodic and false memory was not completely explained by the shared association with this general factor. Furthermore, visual acuity predicted approximately half of the age-related variance in the general cognition factor. Also, the proportion of age-related variance shared with vision was highest in inhibition and lowest in false memory. The results are discussed in the light of common cause accounts of cognitive aging.     

Cumulative mild head injury (CMHI) among college rugby players: A replication and extension study

We investigated the prevalence of cumulative mild head injury (CMHI) symptoms among college student rugby players pre- and post-season. The players completed a number of neuropsychological tests known to be sensitive to CMHI effects: vocabulary, working memory, motor coordination, and a self-report Post Concussive Symptomology (PCS) checklist. A total of 18 rugby players registered at a South African university were participants (age range 18 to 24 years, SD?=?2.02 years). Data were analysed utilising Fishers Exact Test comparisons of pre- and post-season mean scores. There was significant variability on mean scores between the rugby forwards and backline players in terms of verbal memory and concept formation, cognitive flexibility, working memory, and visual motor-processing speed. Poorer overall scores from the rugby forwards may also be indicative of depression as they reported more insomnia and anger on the PCS than the backline players.     

Loneliness is associated with a greater self-reference effect in episodic memory when compared against a close friend

Loneliness describes a negative experience associated with perceived social disconnection. Despite the clear links between loneliness and mental and physical health, relatively little is known about how loneliness affects cognition. In this study, we tested the effect of loneliness on cognitive distance between the self and others, using a task in which participants completed a surprise memory task for adjectives implicitly encoded in relation to the self, a close friend or a celebrity. We assessed item memory sensitivity, metacognitive sensitivity, metacognitive efficiency and source memory for positive and negative words. In addition, participants reported their trait loneliness and depression. Results revealed an overall self-referential advantage compared with both friend and celebrity encoded items. Likewise, a friend-referential advantage was identified compared to celebrity-encoded items. Individuals who experienced more loneliness showed a greater self-referential bias in comparison to words encoded in relation to a close friend, and a smaller friend-referential bias in comparison to words encoded in relation to celebrity. These findings suggest that loneliness is reflected in a greater cognitive distance between the self and close friends in relation to memory biases. The results have important implications for understanding the social contextual effects on memory and the cognitive ramifications of loneliness.     

认知疲劳效应对内隐记忆与外显记忆的影响

本研究通过比较内隐记忆与外显记忆受到认知疲劳影响的情况,以了解内隐记忆的自动化加工机制。实验采用被试内设计,使用词汇判断与词汇再认任务测量内隐记忆与外显记忆。实验结果发现,相对于控制组,疲劳组的被试在完成疲劳任务后内隐记忆成绩显著下降,而外显记忆没有受到影响。结果说明相对于外显记忆,内隐记忆更容易受到认知疲劳影响。内隐记忆虽然是无意识的认知加工,但是与其他自动化加工具有不同的特征。     

认知疲劳效应对内隐记忆与外显记忆的影响

本研究通过比较内隐记忆与外显记忆受到认知疲劳影响的情况,以了解内隐记忆的自动化加工机制。实验采用被试内设计,使用词汇判断与词汇再认任务测量内隐记忆与外显记忆。实验结果发现,相对于控制组,疲劳组的被试在完成疲劳任务后内隐记忆成绩显著下降,而外显记忆没有受到影响。结果说明相对于外显记忆,内隐记忆更容易受到认知疲劳影响。内隐记忆虽然是无意识的认知加工,但是与其他自动化加工具有不同的特征。     

The long-term effects of mild head injury on short-term memory for visual form, spatial location, and their conjunction in well-functioning university students

Research has suggested the presence of subtle long-term cognitive changes in otherwise well-functioning individuals who have previously sustained a mild head injury (MHI). This paper investigated the long-term effects of MHI on visual, spatial, and visual-spatial short-term memory in well-functioning university students. Sixteen students who reported having sustained a MHI were compared to 16 controls on tests of short-term memory (STM) for abstract polygons in haphazardly arranged locations. The three tests differed only in the requirements for recall (shapes for the visual task, locations for the spatial task, and the shapes in their respective locations for the visual-spatial task). MHI participants were selectively impaired on spatial memory, suggesting that tasks of spatial STM may be more sensitive, compared to tasks of visual STM, to the subtle long-term cognitive changes that may be present after a MHI.     

The rise and fall of immediate and delayed memory for verbal and visuospatial information from late childhood to late adulthood

Over 100,000 verbal and visuospatial immediate and delayed memory tests were presented via the Internet to over 28,000 participants in the age range of 11 to 80. Structural equation modeling pointed to the verbal versus visuospatial dimension as an important factor in individual differences, but not the immediate versus delayed dimension. We found a linear decrease of 1% to 3% per year in overall memory performance past the age of 25. For visuospatial tests, this decrease started at age 18 and was twice as fast as the decrease of verbal memory. There were strong effects of education, with the highest educated group sometimes scoring one full standard deviation above the lowest educated group. Gender effects were small but as expected: women outperformed men on the verbal memory tasks; men outperformed women on the visuospatial tasks. We also found evidence of increasing proneness to false memory with age. Memory for recent news events did not show a decrease with age.     

The interactive effects of age,education, and BMI on cognitive functioning

We examined the moderating effects of age and cognitive reserve on the relationship between body mass index (BMI) and processing speed, executive function, and working memory based on the literature suggesting that obese individuals perform more poorly on measures of these abilities. Fifty-six healthy, dementia-free community-dwelling older (mean age 65.72 ± 7.40) and younger (mean age 21.10 ± 2.33) adults completed a neuropsychological battery and reported height and weight. Mixed effects models were used to evaluate the interactive effects of age, education (a proxy for cognitive reserve), and BMI on cognitive scores. Higher education was protective for executive deficits in younger, but not older adults. Age differences in executive functions were reduced at higher education levels but increased in individuals with higher BMI. Results suggest the inter-relationships between cognitive reserve – as measured by education – and BMI differ across age, and that obesity may accelerate the cognitive aging process.     

Natural teeth and cognitive function in humans

A number of neurobiological, psychological and social factors may account for cognitive impairment. In animal studies a relation between dental status and cognitive performance has been found. It is unclear whether such a relation exists for humans. In a first step we compared the performance of 1,351 participants (53% women, 47% men; age M = 54.0) with natural teeth to 487 edentulous participants (59% women, 41% men; age M = 71.3) on 12 cognitive tests. The natural teeth group had a lower mean age, fewer women, more years of education, higher mini-mental state (MMSE), and performed significantly higher on several cognitive tests. In a subsequent analysis, the cognitive performance of a subset of the participants (50-85 years) was examined. In this analysis, 211 had natural dentition and 188 were edentulous. The groups were matched for gender, age, social variables, diseases, stress and MMSE. The cognitive disadvantage of the edentulous group was still apparent. The results suggest that functional natural teeth relate to relatively preserved cognitive functioning in older age.