妊娠期肝内胆汁淤积症胎儿不良预后原因探索

妊娠期肝内胆汁淤积时,在各种机制作用下,往往在妊娠晚期发生胎儿猝死等不良预后,但机制尚不清楚,还在不断的探索之中.主要从胎盘结构因素、胆汁酸的作用、血管及血管调节因素三个方面分析妊娠期肝内胆汁淤积症不良预后的原因,旨在研究妊娠期肝内胆汁淤积症患者胎儿不良预后的原因中所体现的哲学观点.     

探索产科领域的百慕大之谜

妊娠肝内胆汁淤积症(ICP)往往在妊娠晚期发生胎儿猝死,但机制尚不清楚.孕妇和胎儿体内高浓度胆汁酸水平是ICP的显著临床特点.胆汁酸对实验动物心肌细胞具有毒性作用.深入研究胆汁酸对胎儿心脏的毒性作用,有可能揭示胎儿死亡之谜.     

妊娠期肝内胆汁淤积症研究中的认识论

妊娠期肝内胆汁淤积症是一种常见的妊娠晚期并发症,临床上以皮肤瘙痒和黄疸为特征,伴有胆汁酸、肝酶等生化指标的异常。其对母体影响较小,但可以引起早产、胎窘和不明原因的死胎,对围生儿的严重危害使其受到了产科医生的重视。因此,有必要通过回顾妊娠期肝内胆汁淤积症的认识过程来看医学认识发展中所体现的哲学观点。     

妊娠期肝内胆汁淤积症研究中的认识论

妊娠期肝内胆汁淤积症是一种常见的妊娠晚期并发症,临床上以皮肤瘙痒和黄疸为特征,伴有胆汁酸、肝酶等生化指标的异常。其对母体影响较小,但可以引起早产、胎窘和不明原因的死胎,对围生儿的严重危害使其受到了产科医生的重视。因此,有必要通过回顾妊娠期肝内胆汁淤积症的认识过程来看医学认识发展中所体现的哲学观点。     

MDR3基因在妊娠期肝内胆汁淤积症中的研究及思考

妊娠期肝内胆汁淤积症(intrahepatic cholestasis of pregnancy,ICP)病因复杂,目前研究认为遗传因素在其发病机制中起着相当关键的作用。其中MDR3基因与ICP的发病尤为密切。文章从哲学的角度对MDR3基因的发现过程以及未来的发展前景展开了综合分析。     

多角度认识妊娠期肝内胆汁淤积症

妊娠期肝内胆汁淤积症是妊娠晚期特发性疾病,以皮肤瘙痒、胆汁酸增高及肝功能损害为特征.对孕产妇危害较小,对围产儿产生严重后果,使围产儿患病率、死亡率增加.其发病机制尚不明确,许多研究表明它是一种多因素疾病.任何事物都是辨证统一的,在临床中运用辨证的眼光看待疾病,可以促进对疾病的认识.     

妊娠期肝内胆汁淤积症研究中的因果论

妊娠期肝内胆汁淤积症是一种常见的妊娠晚期并发症,对围产儿的危害极大,其确切的病因及发病机制尚未十分清楚。只有了解了疾病的起因,才能更好地进行防治。凡病必有其因,以果推因,再取因治果,这是典型的因果论的应用。     

妊娠期肝内胆汁淤积症研究中的因果论

妊娠期肝内胆汁淤积症是一种常见的妊娠晚期并发症,对围产儿的危害极大,其确切的病因及发病机制尚未十分清楚.只有了解了疾病的起因,才能更好地进行防治.凡病必有其因,以果推因,再取因治果,这是典型的因果论的应用.     

妊娠期高血压疾病的系统论思考

妊娠期高血压疾病是妊娠期常见而又严重危害母儿健康的疾病。从胎盘浅着床,血管内皮受损,遗传因素,免疫机制探讨了妊娠期高血压疾病的发病机制。随着研究的深入,免疫机制在妊娠期高血压疾病的发病中的作用越来越受到重视。介绍了APS最新的治疗进展,为今后的APS发病机制研究及临床治疗带来更多的启示。     

妊娠期高血压疾病的系统论思考

妊娠期高血压疾病是妊娠期常见而又严重危害母儿健康的疾病.从胎盘浅着床,血管内皮受损,遗传因素,免疫机制探讨了妊娠期高血压疾病的发病机制.随着研究的深入,免疫机制在妊娠期高血压疾病的发病中的作用越来越受到重视.介绍了APS最新的治疗进展,为今后的APS发病机制研究及临床治疗带来更多的启示.     

动态颅内压监测技术的进展

动态颅内压（ICP）监测是重危颅脑疾病病人脑功能的监测技术之一,对颅高压病人的临床诊断、指导治疗和判断预后都有着重要的意义。多种颅内压监测方法被使用于临床。本文综述近年来颅内压监测方法的进展,着重介绍创伤性和非创伤性颅内压监测法,比较其优缺点,评价其临床价值及发展方向。     

The Epicurean View of Death

The Epicurean view is that there is nothing bad about death, and we are wrong to loathe it. This paper distinguishes several different such views, and shows that while some of them really would undermine our loathing of death, others would not. It then argues that any version that did so could be at best vacuously true: If there is nothing bad about death, that can only be because there is nothing bad about anything.     

对2010AHACPR-ECC指南及相关问题的思考

心肺复苏是院前急救人员的必备技能,是挽救猝死等危急重症患者生命的首要方法。2010美国心脏协会心肺复苏及心血管急救（AHA CPR-ECC）指南发表至今3年有余,广大院前急救人员仍然存在诸多问题和困惑,猝死的复苏成功率也无明显提高,针对这些问题和困惑,笔者提出了相应的看法和建议,包括（1）该不该删去“听、看、感”;（2）判断循环是否应该结合具体情况;（3）施救者位置与体位是否应该标准化;（4）打开气道时施救者手型与位置是否应该标准化;（5）心脏按压频率如何把握;（6）是否应该掐压人中穴;（7）如何提高复苏成功率;（8）心脏按压板的应用问题;（9）医学院校教科书应当与时俱进。研究并解决好以上问题,对我国院前急救实践或有裨益。     

脑梗死急性期应重视高血糖的处理

脑梗死急性期往往可以检测到血糖升高,而高血糖与脑梗死的转归不良有关。脑梗死急性期高血糖的机制不仅为应激性血糖增高,还可能是多种因素共同作用的结果。注射胰岛素治疗不仅可降低血糖,而且通过对脑组织的直接保护作用减轻脑组织损伤。     

The Lucretian Puzzle and the Nature of Time

If a person’s death is bad for him for the reason that he would have otherwise been intrinsically better off, as the Deprivation Approach says, does it not follow that his prenatal nonexistence is bad for him as well? Recently, it has been suggested that the “A-theory” of time can be used to support a negative answer to this question. In this paper, I raise some problems for this approach.     

LESS GOOD BUT NOT BAD: IN DEFENSE OF EPICUREANISM ABOUT DEATH

In this article I defend innocuousism– a weak form of Epicureanism about the putative badness of death. I argue that if we assume both mental statism about wellbeing and that death is an experiential blank, it follows that death is not bad for the one who dies. I defend innocuousism against the deprivation account of the badness of death. I argue that something is extrinsically bad if and only if it leads to states that are intrinsically bad. On my view, sometimes dying may be less good than living, but it is never bad to die.     

Death, Badness, and the Impossibility of Experience

Some have argued (following Epicurus) that death cannot be a bad thing for an individual who dies. They contend that nothing can be a bad for an individual unless the individual is able to experience it as bad. I argue against this Epicurean view, offering examples of things that an individual cannot experience as bad but are nevertheless bad for the individual. Further, I argue that death is relevantly similar.     

Biobehavioral factors in sudden cardiac death

The authors examine the recent literature on psychological factors and sudden cardiac death and explore the mediating psychophysiological processes by which these variables may be associated. Direct evidence that psychosocial stressors and their correlates may be causally linked with sudden cardiac death in humans is not conclusive, but there is abundant convergent evidence that several physiological precursors of sudden death may be promoted by psychological challenge, especially in persons with coronary heart disease. The authors call for increased attention to the acute effects of psychological events on cardiovascular health.